Dizone Tablet (Disulfiram)

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Buy Disulfiram (Dizone 250mg), Disulfiram is used to discourage drinking in patients with chronic alcoholism. This medicine can help in staying away from drinking by causing unpleasantness. Antabuse is another brand name for Disulfiram.

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Dizone 250mg Tablet (Disulfiram 250mg)

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30 Tablet/s $4.30
60 Tablet/s $7.80
90 Tablet/s $11.10

What is Dizone Tablet (Disulfiram)?

Dizone Tablet (Disulfiram) is a medication used to treat chronic or deep-rooted alcoholism. It is an effective aid in discouraging drinking by causing unpleasant side effects when alcohol is consumed while taking the medication. Some common trade names for Disulfiram include Dizone and Antabuse. The way Disulfiram works is by interfering with alcohol metabolism in the body. When alcohol is ingested, it is broken down into a chemical called aldehyde through a natural process. Aldehyde is further broken down by the enzyme aldehyde dehydrogenase, allowing alcohol to be eliminated from the body. However, Disulfiram blocks the action of aldehyde dehydrogenase, leading to increased levels of aldehyde in the blood. As a result, if a person on Disulfiram consumes alcohol, they experience a range of undesirable reactions collectively known as the "aldehyde syndrome." These reactions include flushing of the face, throbbing headache, nausea, vomiting, chest pain, weakness, blurred vision, mental confusion, sweating, choking, breathing difficulties, anxiety, and other discomforting symptoms. These reactions can begin within 10 minutes of alcohol consumption and may persist for an hour or more. It's essential to note that Disulfiram is not a cure for alcoholism but rather serves as a powerful deterrent to drinking. It helps individuals with alcohol addiction to abstain from alcohol by creating negative associations with its consumption.

Uses of Dizone Tablet (Disulfiram)

Disulfiram is a medication primarily employed to treat chronic or deep-rooted alcoholism. Sold under various trade names worldwide, including Antabuse and Dizone, it serves as a deterrent to drinking by inducing unpleasant side effects if alcohol is consumed while taking the drug. These effects can include flushing of the face, headache, nausea, vomiting, chest pain, weakness, blurred vision, mental confusion, sweating, choking, breathing difficulty, and anxiety. The reactions typically begin about 10 minutes after alcohol enters the body and can last for over an hour. Although Disulfiram does not cure alcoholism, it effectively discourages drinking.

How it works

Disulfiram belongs to a group of medicines known as aldehyde dehydrogenase inhibitors. When alcohol is consumed, it undergoes a natural breakdown process, converting it into a chemical called aldehyde, which is further broken down by the enzyme aldehyde dehydrogenase. This allows alcohol to be excreted from the body. Disulfiram interferes with this process, preventing the action of aldehyde dehydrogenase and leading to increased blood levels of aldehydes. As a result, consuming alcohol while on Disulfiram results in a series of unpleasant reactions, known as aldehyde syndrome, including flushing, headaches, sweating, vomiting, visual disturbances, mental confusion, and more. Sensitivity to alcohol is developed, causing these reactions to persist even days after stopping Disulfiram.

Important Information about Dizone Tablet (Disulfiram)

  • Drinking alcohol while on Disulfiram treatment can lead to severe side effects such as nausea, fast heartbeats, flushing, thirst, chest pain, vertigo, or low blood pressure.
  • Avoid taking Disulfiram for at least 12 hours after consuming alcohol, as its effects may still be present even weeks after stopping the medication.
  • Be cautious of common products containing alcohol in small amounts, like cough syrups, mouthwash, tonics, sauces, vinegar, and various food products, as they may also trigger reactions when combined with Disulfiram.
  • Before taking Disulfiram, consult your doctor and discuss any medical conditions you may have, such as liver or kidney disease, thyroid problems, diabetes, brain or mental disorders, epilepsy, or seizure problems. Disulfiram may not be suitable for some individuals or may require dose adjustments and close monitoring.
  • Pregnant or breastfeeding individuals should consult their doctors before taking Disulfiram, as it may pose risks to the unborn baby and could pass into breast milk.

