Terbiface Forte Tablet ( Terbinafine + Ketoconazole) | Used to Treat Ringworm, Athlete’s Foot and Fungal Infections
Terbiface Forte Tablet (Terbinafine + Ketoconazole) is a broad-spectrum antifungal medicine used for the treatment of stubborn skin, nail, and scalp fungal infections. It works by inhibiting fungal growth and killing infection-causing fungi, helping to relieve symptoms like itching, redness, scaling, and irritation. This medicine is commonly prescribed for ringworm, athlete’s foot, and other dermatophyte infections under medical supervision.
Product Overview
Terbiface Forte Tablet is a powerful dual-action antifungal combination consisting of Terbinafine and Ketoconazole. Terbiface Forte Tablet is specifically formulated to combat a wide spectrum of fungal infections that affect the skin, nails, and scalp. By combining a potent allylamine antifungal with an azole derivative, this treatment effectively inhibits fungal growth through two distinct mechanisms, ensuring a comprehensive approach to eradicating persistent dermatological fungal issues such as tinea corporis, tinea cruris, and refractory scalp infections.
Product Composition
- Terbinafine Hydrochloride 250 mg
- Ketoconazole 100 mg
- Excipients q.s.
Product Specification
| Feature | Details |
| Brand Name | Terbiface Forte Tablet |
| Therapeutic Category | Broad-spectrum Antifungal Agent |
| Form | Oral Tablet |
| Primary Indication | Systemic Fungal and Yeast Infections |
| Storage Requirements | Store in a cool, dry place away from moisture |
Mechanism of Action
- Terbinafine works by inhibiting the enzyme squalene epoxidase, which leads to a deficiency of ergosterol and an accumulation of squalene within the fungal cell, causing cell death.
- Ketoconazole acts by interfering with the synthesis of ergosterol in the fungal cell membrane by inhibiting the cytochrome P450-dependent enzyme lanosterol 14-alpha-demethylase.
- The synergistic combination ensures higher efficacy against dermatophytes and yeasts, significantly reducing the likelihood of treatment failure or recurrence.
Key Benefits
- Provides dual-action antifungal coverage for resistant infections
- Effectively treats infections involving skin, hair, and nails
- Assists in the rapid resolution of stubborn fungal growth
- Reduces the risk of infection recurrence by targeting multiple pathways
- Offers a comprehensive oral solution for systemic fungal management
Precautions
Use Only Under Medical Supervision
- Terbiface Forte Tablet contains strong antifungal agents and should be taken only as prescribed by a doctor
- Do not self-medicate or change the dose without guidance
Liver Function Monitoring
- This medicine may affect liver function in some cases
- Regular liver function tests may be recommended during treatment
Avoid Alcohol Consumption
- Alcohol may increase the risk of liver toxicity
- It is advised to avoid alcohol during the treatment period
Inform About Medical Conditions
- Tell your doctor if you have liver, kidney, or heart problems
- Dose adjustment or monitoring may be required
Pregnancy and Breastfeeding
- Use only if clearly prescribed by a doctor
- Safety should be assessed before use
Complete Full Course
- Do not stop the medicine early even if symptoms improve
- Incomplete treatment may cause recurrence of infection
| Precaution Area | Guidance |
|---|---|
| Usage | Take only as prescribed by doctor |
| Liver Health | Regular monitoring may be required |
| Alcohol | Avoid during treatment |
| Medical Conditions | Inform doctor before use |
| Pregnancy | Use only if prescribed |
| Treatment Course | Complete full prescribed duration |
Usage
Dosage
Consume the tablet exactly as prescribed by your doctor to ensure effective eradication of the fungal infection
Maintain a consistent daily schedule to keep the necessary concentration of the medication in your system
Swallow the tablet whole with a sufficient amount of water
Adhere strictly to the recommended duration of the course, even if symptoms appear to subside early
Administration
Take the tablet preferably with a meal to enhance absorption and minimize potential gastric irritation
Avoid consumption of alcohol while on this medication to protect liver health
Monitor for any unusual side effects or signs of liver distress throughout the treatment period
Store the medication in its original packaging in a cool, dry environment away from direct sunlight
Treatment Administration Summary
| Protocol | Requirement |
| Frequency | Once daily or as directed by a physician |
