Hyocimax-S Tablet (Hyoscyamine) | Used for Irritable Bowel Syndrome and Gastrointestinal Disorders
Hyocimax-S Tablet (Hyoscyamine) is a medication used primarily to treat a variety of conditions involving gastrointestinal disorders, bladder spasms, and other related symptoms.
Product Overview
Hyocimax-S Tablet is a highly effective, immediate-release antispasmodic and anticholinergic medication prescribed for the systemic management of functional gastrointestinal and visceral motility disorders. Containing the active therapeutic compound Hyoscyamine (as hyoscyamine sulfate), this oral tablet works by blocking the action of acetylcholine on smooth muscles and exocrine glands. Hyocimax-S is primarily utilized to provide targeted, day-to-day relief from painful cramps, spasms, and hyper-motility associated with conditions like irritable bowel syndrome (IBS), peptic ulcer disease, diverticulitis, and acute bladder spasms.
Product Composition
- Active Pharmaceutical Ingredient: Hyoscyamine Sulfate (typically formulated at 0.125mg per oral tablet)
- Dosage Form: Small, solid immediate-release oral tablets designed for rapid gastrointestinal disintegration and systematic absorption
- Core Excipients: Formulated with standard pharmaceutical-grade binders, including lactose monohydrate, microcrystalline cellulose, and magnesium stearate
Product Specification
| Product Parameter | Details |
| Brand Name | Hyocimax-S Tablet |
| Active Ingredient | Hyoscyamine Sulfate |
| Therapeutic Class | Anticholinergics / Antispasmodics (Belladonna alkaloids) |
| Available Strength | 0.125mg |
| Primary Indications | Irritable Bowel Syndrome (IBS), functional GI disorders, neurogenic bladder spasms, and adjunctive peptic ulcer therapy |
Mechanism of Action
- Muscarinic Receptor Antagonism: Hyoscyamine works as a competitive inhibitor of acetylcholine at postganglionic muscarinic receptors located on smooth muscle cells and exocrine secretory glands.
- Smooth Muscle Relaxation: By preventing acetylcholine from binding, it suppresses parasympathetic nerve impulses, directly relaxing hyperactive smooth muscle tissue along the stomach, intestinal walls, and urinary bladder.
- Secretory Suppression: This antagonist action simultaneously downregulates the overproduction of gastric acid, salivary fluids, and bronchial secretions, while moderating overall gastrointestinal transit speed.
Key Benefits
- Provides highly targeted relief from chronic abdominal pain, cramping, and painful visceral spasms associated with functional bowel disorders.
- Features an immediate-release oral formulation that allows for flexible, symptom-driven dosing schedules under medical guidance.
- Functions effectively as an adjunctive treatment to control painful gastric hyper-secretion and hyper-motility in patients with peptic ulcers.
- Helps stabilize an overactive bladder by reducing the frequency and intensity of urgent neurogenic smooth muscle contractions.
Precautions
Important Precautions for Hyocimax-S Tablet (Hyoscyamine)
Hyocimax-S Tablet is used for abdominal cramps and gastrointestinal spasms. It should be used carefully due to its anticholinergic effects.
| Precaution Area | Details |
|---|---|
| Heart Conditions | May increase heart rate. |
| Glaucoma | Can worsen eye pressure. |
| Urinary Issues | May cause difficulty in urination. |
| Elderly Patients | Higher risk of confusion. |
| Heat Sensitivity | May reduce sweating. |
| Digestive Blockage | Avoid in intestinal obstruction. |
| Liver or Kidney Issues | Use with caution. |
Important Safety Advice
- Take only as prescribed
- Avoid alcohol during use
- Do not exceed recommended dose
- Stay hydrated during treatment
- Report vision changes or confusion
When to Avoid Hyocimax-S Tablet
- Narrow-angle glaucoma
- Severe urinary retention
- Intestinal obstruction
- Known allergy to Hyoscyamine
Monitoring Requirements
- Heart rate monitoring if needed
- Mental status check in elderly patients
- Eye pressure evaluation in at-risk patients
- Response to spasm relief therapy
General Note
- Elderly patients are more sensitive to side effects
- Use short-term unless advised otherwise
- Report persistent or severe symptoms promptly
Usage
This low-dose oral antispasmodic requires careful, systematic dosing to achieve optimal symptom control while minimizing side effects. Dosage schedules should be individualized based on the patient's age and clinical response. For maximum therapeutic benefit, tablets should be taken ahead of triggers like meals. Patients must be monitored closely for signs of anticholinergic toxicity, particularly elderly individuals who are more vulnerable to central nervous system effects such as confusion or dizziness.
| Parameter | Clinical Guidelines |
| Standard Dosage | The typical adult dose is 1 to 2 tablets (0.125mg to 0.25mg) taken every 4 hours or as needed. Do not exceed a maximum of 12 tablets (1.5mg) in any 24-hour period. |
| Administration Route | For oral use only. Swallow the tablets with a full glass of water. They can be taken with or without food, though taking them 30 to 60 minutes before meals optimizes spasm prevention. |
| Dosing Consistency | For chronic conditions like IBS, it is best taken on a regular schedule as directed by a doctor. If a dose is missed, take it as soon as remembered, but skip it if it is almost time for the next scheduled dose. |
| Anhidrosis Warning | Because this drug reduces sweating, it can impair the body's ability to regulate temperature. Avoid strenuous physical activity or prolonged exposure to high heat to prevent heat stroke and hyperthermia. |
Uses
Management of Irritable Bowel Syndrome (IBS): Indicated for the symptomatic control of functional gastrointestinal tract disorders, specifically reducing painful abdominal cramping, spasms, and hyper-motility.
