Susten VT Tablet (Progesterone) | Used for Pregnancy Support and Fertility Care
Susten VT Tablet (Progesterone) a natural hormone used to support the uterine lining, prevent miscarriage, and treat progesterone deficiency in women. Used in assisted reproduction, luteal phase support, and hormone replacement therapy.
Product Overview
Susten VT Tablet is a specialized hormonal formulation containing Natural Micronised Progesterone, which is identical to the hormone naturally produced by the female body. Susten VT Tablet is primarily used to treat progesterone deficiency and various gynecological conditions including female infertility, irregular menstrual cycles, and hormone replacement therapy (HRT). By replenishing essential hormone levels, it plays a critical role in supporting the luteal phase and ensuring the successful maintenance of early pregnancy.
Product Composition
- Natural Micronised Progesterone: Available in strengths like 200mg, this bio-identical hormone is processed through micronization for enhanced absorption and better bioavailability.
- Vaginal Delivery System: Designed specifically as a vaginal tablet (VT) to provide localized action, minimizing systemic side effects while maximizing the concentration in the uterine tissue.
Product Specification
| Feature | Specification Details |
| Therapeutic Class | Progestogens / Female Sex Hormones |
| Active Ingredient | Micronised Progesterone |
| Administration Route | Vaginal Insertion |
| Common Strengths | 200 mg |
| Storage Requirements | Store in a cool, dry place away from direct sunlight |
Mechanism of Action
- Endometrial Transformation: Susten VT works by inducing secretory changes in the endometrium (uterine lining), making it receptive and stable for embryo implantation.
- Uterine Quiescence: It reduces the sensitivity of the uterus to contraction-inducing signals, effectively acting as a tocolytic agent to prevent preterm labor or threatened miscarriage.
- Hormonal Regulation: It balances the effects of estrogen, preventing endometrial hyperplasia (overgrowth of the uterine lining) and regulating the menstrual cycle in cases of secondary amenorrhoea.
- Cervical Mucus Modulation: It increases the viscosity of cervical mucus, which helps in maintaining a protective barrier during the gestational period.
Key Benefits
- Pregnancy Support: Essential for women undergoing Assisted Reproductive Technology (ART) or IVF, as it provides vital luteal phase support.
- Reduced Side Effects: Vaginal administration bypasses the first-pass metabolism in the liver, significantly reducing common oral progesterone issues like extreme drowsiness or nausea.
- Miscarriage Prevention: Helps in stabilizing the pregnancy environment for women with a history of recurrent pregnancy loss or progesterone insufficiency.
- Menstrual Regularity: Effectively treats irregular periods and absence of menstruation by restoring the natural hormonal rhythm.
- Hormone Balance: Provides a safe and effective component for menopause management when used alongside estrogen therapy.
Usage
Susten VT Tablet is designed for vaginal administration to ensure the medication is delivered directly to the uterine tissues. To achieve the best therapeutic results, the tablet should be inserted deep into the vaginal canal using the provided applicator or a clean finger. Following a consistent dosing schedule is vital for maintaining stable progesterone levels throughout the treatment cycle.
Application Timing: It is generally recommended to use the tablet at bedtime to maximize local absorption and reduce any potential discharge during daily activity.
Consistency: For luteal phase support in fertility treatments, the medication should be started on the specific day of the cycle advised by a specialist.
Hygiene Protocol: Always wash hands thoroughly before and after insertion to prevent vaginal infections.
Missed Dose: If a dose is missed, it should be inserted as soon as remembered, unless it is nearly time for the next scheduled dose; do not double the dose.
Uses
| Medical Indication | Description of Application |
| Female Infertility | Used to prepare the uterine lining for embryo implantation during natural or assisted cycles. |
| Assisted Reproductive Technology (ART) | Provides critical progesterone supplementation during IVF or IUI procedures. |
| Threatened Miscarriage | Helps stabilize the pregnancy in women experiencing vaginal bleeding or early pregnancy complications. |
| Amenorrhoea | Treats the absence of periods by inducing withdrawal bleeding in women with hormonal imbalances. |
| Hormone Replacement Therapy (HRT) | Prevents endometrial thickening in menopausal women receiving estrogen replacement. |
Targeted Therapeutic Applications
Luteal Phase Support: Essential for maintaining the secretory endometrium after ovulation, which is necessary for the survival of the early embryo.
