Enclomisign 50 mg (Enclomiphene Citrate) | Used to Treat infertility in Male & Female
Enclomisign 50 mg Tablets (Enclomiphene Citrate) are used under medical supervision to support fertility and hormonal balance in men and women. In men, it helps increase natural testosterone levels, while in women it may support ovulation and reproductive hormone balance.
Product Overview
Enclomisign 50 mg Tablets (Enclomiphene Citrate) is used to support reproductive hormone balance and fertility in both men and women under medical supervision. It is primarily indicated for the treatment of male hypogonadism (low testosterone levels) and male infertility by stimulating the body’s natural testosterone production and improving sperm quality. In women, it may be used in selected cases to support ovulation and assist in the management of certain fertility-related conditions.
Unlike direct hormone replacement therapies, Enclomiphene works by enhancing the body’s own hormonal signaling system, helping restore normal reproductive function through stimulation of the hypothalamic-pituitary-gonadal (HPG) axis.
Product Composition
- Active Ingredient: Enclomiphene Citrate
- Strength: 50 mg
- Dosage Form: Oral Tablet
- Pharmacological Class: Selective Estrogen Receptor Modulator (SERM)
Product Specification
| Feature | Details |
| Primary Indication | Male hypogonadism, male infertility; ovulation support in females (selected cases) |
| Target Use | Hormonal imbalance and fertility enhancement |
| Route of Administration | Oral |
| Storage | Store in a cool, dry place away from moisture and direct sunlight |
| Patient Group | Adult men and women under medical supervision |
Mechanism of Action
- Acts as a selective estrogen receptor modulator (SERM)
- Blocks estrogen feedback at the hypothalamus and pituitary gland
- Increases release of gonadotropins (LH and FSH)
- In men, stimulates testes to produce natural testosterone
- In women, supports follicular development and ovulation
- Helps restore natural endocrine balance without external hormone replacement
Key Benefits
- Supports natural testosterone production in men
- Improves sperm count and sperm quality in male infertility
- May help induce ovulation in selected female infertility cases
- Restores hormonal balance through natural stimulation pathways
- Non-steroidal fertility support option
- Useful in managing secondary hypogonadism and reproductive hormone disorders
Usage
Dosage and Administration
- Take Enclomisign 50 mg Tablets exactly as prescribed by your doctor
- Usually taken once daily at the same time each day for consistent hormonal effect
- Can be taken with or without food
- Swallow the tablet whole with water
- Do not skip doses or take extra doses without medical advice
Administration Guidelines
| Scenario | Recommendation |
|---|---|
| Missed Dose | Take it as soon as remembered. If it is close to the next dose, skip the missed dose |
| Overdose | Seek immediate medical attention and do not self-medicate |
| Duration of Use | Determined by doctor based on hormone levels and treatment response |
| Monitoring | Regular tests for testosterone, LH, and FSH may be required |
| Storage | Store at room temperature, away from moisture, heat, and direct sunlight |
Uses
Treatment of Male Hypogonadism
- Used to treat low testosterone levels in men
- Stimulates the body’s natural testosterone production
- Helps improve energy, mood, libido, and overall well-being
Male Infertility Management
- Improves sperm count and sperm quality
- Supports natural fertility without external testosterone replacement therapy
- Used in infertility caused by hormonal imbalance
Female Ovulation Support (Selected Cases)
- May help stimulate ovulation in women under specialist supervision
- Used in fertility treatment protocols for selected patients
- Helps regulate reproductive hormone function
Hormonal Regulation Support
- Supports balance of the hypothalamic-pituitary-gonadal axis
- Helps restore natural reproductive hormone signaling
- Improves overall endocrine and reproductive function in appropriate cases
Side Effects
Enclomisign 50 mg Tablets (Enclomiphene Citrate) is generally well tolerated when used under medical supervision, but some patients may experience side effects, especially during the initial phase of treatment.
Common Side Effects
- Headache
- Nausea
- Hot flushes
- Mood changes or irritability
- Dizziness
- Fatigue
Less Common Side Effects
- Blurred vision or visual disturbances
- Breast tenderness or discomfort
- Acne or oily skin
- Abdominal discomfort
- Sleep disturbances
Serious Side Effects
| Serious Condition | Symptoms |
|---|---|
| Vision problems | Persistent blurred vision, flashes of light, or visual loss |
| Blood clots | Swelling, pain in legs, chest pain, or shortness of breath |
| Severe hormonal imbalance | Extreme mood changes, persistent fatigue, or libido changes |
| Liver issues | Yellowing of skin/eyes, dark urine, severe abdominal pain |
| Allergic reaction | Rash, swelling of face/lips/tongue, difficulty breathing |
Important Advice
- Report any persistent vision changes immediately to your doctor
- Do not continue the medicine if severe side effects occur without medical advice
- Regular hormone and health monitoring may be required during treatment
- Avoid self-adjusting the dose or combining with other hormone therapies
- Seek urgent medical help for chest pain, breathing difficulty, or signs of blood clots
Interactions
Drug Interactions
| Medicine / Drug Class | Interaction Effect |
|---|---|
| Estrogen-containing medicines | May reduce effectiveness of Enclomiphene Citrate |
| Testosterone therapy or anabolic steroids | Can suppress natural hormone stimulation and reduce benefits |
| Corticosteroids | May interfere with hormonal regulation and treatment response |
| Thyroid medications | May alter hormonal balance and require monitoring |
| Anticoagulants (blood thinners) | Possible increased risk of bleeding; requires caution |
Food and Lifestyle Interactions
- Alcohol may reduce hormonal balance and affect liver function
- Smoking may negatively impact fertility outcomes and treatment response
- Poor diet or obesity can reduce effectiveness in improving hormone levels
Disease Interactions
- Liver disease may alter drug metabolism and increase side effects
- Pituitary disorders may affect hormone response and require specialist evaluation
- History of blood clots may increase risk of complications during therapy
Important Clinical Considerations
- Always inform your doctor about all ongoing medications and supplements
- Hormone levels should be regularly monitored during treatment
- Avoid combining with other fertility or hormone therapies without medical advice
- Dose adjustments may be required based on response and lab results
- Report symptoms like vision changes, severe headache, or unusual fatigue immediately
| Manufacturer | : | Signature Pharmaceuticals |
| Trade Name | : | Androxal |
| Generic Search | : | Enclomiphene |
| Strength | : | 50 mg |























