Nizoral Anti-Dandruff Shampoo with 2% Ketoconazole-50ml(Nizral Shampoo) | Used to Control Flaking, Scaling, and Itching Caused by Dandruff
Nizral Shampoo, contains 2% Ketoconazole, a medicated shampoo for the effective treatment and prevention of dandruff, seborrhoeic dermatitis, and fungal scalp infections. It belongs to the class of antifungal drugs known as azole antifungals. Nizoral is a brand name for ketoconazole-based products.
Product Overview
Nizoral Anti-Dandruff Shampoo (Nizral Shampoo) is a clinically proven, medicated treatment designed to address the root cause of dandruff rather than just managing the symptoms. It contains Ketoconazole, a powerful antifungal agent that specifically targets Malassezia, a fungus-like organism that naturally lives on the scalp but can cause irritation, flaking, and itching when it overgrows. Unlike regular shampoos, Nizoral 2% is formulated to bind to the natural proteins of the hair and scalp, allowing it to continue working even after rinsing. This 50ml variant is ideal for targeted treatment cycles, providing a potent solution for stubborn dandruff, seborrheic dermatitis, and the associated scalp scales.
Product Composition
- Active Ingredient: Ketoconazole (2% w/v)
- Base: Foaming shampoo base with conditioning agents.
- Excipients: Sodium laureth sulfate, disodium laureth sulfosuccinate, PEG-120 methyl glucose dioleate, and hydrolyzed collagen.
- Formulation: Clear, pinkish-orange viscous liquid.
- Action Category: Imidazole Antifungal / Therapeutic Shampoo.
Product Specifications
| Feature | Description |
| Therapeutic Class | Antifungal |
| Route of Administration | Topical (Scalp) |
| Indication | Dandruff and Seborrheic Dermatitis |
| Frequency of Use | Twice weekly for treatment |
| Fragrance | Fresh, clean scent |
Mechanism of Action
- Fungal Wall Interference: Ketoconazole inhibits the synthesis of ergosterol, a vital component of the fungal cell membrane.
- Enzyme Blockage: It disrupts the enzyme cytochrome P450, which leads to the accumulation of toxic methylated sterols within the fungus.
- Malassezia Eradication: By compromising the structural integrity of the Malassezia yeast, the shampoo stops the excessive shedding of skin cells (flaking).
- Anti-inflammatory Effect: By reducing the yeast population, it indirectly decreases the secondary inflammation and redness that often accompany dandruff and seborrheic dermatitis.
Key Benefits
- Treats the Source: Goes beyond temporary surface cleaning by killing the fungi responsible for dandruff.
- Long-Lasting Relief: The active ingredient remains effective on the scalp for several days after application.
- Scalp Health Improvement: Effectively reduces stubborn itching and redness, restoring a comfortable scalp environment.
- Hair Compatibility: Formulated to be used on all hair types, including color-treated, chemically processed, or gray hair.
- Prevents Recurrence: Regular use during the maintenance phase helps keep the scalp fungus-free and prevents the return of flakes.
Usage
Usage Guidelines
| Step | Instruction |
| Wetting | Thoroughly wet the hair and scalp with lukewarm water before application. |
| Application | Apply a small amount of shampoo to the scalp and massage gently to produce a rich lather. |
| Absorption | Leave the lather on the scalp for 3 to 5 minutes to allow the medication to penetrate. |
| Rinsing | Rinse the hair and scalp thoroughly with plenty of water. |
| Second Wash | A second application is generally not required unless specifically advised. |
Dosage & Administration
Nizral Shampoo should be used according to a structured schedule for the best results:
Treatment Phase: Use twice a week for 2 to 4 weeks to clear the infection and eliminate existing dandruff.
Maintenance Phase: Once the scalp is clear, use once every 1 or 2 weeks to prevent the dandruff from returning.
Pityriasis Versicolor: If used for body patches, apply to the affected areas once daily for a maximum of 5 days.
Conditioning: You may use your regular shampoo and conditioner in between Nizral treatments if desired.
Safety Precautions: Avoid contact with the eyes. If the shampoo gets into the eyes, rinse immediately with cold water.
Hair Color: While safe for most hair, it may occasionally cause a slight change in the texture or color of chemically damaged or gray hair.
Persistence: If the condition of the scalp does not improve after 4 weeks of treatment, consult a professional for further evaluation.
