DIZONE Tablet (Disulfiram) Used to Treat Alcoholism

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Dizone Tablet contains Disulfiram is used to support the treatment of chronic alcohol dependence. It works by causing unpleasant reactions if alcohol is consumed, helping discourage drinking and promote long-term abstinence. Dizone is most effective when combined with counseling, behavioral therapy, and a comprehensive de-addiction program. Take it only under the supervision of a healthcare professional and avoid alcohol in all forms during treatment.

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Dizone 250mg Tablet (Disulfiram 250mg)
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30 Tablet/s $4.30
60 Tablet/s $7.80
90 Tablet/s $11.10

Product Overview

Dizone Tablet (Disulfiram) is a medication used to treat chronic or deep-rooted alcoholism. It is an effective aid in discouraging drinking by causing unpleasant side effects when alcohol is consumed while taking the medication. DIZONE Tablet contains Disulfiram, an alcohol-deterrent medicine that helps people maintain abstinence from alcohol. It works by inhibiting the enzyme aldehyde dehydrogenase, which causes a buildup of acetaldehyde when alcohol is consumed. This produces unpleasant reactions that discourage alcohol intake.

Disulfiram does not directly remove alcohol cravings but acts as a support tool by creating a strong physical reaction when alcohol is consumed.

Product Composition

  • Disulfiram – Active ingredient
  • Alcohol deterrent medicine
  • Aldehyde dehydrogenase inhibitor

Product Specification

ParameterDetails
Active IngredientDisulfiram
Medicine ClassAlcohol Deterrent
Dosage FormTablet
Main ActionPrevents alcohol breakdown
Therapeutic UseSupport in alcohol dependence management

 

Key Benefits

  • Supports Alcohol Avoidance:
    Helps discourage alcohol consumption by causing unpleasant reactions when alcohol is taken.
  • Helps Maintain Abstinence:
    Provides support for individuals working toward staying away from alcohol.
  • Reduces Alcohol Reward Effect:
    Changes the body’s response to alcohol, making drinking less appealing.
  • Supports Recovery Goals:
    Can be part of a structured approach for managing alcohol dependence.
  • Long-Lasting Action:
    Its effects may continue even after stopping the medicine due to its prolonged enzyme-blocking activity. 

Precaution

Condition / SituationPrecaution
Liver problemsUse cautiously in people with liver disease or abnormal liver function
Heart conditionsInform about heart disease, irregular heartbeat, or circulation problems
Alcohol exposureAvoid alcohol-containing drinks, medicines, and products during treatment
Mental health conditionsInform about severe mood changes or psychiatric conditions
Pregnancy and breastfeedingDiscuss use before taking during pregnancy or breastfeeding

 

Important Precaution Points

  • Alcohol exposure:
    Disulfiram can react with even small amounts of alcohol found in some drinks, medicines, mouthwashes, and food products. Avoiding hidden alcohol sources is important to prevent unwanted reactions.
  • Liver health:
    Disulfiram can affect liver function in some people. Inform about any history of liver problems and watch for symptoms such as unusual tiredness, dark urine, or yellowing of skin or eyes.
  • Heart conditions:
    Alcohol-disulfiram reactions can affect blood pressure and heart function, so people with heart-related conditions should discuss suitability before use.
  • Mental health:
    Inform about significant mood changes, anxiety, or unusual thoughts while using Disulfiram.
  • Pregnancy and breastfeeding:
    Use during pregnancy or breastfeeding should be discussed based on individual health needs.

Usages

▸ Alcohol Deterrent Therapy

DIZONE works by interfering with alcohol metabolism. When alcohol is consumed, increased acetaldehyde levels can cause unpleasant symptoms such as flushing, nausea, and discomfort.

▸ Helps Maintain Drinking Avoidance

The medicine provides a physical deterrent that supports commitment to avoiding alcohol.

▸ Requires Alcohol Avoidance

Alcohol should be avoided from beverages, medicines, foods, and products that may contain alcohol, as reactions can occur.

▸ Long-Acting Effect

Disulfiram’s effect may continue for some time after the last dose because of its prolonged action on alcohol metabolism.

Uses

▸ Alcohol Dependence

DIZONE Tablet is used as a supportive treatment for people who want to stop alcohol consumption. It helps prevent alcohol intake by causing unpleasant physical reactions if alcohol is consumed.

