Xeloda Tablet (Capecitabine)

Introducyion of Xeloda Tablet (Capecitabine)

Capecitabine chemotherapy

Capecitabine, also known by its brand name Xeloda, is an oral chemotherapy medication that is commonly used in the treatment of various types of cancer, including breast cancer. It belongs to a class of drugs called fluoropyrimidines and is a prodrug that gets converted into its active form, 5-fluorouracil (5-FU), within the body. This medication is prescribed by healthcare professionals to inhibit the growth and spread of cancer cells.

Dosage Information:

The dosage of Capecitabine tablets can vary depending on the specific type of cancer being treated, the patient's body surface area, and other individual factors. It is important to follow the instructions provided by your healthcare provider regarding the dosage and duration of treatment. Typically, Capecitabine is taken orally twice a day, within 30 minutes after a meal, with a full glass of water. The tablets should be swallowed whole and not crushed, chewed, or split. The exact dosage will be determined by your doctor, but it is usually based on your body surface area, which is calculated using your height and weight. It is crucial to adhere to the prescribed schedule and dosage of Capecitabine. If you miss a dose, do not double the dose to make up for it. Take the next scheduled dose as usual and consult your healthcare provider for further guidance.

Uses of Xeloda Tablet (Capecitabine)

Capecitabine for breast cancer: Xeloda is commonly used in the treatment of metastatic breast cancer, where cancer has spread to other parts of the body. It is also employed as adjuvant therapy following surgery, radiation, or both, in patients with early-stage breast cancer with lymph node involvement.

Colorectal Cancer: Xeloda is prescribed for both colon cancer and rectal cancer. It can be administered as a single agent or in combination with other chemotherapy drugs. Xeloda is often used in the treatment of advanced or metastatic colorectal cancer when other treatment options have been exhausted.

Other Indications: In addition to breast and colorectal cancer, Xeloda may be employed in the treatment of other malignancies, including stomach cancer, pancreatic cancer, and gastric/esophageal cancer. However, the usage of Xeloda for these types of cancer may vary, and it is important to consult with a healthcare professional for specific treatment recommendations.

Capecitabine cost: At our online pharmacy, we offer the convenience of checking the cost of Capecitabine. We understand the financial considerations that come with cancer treatment, and we aim to provide transparency and accessibility to our customers. By visiting our website, you can easily access information on the cost of Capecitabine and make informed decisions regarding your treatment. Our online platform ensures a hassle-free experience, allowing you to compare prices, find cost-effective options, and order your medication with ease. We prioritize your well-being and strive to provide affordable solutions to help you on your journey toward recovery.

How it works

Capecitabine belongs to a class of medication called cytostatic agents which is an antineoplastic/ anticancer prodrug (gets converted into an active substance once in the body). Capecitabine, after being absorbed by the body changes into an active anticancer agent which is more active in the tumor tissue cells than in the normal cells, and thus, stops the growth of cancer cells and slows down the spread of cancer in the body.

Common side effects

Bleeding from the gut; red or itchy or dry or discolored skin, chest or back; shortness of breath or dry, skin inflammation, indigestion, nausea, loss of hair, cold sores or other herpes infection ., dehydration, nail disorder, skin loss, bleeding nose, a decrease of red and white blood cells in the blood, depression, dryness or irritation in eyes, constipation, excess wind, loss of appetite, tingling sensation on the skin; change in taste or dry mouth, limbs, diarrhea, Tiredness, fever and swelling in joints; pain in joints, increased bilirubin level; inflammation of a vein, lack of sleep, dizziness, runny, infection in lungs or bronchitis; problems with liver function, loss of weight, pain in the stomach, headache

Precautions of Xeloda Tablet (Capecitabine)