Uses
Dandruff Control: Effectively eliminates stubborn flaking and scales by targeting the underlying fungal cause.
Seborrheic Dermatitis: Treats the inflammatory condition of the scalp characterized by red, itchy, and greasy skin patches.
Pityriasis Capitis: Provides relief from the persistent itching and irritation associated with various types of scalp scaling.
Pityriasis Versicolor: When used as a body wash, it helps treat and manage fungal patches that cause skin discoloration on the trunk and shoulders.
Scalp Health Maintenance: Prevents the recurrence of fungal overgrowth when used as part of a regular maintenance routine.
Side effects
Common Side Effects
- Mild scalp dryness
- Itching or slight irritation
- Temporary increase in hair shedding
- Greasy or dry hair texture changes
Less Common Side Effects
- Scalp redness or burning sensation
- Hair discoloration or texture changes
- Oily or flaky scalp during initial use
- Mild hair thinning (temporary in some cases)
Rare Side Effects
| Rare Side Effect | Description |
|---|---|
| Severe Scalp Irritation | Intense redness, burning, or discomfort requiring discontinuation |
| Allergic Reaction | Rash, swelling, or severe itching on scalp or skin |
| Contact Dermatitis | Inflammation due to sensitivity to ketoconazole or ingredients |
| Hair Texture Changes | Persistent dryness or brittleness of hair |
| Worsening Hair Fall | Rare temporary increase in hair fall during early treatment phase |
Safety Note
- Discontinue use if severe irritation or allergic reaction occurs
- Consult a doctor if symptoms persist or worsen
- Use only as directed for effective dandruff and fungal scalp treatment
FAQs
Q: What is Nizoral Anti-Dandruff Shampoo used for?
A: Nizoral Anti-Dandruff Shampoo is used for the treatment and prevention of dandruff, seborrhoeic dermatitis, and fungal scalp infections. It contains 2% Ketoconazole, a powerful antifungal agent that eliminates Malassezia yeast responsible for dandruff and scalp irritation, providing fast and lasting relief from flaking, itching, and scalp discomfort.
Q: How does Nizoral Anti-Dandruff Shampoo work?
A: Nizoral Anti-Dandruff Shampoo works by inhibiting the synthesis of Ergosterol, an essential component of the fungal cell membrane of Malassezia yeast. Without Ergosterol, the fungal cell membrane becomes unstable and permeable, leading to the death of the yeast and elimination of the root cause of dandruff, scalp flaking, and seborrhoeic dermatitis.
Q: How should I use Nizoral Anti-Dandruff Shampoo?
A: Wet the hair and scalp thoroughly before application. Apply a sufficient amount of Nizoral Anti-Dandruff Shampoo to the scalp and hair, lather well, and leave it on for 3 to 5 minutes to allow the active ingredient to work effectively. Rinse thoroughly with water. Use twice weekly for 2 to 4 weeks for treatment and once every one to two weeks for maintenance and prevention as directed by your dermatologist or trichologist.
Q: How long does it take for Nizoral Anti-Dandruff Shampoo to show results?
A: Most users begin to notice a visible reduction in dandruff, scalp flaking, and itching within the first two to four weeks of regular use. For seborrhoeic dermatitis, optimal results are typically achieved after completing the full recommended treatment course. Consistent use for maintenance helps prevent recurrence of dandruff and scalp fungal conditions.
Q: Can Nizoral Anti-Dandruff Shampoo be used for seborrhoeic dermatitis?
A: Yes, Nizoral Anti-Dandruff Shampoo with 2% Ketoconazole is one of the most widely recommended medicated shampoos for seborrhoeic dermatitis of the scalp. It effectively eliminates the Malassezia yeast responsible for seborrhoeic dermatitis and reduces associated scalp inflammation, redness, flaking, and itching with regular use under dermatologist supervision.
Q: Can Nizoral Anti-Dandruff Shampoo be used on the face and body?
A: Yes, Nizoral Anti-Dandruff Shampoo can be used on the face and body for the treatment of seborrhoeic dermatitis and fungal skin conditions affecting these areas. Apply it as a body wash or facial cleanser, leave on for a few minutes, and rinse thoroughly. Consult your dermatologist for guidance on use outside the scalp area.
Q: How often should I use Nizoral Anti-Dandruff Shampoo?
