Zurig Tablets (Febuxostat)
FEBUXOSTAT belongs to a class of anti-gout medications, also known as xanthine oxidase inhibitors, which are widely used to prevent severe gout attacks or flare-ups.Read More
ntroduction of Zurig Tablets (Febuxostat)
FEBUXOSTAT belongs to a class of anti-gout medications, also known as xanthine oxidase inhibitors, which are widely used to prevent severe gout attacks or flare-ups. Gout is a chronic disease caused by the deposition of uric acid crystals in the joints. It is characterized by severe pain and swelling of the affected joints. FEBUXOSTAT prevents sudden attacks of pain caused by severe gout and also reduces pain, swelling and inflammation. FEBUXOSTAT contains febuxostat. It works by inhibiting the enzyme xanthine oxidase (an enzyme that helps your body produce uric acid), thereby reducing the level of uric acid produced in your body. Thus, it reduces the inflammation caused by uric acid crystals in the affected joints, thereby reducing pain, swelling and inflammation. FEBUXOSTAT is used to prevent attacks or flare-ups of gout. FEBUXOSTAT is an oral medication. Swallow the tablet whole with a glass of water. Do not chew, bite or break it. Your doctor will tell you how often you should take FEBUXOSTAT depending on your condition. Common side effects of FEBUXOSTAT nausea, rash, dizziness, diarrhea, pain, rash, incorrect liver function test results, gout flares (sudden onset of severe joint pain, usually in the middle of the night), local swelling due to fluid retention in the tissues (oedema). Most of these FEBUXOSTAT side effects do not require medical attention and gradually go away over time. However, if side effects persist, contact your doctor. Do not stop taking FEBUXOSTAT on your own initiative. Stopping it could make your condition worse and increase your risk of increased uric acid levels and future gout attacks. Tell your doctor if you are allergic to FEBUXOSTAT or any other medicines, if you have heart problems (FEBUXOSTAT can cause heart problems leading to heart attack), kidney/liver disease. Some people have more flare-ups when you start taking FEBUXOSTAT. You should continue to take this medicine even during a gout flare. Your doctor may prescribe a combination treatment to prevent flare-ups when you start FEBUXOSTAT. Safety and efficacy have not been established in children less than 18 years of age, therefore FEBUXOSTAT should not be administered to children. If you are pregnant or breast-feeding, you should inform your doctor before using FEBUXOSTAT.
Uses of Zurig Tablets (Febuxostat)
- Treatment of severe gout, prevention of acute gout attacks.
Directions for Use
Take FEBUXOSTAT with or without food. Do not bite, crush or spoil the tablet. Swallow whole with a glass of water. FEBUXOSTAT should not be taken unless directed by your doctor. Your doctor will tell you how long to take FEBUXOSTAT depending on your medical condition.
Side Effects of Zurig Tablets (Febuxostat)
Like all medicines, FEBUXOSTAT can cause side effects, although not everyone gets them. Common side effects of FEBUXOSTAT include nausea, skin rash, dizziness, and diarrhea, joint pain, rash, incorrect liver function test results, gout flares (severe joint pain) flushing occurs suddenly, often in the middle of the night), local swelling due to fluid retention in the tissues (oedema). These side effects gradually disappear over time. If your condition worsens or becomes unusual, contact your doctor.
Precautions of Zurig Tablets (Febuxostat)
You should avoid taking FEBUXOSTAT if you are allergic to FEBUXOSTAT, if you have heart problems, as it increases your risk of a heart attack. It needs to be used with warning in sufferers with kidney issues and blood issues. Use caution before taking FEBUXOSTAT if you are pregnant or planning to become pregnant, or if you are breast-feeding. Safety and efficacy have not been established in children less than 18 years of age, therefore FEBUXOSTAT should not be administered to children.
Interactions of Zurig Tablets (Febuxostat)
Drug-Drug Interactions: FEBUXOSTAT interacts with anti-cancer immunosuppressants (mercaptopurine, methotrexate) (azathioprine), antidiabetic drugs (rosiglitazone), anti-asthmatic drugs (theophylline).
Food-drug interactions: Drinking alcohol can increase your risk of side effects, so avoid alcohol with FEBUXOSTAT. Limit your diet high in purines.
Drug-disease interactions: Tell your doctor if you have a history of drug allergies, hyperuricemia (unusually high blood uric acid levels), heart disease, liver disease, or kidney disease before taking FEBUXOSTAT.
Does Febuxostat lower uric acid?
Over a 2-hour period, febuxostat reduces serum uric acid levels in a dose-dependent manner. As a result, total daily urinary uric acid excretion decreased with an increase in total daily urinary xanthine excretion.
When should you take febuxostat?
It is first-class to drink it in the morning. If you work shifts or want to take your medicine in the evening, talk to your doctor, nurse or pharmacist. You can take febuxostat with or without meals. Continue taking febuxostat every day to prevent gout attacks.
Is Febuxostat good for the kidneys?
Febuxostat and allopurinol are associated with a higher risk of acute kidney injury (ARI), according to the results of a study published in the Journal of Arthritis Research and Therapy.