Profenac Eye Drop 0.1% - 5ml (Diclofenac Sodium) Used to Treat Post-operative Eye Pain and Inflammation
Profenac Eye Drop 0.1% (5 ml) is a nonsteroidal anti-inflammatory ophthalmic solution used to relieve postoperative eye pain and inflammation. The active ingredient, Diclofenac Sodium, helps reduce swelling, redness, and discomfort following cataract surgery or other eye procedures. Available in a compact 5 ml bottle, it’s designed for precise dosing and easy administration. Use under medical supervision, and avoid contact with soft contact lenses while using this medication.
Profenac Eye Drop Product Overview
Profenac Eye Drop is a high-potency non-steroidal anti-inflammatory drug (NSAID) containing Diclofenac Sodium 0.1%. This specialized ophthalmic solution is formulated to inhibit the synthesis of prostaglandins, which are the primary biological mediators of ocular pain, redness, and swelling. It is a cornerstone of post-operative care, widely prescribed to manage inflammation following cataract surgery and to prevent miosis (pupil constriction) during surgical procedures. By providing targeted anti-inflammatory action without the side effects often associated with steroids, Profenac ensures a smoother and more comfortable ocular recovery.
Product Composition
- Active Ingredient: Diclofenac Sodium 0.1% w/v (Non-Steroidal Anti-Inflammatory Drug).
- Preservative: Contains Benzalkonium Chloride (or as specified by the manufacturer) to maintain solution sterility.
- Pharmacological Class: Phenylacetic acid derivative / NSAID.
Product Specifications
| Feature | Details |
| Generic Name | Diclofenac Sodium Ophthalmic Solution |
| Strength | 0.1% (1 mg/mL) |
| Volume | 5 mL |
| Therapeutic Category | Anti-inflammatory / Ophthalmic Analgesic |
| Dosage Form | Sterile Eye Drops |
| Primary Indication | Post-operative Inflammation & Pain |
Mechanism of Action: How the Drop Works
The clinical efficacy of Profenac Eye Drop is derived from its ability to block the underlying triggers of ocular distress.
- Cyclooxygenase (COX) Inhibition: Diclofenac Sodium inhibits the enzymes COX-1 and COX-2, which are responsible for converting arachidonic acid into prostaglandins.
- Prostaglandin Suppression: By lowering prostaglandin levels in the eye tissues, the medication effectively reduces intraocular inflammation, vascular permeability, and pain signaling.
- Miosis Inhibition: During surgery, prostaglandins can cause the pupil to constrict; Profenac helps maintain pupillary dilation, assisting the surgeon during delicate procedures.
- Corneal Sensitivity Reduction: It provides a localized analgesic effect, making it highly useful for patients experiencing discomfort after refractive surgery (LASIK) or corneal abrasions.
Key Benefits of Profenac
- Rapid Pain Relief: Provides quick management of "gritty" sensations and sharp pain following eye surgery.
- Effective Swelling Control: Specifically targets the anterior chamber of the eye to reduce redness and fluid buildup.
- Cataract Surgery Recovery: A standard clinical choice for preventing cystoid macular edema (CME) and post-surgical inflammation.
- Steroid-Free Alternative: Offers powerful anti-inflammatory benefits for patients who cannot use corticosteroid eye drops due to concerns like increased intraocular pressure.
- Targeted Ocular Delivery: The 0.1% concentration is optimized for deep penetration into ocular tissues with minimal systemic absorption.
- Enhanced Surgical Outcomes: Supports a more stable surgical environment by controlling the eye's inflammatory response during and after the procedure.
Profenac Eye Drop Precautions
Important Safety Information
Profenac Eye Drop 0.1% (Diclofenac Sodium) is a nonsteroidal anti-inflammatory ophthalmic solution used for eye inflammation, post-surgery pain, and ocular swelling. Following precautions ensures safe and effective use while minimizing risks of eye irritation or systemic effects.