Disulfiram Tablet Manufacturer: Ozone Pharma Ltd

Dosage and Storage

Take Disulfiram strictly as prescribed by your doctor and do not alter the dosage without their advice. Store the medication in a cool, dry place, away from heat and moisture, and keep it out of reach of children and pets.

Missed Dose and Overdose

If you miss a dose, take it as soon as you remember, but avoid taking it if the next dose is imminent. Taking multiple doses too closely together can be dangerous. In case of an overdose, seek immediate medical attention, as it may lead to symptoms such as nausea, vomiting, dizziness, loss of coordination, numbness, tingling, or seizures.

Avoid While Taking Disulfiram/Antabuse

Refrain from consuming alcohol while on Disulfiram treatment, and be cautious of products containing alcohol. Even alcohol fumes from products like paints, thinners, and solvents can trigger reactions.

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Side Effects of Dizone Tablet (Disulfiram)

Disulfiram may cause severe liver problems in some cases. Seek emergency medical attention if you experience allergic reactions such as hives, breathing difficulties, or swelling of the face, lips, tongue, or throat. Other serious side effects include lethargy, dark urine, seizures, yellowing of the skin or eyes, changes in appetite, severe diarrhea, or vomiting. Common and less severe side effects may include skin rash, acne, mild headache, drowsiness, tiredness, impotence, or an unpleasant metallic taste.

Dizone Tablet (Disulfiram) Interaction with Other Drugs

Inform your doctor about any medications, whether prescription, over-the-counter, or herbal, that you are taking before starting Disulfiram treatment. Some medications, including monoamine oxidase inhibitors, isoniazid, tricyclic antidepressants, warfarin, metronidazole, lithium, phenytoin, or theophylline, may interact with Disulfiram and cause adverse effects. Always consult your doctor before starting any new medication.

Expert Advice

  • Avoid alcohol consumption during Disulfiram treatment and for up to 14 days after discontinuation.
  • Disulfiram may cause drowsiness, so refrain from driving or operating machinery if affected.
  • Pregnant or breastfeeding individuals should avoid Disulfiram, and patients with certain medical conditions should discuss its use with their doctors.
  • Patients receiving or recently receiving alcohol or alcohol-containing preparations should not take Disulfiram, as it may lead to severe and potentially life-threatening reactions.
  • Seek immediate medical attention if you experience severe symptoms after stopping Disulfiram, such as flushing, increased body temperature, sweating, nausea, vomiting, itching, anxiety, dizziness, headache, difficulty breathing, rapid heartbeat, chest pain, abnormal heart rhythm, coma, or seizures.

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Dizone Tablet (Disulfiram)

Q: Can I stop taking Dizone (Disulfiram) if I want to drink alcohol occasionally?

A: No, it is not advisable to stop and restart the Dizone treatment. The medication creates a lasting sensitivity to alcohol, even after discontinuation. Consuming alcohol while on or after Dizone use can lead to severe reactions, making it essential to abstain from alcohol completely.

Q: Are there any dietary restrictions while taking Dizone (Disulfiram)?

A: Yes, it's crucial to avoid alcohol-containing products like cough syrups, mouthwash, and certain sauces. Additionally, some herbal supplements and tonics may contain alcohol, leading to adverse reactions when combined with Dizone.

Q: Can Dizone (Disulfiram) be used as a standalone treatment for alcoholism?

A: Dizone is not a standalone cure for alcoholism. It is most effective when used as part of a comprehensive treatment plan that may include counseling, support groups, and behavioral therapies.

Q: Can pregnant or breastfeeding women take Dizone (Disulfiram)?

A: Pregnant and breastfeeding individuals should avoid taking Dizone due to potential risks to the unborn baby and nursing infant. It is essential to consult a healthcare professional for safer alternatives during this period.

Q: How long does Dizone (Disulfiram) stay effective in the body after discontinuation?

A: Dizone's effects can persist for weeks after stopping the medication, as it creates lasting sensitivity to alcohol. Therefore, individuals who have taken Dizone should continue to avoid alcohol consumption to prevent adverse reactions.

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Manufacturer :
Equivalent Brand : Antabuse
Generic Search : Disulfiram
Strength : 250 mg