| Intake Method | Swallow whole with water |
| Optimal Absorption | Administer with food |
| Safety Check | Report any signs of jaundice or stomach pain |
Uses
Treatment of dermatophyte infections including tinea corporis (ringworm) and tinea cruris (jock itch)
Eradication of chronic or resistant fungal infections affecting the nails (onychomycosis)
Management of systemic fungal and yeast infections
Prevention of recurrent fungal colonization through dual-action metabolic inhibition
Reduction of inflammatory responses resulting from active fungal activity
Side Effects
Common Side Effects
- Nausea or stomach upset
- Headache or dizziness
- Mild abdominal pain
- Loss of appetite
Skin Related Reactions
- Itching or skin rash in some cases
- Temporary skin sensitivity
Liver Related Effects
- Elevated liver enzymes in rare cases
- Signs of liver stress such as fatigue or dark urine (requires medical attention)
Gastrointestinal Issues
- Diarrhea or constipation
- Bloating or discomfort
Rare but Serious Effects
- Severe allergic reactions like swelling or difficulty breathing
- Persistent vomiting or jaundice (requires immediate medical help)
| Side Effect Type | Details |
|---|---|
| Common Effects | Nausea, headache, dizziness |
| GI Issues | Stomach pain, diarrhea, loss of appetite |
| Skin Reactions | Rash, itching |
| Liver Effects | Elevated enzymes, jaundice in rare cases |
| Serious Reactions | Severe allergy, persistent vomiting |
FAQs
Q: What is Terbiface Forte Tablet used for?
A: Terbiface Forte Tablet is used to treat a variety of fungal and yeast infections affecting the skin, nails, and scalp, such as tinea corporis, tinea cruris, and other resistant dermatological fungal conditions.
Q: Why is this a combination of two antifungal medicines?
A: Combining Terbinafine and Ketoconazole provides a broader and more robust antifungal effect. Each ingredient targets the fungal cell membrane through a different mechanism, which helps in eradicating stubborn infections and reducing the chance of recurrence.
Q: Can I stop taking the tablet once my skin looks better?
A: No, it is critical to complete the full course of treatment as prescribed by your healthcare provider. Stopping early can lead to incomplete eradication of the fungus, potentially causing the infection to return or become resistant to treatment.
Q: Should I take this medication with food?
A: Generally, taking this medication with food can help improve absorption and reduce the likelihood of stomach upset. Always follow the specific instructions provided by your doctor or pharmacist regarding intake.
Q: Are there any liver-related concerns with this medication?
A: Both ingredients can affect liver function. It is important to inform your doctor if you have a history of liver disease. Your physician may recommend regular blood tests to monitor your liver enzymes during the treatment period.
Q: What should I do if I experience symptoms like yellowing of eyes or skin?
A: These can be signs of liver issues. Stop taking the medication immediately and contact your healthcare provider or seek medical attention right away if you notice signs of jaundice, dark urine, or severe nausea.
Interactions
Other Antifungal Medicines
- Avoid using multiple antifungal tablets or creams together unless prescribed
- May increase risk of side effects or drug overlap
Liver Affecting Medicines
- Use caution with medicines that affect liver function such as certain antibiotics or cholesterol lowering drugs
- Regular monitoring may be required
Alcohol
- Avoid alcohol as it may increase the risk of liver toxicity
- Combination can strain liver function significantly
Blood Thinners and Cardiac Medicines
- May interact with certain anticoagulants and heart medicines
- Doctor supervision is necessary for dose adjustment
Enzyme Affecting Drugs
- Some medicines that affect liver enzymes may alter the effectiveness of Terbiface Forte Tablet
- Always inform your doctor about all ongoing medications
| Interaction Type | Recommendation |
|---|---|
| Other Antifungals | Avoid combination unless prescribed |
| Liver Affecting Drugs | Use with caution and monitoring |
| Alcohol | Strictly avoid |
| Blood Thinners | Use only under medical supervision |
| Enzyme Affecting Medicines | Inform doctor before use |
| Manufacturer | : | Healing Pharma |
| Trade Name | : | |
| Generic Search | : | Terbinafine + Ketoconazole |
| Strength | : | 250mg + 100mg |
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