Preterm Birth Prevention: Prescribed for women with a short cervix or a history of spontaneous premature labor to help prolong the pregnancy.
Recurrent Pregnancy Loss: Used as a preventive measure for patients who have suffered multiple spontaneous abortions due to low progesterone.
Endometrial Protection: Acts as a counter-balance to estrogen to ensure the health of the uterine lining and prevent abnormal tissue growth.
Cycle Regulation: Helps in managing dysfunctional uterine bleeding and restoring a predictable menstrual flow.
Side Effects
Possible Side Effects of Susten VT Tablet (Progesterone)
Susten VT Tablet may cause side effects in some users. Most are mild and improve as the body adjusts to hormonal changes. Some effects may need medical attention if they persist or worsen.
Common Side Effects
- Vaginal irritation or discomfort
- Mild headache
- Breast tenderness
- Bloating
- Mood changes
- Mild abdominal cramps
Less Common Side Effects
- Drowsiness or tiredness
- Dizziness
- Mild nausea
- Fluid retention
- Increased vaginal discharge
- Mild spotting or irregular bleeding
| Rare Side Effects | Details |
|---|---|
| Severe allergic reaction | Swelling, rash, itching, or breathing difficulty |
| Severe mood changes | Depression or significant mood swings |
| Blood clot symptoms | Pain, swelling in legs, or sudden chest discomfort |
| Severe liver issues | Yellowing of skin or eyes |
| Severe vaginal irritation | Burning, pain, or persistent discomfort |
When to Seek Medical Attention
Seek immediate help if you notice severe allergic reactions, signs of blood clots, or unusual heavy bleeding. Persistent or worsening symptoms should also be evaluated.
FAQs
Q: What is Susten VT Tablet?
A: Susten VT Tablet contains Progesterone, a natural female hormone. It is a vaginal tablet used to supplement or replace progesterone in women when the body does not produce enough of it naturally.
Q: What is the product used for?
A: Susten VT Tablet is used to support the uterine lining, prevent miscarriage, provide luteal phase support in assisted reproduction (IVF), treat abnormal uterine bleeding, and as part of hormone replacement therapy (HRT).
Q: How does it work?
A: Progesterone prepares and maintains the lining of the uterus (endometrium) for a fertilized egg. It also prevents the uterus from contracting prematurely and supports early pregnancy until the placenta takes over hormone production.
Q: How is it used?
A: It is inserted directly into the vagina as directed by the doctor. Hands should be washed before insertion and the tablet should be placed as deep into the vagina as comfortable using a finger or the applicator provided.
Q: How long is the course?
A: The duration depends on the condition being treated. In IVF support it is typically used for 10 to 12 weeks. Always follow the doctor's prescribed duration and never stop without medical advice.
Q: Who should not use it?
A: Women with unexplained vaginal bleeding, a history of blood clots, liver disease, known or suspected breast or genital cancer, or allergy to progesterone should not use this tablet without medical consultation.
Q: What are the common side effects?
A: Common side effects include vaginal irritation or discharge, bloating, breast tenderness, mild dizziness, headache, and mood changes. These are generally mild and temporary.
Q: Is it safe during pregnancy?
A: Yes, it is often prescribed during early pregnancy to prevent miscarriage and support the developing pregnancy. However, it should only be used under strict medical supervision.
Q: Can it be used during breastfeeding?
A: It is generally not recommended during breastfeeding. Consult your doctor before use if you are nursing.
Q: What should I do if I miss a dose?
A: Insert the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed one and continue with the regular schedule. Do not use a double dose to make up for the missed one.
Q: Can Susten VT be used alongside other medicines?
A: Inform your doctor about all medications you are currently taking as progesterone may interact with certain drugs including blood thinners, antifungals, and some antibiotics.
Q: How should it be stored?
A: Store in a cool, dry place away from direct sunlight and heat. Keep out of reach of children. Check the packaging for specific storage temperature instructions.
| Manufacturer | : | Sun Pharma, India |
| Trade Name | : | Prometrium |
| Generic Search | : | Progesterone |
| Strength | : | 200 mg |
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