Intalith CR Tablet (Lithium Carbonate)

Lithium Carbonate ER Tablets Description

Lithium carbonate extended-release tablets USP contain lithium carbonate USP, a white odorless alkaline powder with molecular formula Li2CO3 and molecular weight 73.89. Lithium is an element of the alkali metal group with atomic number 3, an atomic weight of 6.94, and an emission line at 671 nm on the flame photometer. It is also sold under the brand name Eskalith. Each light pink to pink colored circular, biconvex, film-coated, extended-release tablet contains 300 mg of lithium carbonate USP. This slowly dissolving film-coated tablet is designed to give lower serum lithium peak concentrations than those obtained with conventional oral lithium dosage forms. Inactive ingredients consist of sodium chloride, povidone, sorbitol, sodium starch glycolate, sodium lauryl sulfate, calcium stearate VG, hypromellose, titanium dioxide, polyethylene glycol, and iron oxide red.; Lithium Carbonate ER is a mental health medication thathelps in Mania and bipolar disorder.

Uses of Eskalith Tablet

Lithium is used to treat and prevent mania (exaggerated emotions and over-excitability), hypomania (a milder form of mania), bipolar diseases (mood changes with alternating periods of elation and depression), aggressive and self-harming behavior when other drugs are not effective. It is sometimes used for the treatment of low white blood count due to cancer treatment and improving urine output in patients suffering from excess antidiuretic hormone (ADH) disease.

How it works

Lithium is a mood-stabilizing drug. It works by interfering with the production and uptake of chemicals called neurotransmitters in the nerves, thereby restoring the balance in the brain.

Common side effects of Intalith CR Tablet (Lithium Carbonate)

Decreased memory, Impotence, Decreased libido, Increased frequency of urination, Increased skin and tongue pigmentation, Confusion, Increased thirst, Diarrhea, Fine hand tremors, Muscle weakness, Dry mouth, Mild nausea or vomiting, Headache, Weight gain, Altered taste perception, Kidney abnormalities

Lithium Carbonate ER Tablets - Clinical Pharmacology

Preclinical studies have shown that lithium alters sodium transport in nerve and muscle cells and affects a shift toward intraneuronal metabolism of catecholamines, but the specific biochemical mechanism of lithium action in mania is unknown.

Indications and Usage for Lithium Carbonate ER Tablets

Lithium carbonate extended-release tablets USP are indicated in the treatment of manic episodes of Bipolar Disorder. Bipolar Disorder, Manic (DSM-IV) is equivalent to Manic Depressive illness, Manic, in the older DSM-II terminology. Lithium carbonate extended-release tablets USP are also indicated as a maintenance treatment for individuals with a diagnosis of Bipolar Disorder. Maintenance therapy reduces the frequency of manic episodes and diminishes the intensity of those episodes which may occur.

Typical symptoms of mania include pressure of speech, motor hyperactivity, reduced need for sleep, flight of ideas, grandiosity, elation, poor judgment, aggressiveness, and possibly hostility. When given to a patient experiencing a manic episode, lithium may produce a normalization of symptomatology within 1 to 3 weeks.

Precautions of Intalith CR Tablet (Lithium Carbonate)

• Take Eskalith Tablet (Lithium Carbonate) exactly as prescribed by your healthcare provider. Do not change the dosage or stop taking it without consulting your doctor.
• Inform your doctor about any other medications, including over-the-counter drugs and herbal supplements, that you are currently taking. Some medications can interact with lithium carbonate, so it's important to discuss potential drug interactions.
• Maintain a consistent level of salt and fluid intake while on lithium therapy. Changes in salt and fluid levels can affect the blood levels of lithium, so it's important to follow your doctor's instructions.
• Regularly monitor your blood levels of lithium as directed by your doctor. This helps ensure that you are receiving the correct dosage and that it remains within the therapeutic range.
• Inform your doctor if you experience any new or worsening symptoms, such as increased thirst, excessive urination, persistent nausea, diarrhea, tremors, or changes in mood. These could be signs of lithium toxicity and may require an adjustment of your dosage.

Drug Interactions with Intalith CR Tablet (Lithium Carbonate)

• Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and naproxen can increase the risk of lithium toxicity. Avoid taking these medications without consulting your doctor.
• Diuretics (water pills) like hydrochlorothiazide may reduce the effectiveness of lithium and lead to increased lithium levels in the blood. Your doctor may need to adjust your dosage or closely monitor your lithium levels if you need to take diuretics.
• Antidepressants, antipsychotics, and other psychiatric medications may interact with lithium carbonate. Your doctor should carefully monitor your response if you are taking any of these medications concurrently.

FAQs:

Intalith CR Tablet (Lithium Carbonate)

Is Intalith CR Tablet the only medication used for bipolar disorder treatment?

No, bipolar disorder is usually treated with a combination of medications, including mood stabilizers like lithium carbonate, antipsychotics, and antidepressants. The specific treatment plan is tailored to each individual's symptoms and needs.

How long does it take for Intalith CR Tablet to start working?

The onset of action of Intalith CR Tablet varies from person to person. It may take several weeks to notice significant improvements in mood stabilization. It's important to continue taking the medication as prescribed, even if the effects are not immediately apparent.

Can I drink alcohol while taking Intalith CR Tablet?

It is generally recommended to avoid alcohol while taking Intalith CR tablets. Alcohol can increase the side effects of lithium, such as drowsiness, dizziness, and impaired coordination. It can also interfere with the effectiveness of the medication.

Are there any specific dietary restrictions while taking Intalith CR Tablet?

While there are no specific dietary restrictions, maintaining a consistent level of salt and fluid intake is important to keep lithium blood levels stable. Changes in salt and fluid intake can affect the blood levels of lithium, so it's advisable to follow your doctor's instructions regarding salt and fluid intake.