Selgin Tablet (Selegiline) Used to Treat Symptoms of Parkinson Disease & Major Depressive Disorder
Selgin Tablet (Selegiline) is a medicine used to treat Parkinson’s disease by improving movement control and reducing symptoms such as stiffness and tremors.
Introduction
Selgin Tablet contains Selegiline, a medication that belongs to the class of monoamine oxidase type B (MAO-B) inhibitors. It is primarily prescribed for the treatment of Parkinson’s disease and major depressive disorder (MDD). Selgin works by increasing the levels of certain brain chemicals (dopamine, serotonin, norepinephrine), helping to improve movement control in Parkinson’s and mood in depression.
Precautions of Selgin Tablet (Selegiline)
- Avoid in patients with severe liver disease or peptic ulcer.
- Do not use with other MAO inhibitors or within 14 days of stopping them.
- Avoid high-tyramine foods (aged cheese, cured meats) to prevent dangerous blood pressure spikes.
- Use with caution in patients with cardiovascular disease or psychiatric disorders.
- Inform your doctor if pregnant, planning pregnancy, or breastfeeding.
- Avoid alcohol and activities requiring alertness if dizziness occurs.
Uses of Selgin Tablet (Selegiline)
Selgin Tablet is used for:
- Parkinson’s Disease – As monotherapy in early stages or in combination with levodopa in later stages to improve motor symptoms.
- Major Depressive Disorder (MDD) – In specific formulations, for patients not responding to other antidepressants.
- Other conditions – As prescribed by the physician.
Side Effects of Selgin Tablet (Selegiline)
Common side effects:
- Nausea or stomach upset
- Dizziness or lightheadedness
- Dry mouth
- Headache
- Insomnia
Serious but less common side effects:
- Severe hypertension (especially with high-tyramine foods)
- Hallucinations or confusion
- Irregular heartbeat
- Muscle stiffness or uncontrollable movements
- Signs of serotonin syndrome (fever, agitation, rapid heartbeat)
Seek immediate medical attention if any severe reaction occurs.
FAQs of Selgin Tablet (Selegiline)
Q1: How long does Selgin take to work in Parkinson’s disease?
Improvement in symptoms may be seen within a few weeks, but full benefits develop over time.
Q2: Can I take Selgin with antidepressants?
Only under strict medical supervision, as dangerous interactions may occur.
Q3: What is the best time to take Selgin?
Usually in the morning to avoid insomnia, unless prescribed otherwise.
Q4: Is dietary restriction necessary with Selgin?
At prescribed doses for Parkinson’s, restrictions are minimal, but in higher antidepressant doses, a low-tyramine diet is essential.
Q5: Can I stop Selgin suddenly?
No. Stopping suddenly may worsen symptoms or cause withdrawal effects—consult your doctor before discontinuing.
Interactions of Selgin Tablet (Selegiline)
Selgin may interact with:
- SSRIs, SNRIs, TCAs – increased risk of serotonin syndrome.
- Meperidine, tramadol, methadone – risk of severe reactions.
- Sympathomimetic drugs (pseudoephedrine, ephedrine) – risk of hypertension.
- Levodopa – may require dosage adjustment.
- High-tyramine foods – can cause dangerous blood pressure increases.
| Manufacturer | : | A. Menarini India Pvt Ltdine HCL) |
| Trade Name | : | Emsam |
| Generic Search | : | Selegiline Hcl |
| Strength | : | 5 mg |











