Alphadopa Tablet (Methyldopa)

Introduction of Methyldopa Tablet (Alphadopa)

Methyldopa Tablet, commonly known by the brand name Alphadopa, is a medication primarily used to treat high blood pressure (hypertension) during pregnancy. It belongs to a class of medications called centrally-acting alpha-2 adrenergic agonists. Methyldopa works by relaxing and dilating the blood vessels, thereby reducing the pressure exerted on the walls of the arteries. This helps to lower blood pressure and improve blood flow throughout the body. Alphadopa is available in tablet form and is usually taken orally. It is also sold under the brand name Aldomet.

Uses of Methyldopa Tablet (Alphadopa)

Methyldopa is used to treat high blood pressure (hypertension).

How it works

Methyldopa (Aldomet) belongs to a group of medicines called antihypertensives. It reduces elevated blood pressure by relaxing and dilating (widening) blood vessels.

Methyldopa Tablet Benefits:

Methyldopa Tablet (Alphadopa) offers several benefits in the management of hypertension during pregnancy. It effectively lowers blood pressure, reducing the risk of complications associated with high blood pressure in expectant mothers. By relaxing and dilating blood vessels, Methyldopa improves blood flow, which can help maintain a healthy environment for the developing fetus. With its proven safety profile, Methyldopa is a trusted choice for healthcare providers to address hypertension in pregnant women.

Precautions of Methyldopa Tablet (Alphadopa)

• Methyldopa (Aldomet) is specifically prescribed for hypertension during pregnancy. It is considered safe to use during this period, as it has been extensively studied and shown to be effective in reducing blood pressure without causing harm to the developing fetus. However, it is important to follow your doctor's instructions and inform them if you become pregnant or plan to become pregnant while taking Alphadopa.
• Methyldopa can pass into breast milk but is generally considered safe to use while breastfeeding. However, it is recommended to consult with your healthcare provider before taking Alphadopa if you are breastfeeding.
• If you have a history of liver disease or any liver-related conditions, it is important to inform your doctor before starting Methyldopa treatment. Close monitoring of liver function may be required during the course of therapy.
• Methyldopa may worsen symptoms of depression or other psychiatric disorders. If you have a history of these conditions, it is important to discuss this with your doctor before initiating Alphadopa therapy.
  
  

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Common side effects of Methyldopa Tablet (Aldomet)

Abnormal production of milk, Uncontrollable movements, Abnormal blood test, Abdominal pain, Headache or feeling weak, Frequent dizziness or fainting, Swelling of salivary glands, Pins, and needles, Changes in sexual function such as impotence and not being able to ejaculate, Breast development in men, Confusion, Low hemoglobin or red blood cells, Loss of periods in women, Oral Preparations, Bruising and prolonged bleeding after injury, Constipation, Excess wind, Dizziness due to low blood pressure and light-headedness, Including nightmares or depression, Sore or black tongue, Diarrhea, Paralysis, Feeling bloated, Muscle pains, Dry mouth, Vomiting, Water retention causing swelling and weight gain

Expert advice

• Do not take methyldopa if you ever had or have any allergy to methyldopa, or to any of the other ingredients.
• Avoid taking methyldopa if you have high blood pressure due to a tumor near your kidney called ‘phaeochromocytoma’.
• Do not take methyldopa if you have liver or kidney disease, or depression.
• Do not take methyldopa if you are pregnant, planning to become pregnant, or breastfeeding.
• Do not drive or use any tools or machines as you may feel drowsy or light-headed while taking methyldopa.
• Do not drink alcohol while you are using methyldopa.
• Methyldopa may affect the results of certain laboratory tests: regular checks (before the start of treatment and 6-12 weeks later) may be carried out on blood cells and liver function.

Frequently asked questions

Methyldopa (Aldomet)

Q. Is methyldopa a beta blocker/ blood thinner/ diuretic/ calcium channel blocker?

Methyldopa is an alpha-2 receptor agonist. It is not a beta blocker, blood thinner, diuretic, or calcium channel blocker.

Q. Can I take ibuprofen/ paracetamol/ aspirin/ melatonin with methyldopa?

Methyldopa is known to interact with NSAIDs such as ibuprofen, paracetamol, and aspirin. However, there is no known interaction with melatonin. Always consult your doctor regarding its use.

Q. Does methyldopa cause weight gain/ make you tired/ lower heart rate/ hair loss/ birth defects/ dry mouth/ swelling?

Methyldopa is known to cause tiredness, dry mouth, and swelling. However, it does not cause weight gain, lower heart rate, cause birth defects. Please consult your doctor if you experience such side effects.

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Drug interaction with Methyldopa Tablet (Alphadopa)

• Methyldopa can potentiate the effects of other antihypertensive medications, such as beta-blockers, diuretics, calcium channel blockers, and ACE inhibitors. Combining these drugs with Methyldopa may lead to excessive blood pressure reduction, resulting in hypotension (low blood pressure). Your doctor will carefully adjust the dosages to avoid such interactions.
• Concomitant use of Methyldopa with MAOIs, a class of antidepressant medications, may result in an intensified antihypertensive response. This combination should be avoided due to the increased risk of severe hypotension.
• Certain antidepressant medications, such as tricyclic antidepressants (TCAs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), may interact with Methyldopa. The combination of these medications with Methyldopa (Aldomet) can increase the risk of side effects, including sedation, drowsiness, and orthostatic hypotension.
• Methyldopa may diminish the effectiveness of levodopa, a medication used in the treatment of Parkinson's disease. Therefore, concurrent use of Methyldopa with levodopa should be avoided or closely monitored by your healthcare provider.
• NSAIDs, such as ibuprofen and naproxen, can reduce the antihypertensive effects of Methyldopa. It is recommended to use caution when combining Methyldopa with NSAIDs and monitor blood pressure closely.
• Alcohol consumption should be avoided or limited while taking Methyldopa. Alcohol can increase the sedative effects of Methyldopa, leading to excessive drowsiness and dizziness.