Adjunctive Therapy for Peptic Ulcers: Utilized alongside standard acid-suppressing therapies to reduce gastric acid secretions and decrease painful smooth muscle contractions in the stomach lining.
Control of Neurogenic Bladder Disorders: Prescribed to relieve hyper-motility, urgency, and painful muscle spasms of the urinary bladder caused by underlying neurological conditions or infections.
Symptomatic Relief of Diverticulitis: Employed to alleviate painful localized colonic spasms and associated discomfort during mild, uncomplicated flare-ups of diverticular disease.
Side Effects
Possible Side Effects of Hyocimax-S Tablet (Hyoscyamine)
Hyocimax-S Tablet may cause side effects due to its antispasmodic and anticholinergic action. Most effects are mild and temporary, but some may need medical attention.
| Side Effect Type | Details |
|---|---|
| Common Effects | Dry mouth, dizziness. |
| Eye Effects | Blurred vision, sensitivity to light. |
| Heart Effects | Increased heart rate. |
| Digestive Effects | Constipation, nausea. |
| Urinary Effects | Difficulty in urination. |
| Nervous System | Confusion or drowsiness (especially in elderly). |
Common Side Effects
- Dry mouth
- Dizziness
- Constipation
- Mild blurred vision
Less Common But Important Effects
- Fast heartbeat
- Difficulty urinating
- Confusion or restlessness
- Increased sensitivity to light
When to Be Careful
- Severe confusion or agitation
- Persistent blurred vision
- Severe constipation or abdominal pain
- Difficulty passing urine
General Note
- Elderly patients are more sensitive to side effects
- Effects are usually dose related
- Report persistent or severe symptoms promptly
FAQs
Q: What is Hyocimax-S Tablet used for?
A: This oral antispasmodic medication is primarily prescribed to provide relief from painful cramps, spasms, and hyper-motility associated with functional bowel disorders like Irritable Bowel Syndrome (IBS). It is also used as an adjunctive therapy for peptic ulcers and to control neurogenic bladder spasms.
Q: How should Hyocimax-S Tablets be taken?
A: This medication is for oral use and is typically taken 30 to 60 minutes before meals and at bedtime. It can be taken with or without food, but taking it before meals helps maximize its ability to prevent eating-induced intestinal spasms.
Q: How does Hyoscyamine reduce abdominal cramping?
A: It functions as a competitive muscarinic receptor antagonist. By blocking acetylcholine from binding to receptors on smooth muscle walls, it dampens parasympathetic nerve signals, which relaxes the cramped muscles of the stomach, intestines, and bladder.
Q: Can this medication cause blurred vision and dry mouth?
A: Yes, these are classic anticholinergic side effects. Blocking acetylcholine reduces salivary secretions, leading to dry mouth (xerostomia), and can cause temporary blurred vision by dilating the pupils. Drinking water or sucking on sugarless lozenges can help ease mouth dryness.
Q: What conditions make Hyocimax-S Tablets unsafe to use?
A: It is strictly contraindicated in patients with narrow-angle glaucoma, as it can increase intraocular pressure. It must also be avoided by individuals with urinary retention, severe prostatic hypertrophy, myasthenia gravis, or severe gastrointestinal obstructions like paralytic ileus.
Q: What precautions should be taken when exercising or in hot weather?
A: Hyoscyamine suppresses the activity of sweat glands, making it harder for the body to cool down. Patients must exercise caution in hot weather or during heavy physical exertion to avoid heatstroke, heat prostration, or developing a high fever (hyperthermia).
Interactions
Drug Interactions of Hyocimax-S Tablet (Hyoscyamine)
Hyocimax-S Tablet may interact with medicines that have anticholinergic or central nervous system effects. These combinations can increase side effects such as dryness, confusion, and fast heart rate.
| Medicine or Product Type | Interaction Details |
|---|---|
| Antihistamines | Increased dryness and drowsiness. |
| Antidepressants | Enhanced anticholinergic effects. |
| Antipsychotics | May increase confusion and sedation. |
| Other Antispasmodics | Increased side effect risk. |
| Opioid Painkillers | More constipation and drowsiness. |
| Muscle Relaxants | Increased weakness and sedation. |
Important Interaction Advice
- Avoid combining multiple anticholinergic medicines
- Inform about all ongoing prescription medicines
- Use caution with sedatives or sleep medicines
- Monitor for confusion, dry mouth, or palpitations
General Guidance
- Elderly patients need closer monitoring
- Dose adjustments may be required in combination therapy
- Avoid self-medication with similar symptom drugs
- Report severe dizziness or mental confusion
Additional Note
- Always share complete medication history before starting Hyocimax-S Tablet to avoid harmful interactions
| Manufacturer | : | Zydus Cadila |
| Trade Name | : | Levsin |
| Generic Search | : | Hyoscyamine |
| Strength | : | 0.125mg |