▸ Alcohol Relapse Prevention

Disulfiram may help reduce the chances of returning to alcohol use by creating a deterrent effect against drinking.

▸ Support During Alcohol Recovery

It is used as part of an overall recovery plan to help maintain alcohol-free periods.

 

Side Effects 

Common Side Effects

  • Drowsiness:
    Some people may feel sleepy or less alert while using Disulfiram.
  • Metallic or Garlic-Like Taste:
    A change in taste sensation may occur during treatment.
  • Headache:
    Mild headache may occur in some users.
  • Tiredness:
    Feeling of fatigue or reduced energy may occur.
  • Stomach Discomfort:
    Nausea, vomiting, or digestive discomfort may occur.

Less Common Side Effects

  • Skin rash or itching
  • Dizziness
  • Reduced appetite
  • Mood changes
  • Numbness or tingling sensations

Serious Side Effects

ConditionDetail
Liver problemsYellowing of skin/eyes, dark urine, severe tiredness, or abdominal pain may indicate liver-related issues
Severe allergic reactionSwelling, breathing difficulty, or severe skin reactions may occur rarely
Nerve problemsPersistent numbness, weakness, or tingling may require attention

 

Important Side Effects

  • Mild tiredness, headache, or taste changes may occur during treatment.
  • Digestive discomfort or drowsiness may occur in some individuals.
  • Avoiding alcohol-containing products helps prevent unpleasant Disulfiram reactions.
  • Liver-related symptoms or unusual nerve changes should be evaluated.
  • Individual response to Disulfiram may vary.

FAQs

Q. What is DIZONE Tablet used for?
DIZONE Tablet contains Disulfiram and is used as a supportive treatment for alcohol dependence by helping prevent alcohol consumption.

Q. How does DIZONE Tablet work?
Disulfiram blocks the breakdown of alcohol in the body, causing unpleasant effects when alcohol is consumed.

Q. Does DIZONE reduce alcohol cravings?
Disulfiram mainly works as an alcohol deterrent and does not directly remove cravings.

Q. Can alcohol be consumed while taking DIZONE?
No. Alcohol consumption can cause unpleasant reactions because of the interaction between alcohol and Disulfiram.

Q. How long does the effect of Disulfiram last?
The effect may continue for some time after stopping the medicine due to its long-lasting action in the body.

Q. Can DIZONE be taken with alcohol-containing products?
Products containing alcohol, including some medicines, mouthwashes, or food items, may trigger a reaction and should be avoided.

Q. What type of reaction can occur with alcohol?
Alcohol with Disulfiram may cause flushing, nausea, vomiting, headache, dizziness, and changes in blood pressure.

Q. Can DIZONE be used in liver problems?
People with liver-related conditions should discuss suitability before using Disulfiram.

Q. Can DIZONE cause sleepiness?
Yes, drowsiness or tiredness may occur in some users.

Q. How long does DIZONE take to work?
The effect depends on individual response and consistent use along with avoiding alcohol.

Q. Can DIZONE be stopped suddenly?
Any change in treatment should be discussed, as Disulfiram’s effects may continue after stopping.

 

Interaction

Medicine / SubstancePossible Effect
Alcohol-containing productsMay cause a severe disulfiram-alcohol reaction
MetronidazoleMay increase risk of mental or neurological effects
WarfarinMay increase blood-thinning effects
PhenytoinMay increase phenytoin levels in the body
Certain liver-metabolized medicinesMay affect medicine breakdown

 

Important Interaction Points

  • Alcohol-containing products:
    Combining Disulfiram with alcohol can cause reactions such as flushing, nausea, headache, vomiting, and changes in blood pressure.
  • Metronidazole:
    This combination may increase the risk of neurological side effects and should be discussed before use.
  • Warfarin:
    Disulfiram may enhance the effect of warfarin, which can increase bleeding risk.
  • Phenytoin:
    Disulfiram may increase phenytoin levels, which may require monitoring.
  • Other medicines:
    Inform about all medicines and supplements being used, especially those processed through the liver.
 
 
More Information
Manufacturer:A. Menarini India Pvt Ltdine HCL)
Trade Name:Antabuse
Generic Search:Disulfiram
Strength:250 mg
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