A: For active treatment of dandruff and seborrhoeic dermatitis, use Nizoral Anti-Dandruff Shampoo twice weekly for 2 to 4 weeks. For ongoing maintenance and prevention of recurrence, use once every one to two weeks or as directed by your dermatologist. Avoid using it more frequently than recommended to prevent scalp dryness or irritation.
Q: Can I use my regular shampoo alongside Nizoral Anti-Dandruff Shampoo?
A: Yes, you can use your regular shampoo on days when you are not using Nizoral Anti-Dandruff Shampoo. However, ensure that your regular shampoo does not contain harsh chemicals or sulfates that may irritate the scalp during treatment. Consult your dermatologist for a complete hair care routine that complements your dandruff treatment.
Q: Can Nizoral Anti-Dandruff Shampoo cause hair loss?
A: Nizoral Anti-Dandruff Shampoo is not known to cause hair loss when used as directed. In fact, by treating scalp conditions such as seborrhoeic dermatitis and fungal infections that can contribute to hair thinning, it may help support a healthier scalp environment for improved hair growth. Consult your dermatologist if you notice unusual hair loss during treatment.
Q: Is Nizoral Anti-Dandruff Shampoo safe for coloured or chemically treated hair?
A: Individuals with coloured, permed, or chemically treated hair should consult their dermatologist or trichologist before using Nizoral Anti-Dandruff Shampoo. Medicated shampoos may affect the longevity of hair colour or chemical treatments in some individuals. Always perform a strand test before full application if you have chemically treated hair.
Q: Can Nizoral Anti-Dandruff Shampoo be used for tinea versicolor?
A: Yes, Nizoral Anti-Dandruff Shampoo with 2% Ketoconazole is effective for treating tinea versicolor, a common fungal skin infection that causes discoloured patches on the skin. Apply it to the affected skin areas, leave on for a few minutes, and rinse thoroughly as directed by your dermatologist for effective antifungal treatment of tinea versicolor.
Q: Is Nizoral Anti-Dandruff Shampoo safe for children?
A: Nizoral Anti-Dandruff Shampoo should be used in children only under the supervision and guidance of a paediatrician or dermatologist. Always consult a healthcare professional before using any medicated shampoo on children to ensure safe and appropriate use based on the child's age and scalp condition.
Q: Is Nizoral Anti-Dandruff Shampoo safe during pregnancy and breastfeeding?
A: Pregnant and breastfeeding women should consult their doctor before using Nizoral Anti-Dandruff Shampoo. While topical Ketoconazole has minimal systemic absorption, medical guidance is always recommended before starting any medicated shampoo treatment during pregnancy or lactation to ensure the safety of both mother and baby.
Q: Can dandruff recur after using Nizoral Anti-Dandruff Shampoo?
A: Dandruff and seborrhoeic dermatitis can recur after treatment as Malassezia yeast is a natural part of the scalp flora. To prevent recurrence, use Nizoral Anti-Dandruff Shampoo for maintenance once every one to two weeks after completing the treatment course.
Interactions
Hair and Scalp Product Interactions
- Avoid using with other medicated anti-dandruff shampoos unless advised by a doctor
- Do not combine with strong scalp treatments (like coal tar, salicylic acid, or selenium sulfide) without guidance, as it may increase irritation or dryness
- Limit use of hair oils or heavy styling products immediately before or after application
Medication and Treatment Interactions
| Product / Treatment | Interaction Effect |
|---|---|
| Other Antifungal Shampoos | May increase scalp dryness or irritation without added benefit |
| Topical Steroid Scalp Products | Can mask symptoms and delay proper treatment response |
| Chemical Hair Treatments (Dyes, Perms) | May increase scalp sensitivity and irritation |
| Strong Exfoliating Scalp Products | Can worsen dryness and flaking when used together |
Lifestyle and Usage Interactions
- Avoid excessive heat styling (blow dryers, straighteners) immediately after use
- Maintain a gentle hair care routine to prevent scalp irritation
- Do not share combs, towels, or hair accessories to prevent fungal spread
Important Notes
- Inform your doctor about all scalp and hair treatments you are using
- Use consistently as directed for best antifungal results
- Discontinue use and consult a healthcare professional if severe irritation or worsening scalp condition occurs
- Rinse thoroughly after use to avoid residue buildup and irritation
| Manufacturer | : | Intas Pharma, India |
| Trade Name | : | Nizoral |
| Generic Search | : | Ketoconazole |
| Strength | : | 2% (50 ml) |
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