• Before starting Capecitabine treatment, it is essential to inform your doctor about any pre-existing medical conditions, including liver problems, kidney problems, heart disease, compromised immune system, or a history of certain medical conditions.
• Capecitabine may cause a decrease in blood cell counts, leading to an increased risk of infection, anemia, or bleeding. Regular blood tests will be conducted to monitor your blood cell counts during treatment.
• It is crucial to avoid pregnancy while taking Capecitabine, as it may cause harm to the unborn baby. Both males and females should use effective contraception during treatment and for a certain period afterward, as advised by their healthcare provider.
• Capecitabine may cause hand-foot syndrome, which is characterized by redness, swelling, and pain on the palms of the hands and soles of the feet. Inform your doctor if you experience any such symptoms, as they may recommend appropriate management strategies.
• During Capecitabine treatment, it is important to maintain good oral hygiene and take measures to prevent mouth sores. Avoid spicy, acidic, or rough foods and maintain proper oral care practices.
• Capecitabine can suppress the immune system, making you more susceptible to infections. Avoid close contact with individuals who have contagious illnesses, and promptly report any signs of infection to your healthcare provider.

Expert advice

• Capecitabine should be taken with water within half an hour of taking a meal.
• Inform your doctor if you are suffering from high or low levels of calcium, cardiac toxicity problems or hand and foot syndrome.
• Inform your doctor if you have a history of diabetes, nervous system disorders or are taking medication for blood thinning.
• Inform your doctor if you are taking any medications for gout (allopurinol), fits (phenytoin), or cancer (folinic acid, oxaliplatin, or bevacizumab).
• Capecitabine may cause dizziness or nausea and so it is recommended not to drive or use heavy machinery immediately after taking it.
• Treatment with capecitabine needs to be permanently discontinued in patients who experience a severe skin reaction.
• Women who are planning to become pregnant should use two methods of contraception while on this therapy and thereafter as recommended by the doctor.
• Men who are going to use this therapy should not father a child while on this therapy and thereafter as recommended by the doctor. They should also seek guidance and counseling on sperm conservation before taking this therapy.

Drug Interactions with Xeloda Tablet (Capecitabine)

Capecitabine can interact with other medications, potentially affecting its efficacy or increasing the risk of side effects. Inform your doctor about all the medications you are currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. Some medications that may interact with Capecitabine include:

Anticoagulants (blood thinners): Capecitabine may enhance the effects of anticoagulants, increasing the risk of bleeding.

Warfarin: Capecitabine may increase the concentration of warfarin in the blood, leading to an increased risk of bleeding.

Sorivudine or its analogs: Concurrent use of Capecitabine with sorivudine or its analogs is contraindicated, as it may cause severe toxicity.

Phenytoin and phenobarbital: These medications may reduce the effectiveness of Capecitabine.

Frequently asked questions

Xeloda Tablet (Capecitabine)

Q. Is capecitabine safe during pregnancy?

Capecitabine may harm the baby. It should only be given if there is no other alternative drug. Please follow your doctor's advice regarding its use.

Q. Is it safe to use capecitabine during breastfeeding?

Capecitabine is not safe during breastfeeding. It should only be used if no other alternative drug is available. Please follow your doctor's advice regarding its use.

Q. Is capecitabine a generic/ effective/FDA-approved?

Yes, capecitabine is a generic. It is approved by the FDA. It is effective when taken for a condition at a dose for the duration prescribed by the doctor.

Q. Is capecitabine an anthracycline?

No, capecitabine is not an anthracycline.

Q. Is capecitabine cytotoxic? How is it administered?

No. Capecitabine is a cytostatic (stops the growth of cells) agent. It is administered as a tablet.

Q. Where is capecitabine absorbed? How is it metabolized?

Capecitabine is quickly absorbed from the gastrointestinal tract. It is metabolized in the liver and tumor tissue.

Q. How quickly does capecitabine work? How long does it stay in the system?

Capecitabine works based on the intensity and severity of cancer. Please ask the doctor how quickly it will work. Capecitabine and its metabolites stay in the system for about two hours on average.

Q. Does capecitabine cause hair loss/ tiredness/ diarrhea or affect the skin?

Capecitabine is known to have side effects like hair loss/ tiredness/ diarrhea and affects the skin. Please inform the doctor about any side effects that you observe while on therapy.