Medical Conditions to Consider
- Avoid use if you have allergy to diclofenac, other NSAIDs, or aspirin
- Patients with a history of eye infections, corneal ulcers, or recent ocular surgery should consult a doctor
- Use cautiously in patients with bleeding disorders or those on anticoagulants, as NSAIDs may increase bleeding risk
- Inform your doctor if you have asthma or other hypersensitivity reactions
Usage Related Precautions
- Do not touch the tip of the dropper to your eye or any surface to prevent contamination
- Follow the prescribed dosage; do not exceed the recommended frequency
- Avoid wearing contact lenses during treatment unless approved by your doctor, as it may worsen irritation
- Regular follow-up is recommended during prolonged use to monitor eye health and intraocular pressure
Special Population Warnings
| Category | Precaution |
|---|---|
| Pregnancy | Use only if clearly prescribed by an ophthalmologist |
| Breastfeeding | Consult your doctor; minimal systemic absorption, but caution advised |
| Children | Use only under medical supervision |
Lifestyle and Safety Advice
- Avoid rubbing or pressing on the treated eye
- Wash hands before and after applying drops to maintain hygiene
- Protect eyes from direct sunlight or dust to prevent irritation
- Store in a cool, dry place away from direct sunlight and out of reach of children
When to Seek Medical Help
- Severe eye pain, redness, or swelling
- Vision changes such as blurred vision or decreased vision
- Signs of allergic reaction including rash around eyes or facial swelling
- Persistent stinging or irritation after use
Following these precautions ensures safe and effective use of Profenac Eye Drop 0.1% (Diclofenac Sodium) for relieving ocular inflammation, post-surgical eye pain, and swelling while minimizing risks.
Profenac Eye Drop Usage
To ensure maximum safety and clinical efficacy, Profenac Eye Drop must be administered using a sterile technique. Because Diclofenac Sodium 0.1% is a potent medication, following the prescribed dosing frequency is essential for maintaining therapeutic levels in the ocular tissues without causing unnecessary irritation.
Application and Dosing Guidelines
Standard Post-Operative Dosage: Typically, one drop in the affected eye 4 times daily, starting 24 hours after surgery and continuing for up to two weeks.
Surgical Pre-Treatment: For miosis inhibition, your surgeon may direct you to apply one drop every 30 minutes for 2 hours prior to the procedure.
Method of Application: * Wash your hands thoroughly before use.
Tilt your head back, pull down the lower eyelid to create a small pocket, and squeeze one sterile drop into the eye.
Close the eye for 1 to 2 minutes and apply gentle pressure to the tear duct (corner of the eye) to prevent the medication from draining into the throat.
Strict Precaution: Do not allow the dropper tip to touch your eye, eyelashes, or any other surface to avoid contaminating the 5ml solution.
Usage Summary Table
| Parameter | Guideline |
| Route of Administration | Ophthalmic (Eye Only) |
| Standard Strength | 0.1% Diclofenac Sodium |
| Common Frequency | 4 times daily |
| Contact Lens Protocol | Remove lenses; wait 15 minutes to reinsert |
| Storage Requirements | Store below 25°C in a cool, dry place |
Special Usage Instructions
Wait Between Medications: If you are using other eye drops (such as antibiotics or lubricants), wait at least 5 to 10 minutes between applications to ensure Profenac is not washed out.
Discard After 28 Days: For safety and sterility, any remaining Diclofenac solution should be discarded four weeks after the bottle is first opened.
Missed Dose Protocol: If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed one. Do not double the dose.
Temporary Blurred Vision: It is normal for your vision to be slightly blurry immediately after application. Do not drive or operate machinery until your vision has completely cleared.
Profenac Eye Drop Uses
Profenac Eye Drop is a high-potency non-steroidal anti-inflammatory drug (NSAID) containing Diclofenac Sodium 0.1%. It is clinically indicated for the management of ocular inflammation and pain, specifically in patients undergoing surgical procedures or those with non-infectious inflammatory conditions. By targeting the anterior segment of the eye, Profenac provides rapid relief from post-operative distress and supports the structural integrity of the ocular tissues during recovery.
Primary Clinical Uses
Post-Operative Inflammation: The primary treatment for reducing redness and swelling following cataract surgery.
Pain Management: Effectively relieves the "gritty" sensation and sharp pain associated with corneal refractive surgery (LASIK) and accidental corneal abrasions.
Miosis Inhibition: Used before and during surgery to prevent the pupil from constricting, ensuring a clear field for the ophthalmic surgeon.
Cystoid Macular Edema (CME) Prevention: Often prescribed to reduce the risk of fluid buildup in the retina after intraocular procedures.
Non-Infectious Ocular Inflammation: Manages chronic inflammatory conditions of the anterior chamber that do not involve a bacterial or viral infection.
Profenac Eye Drop Side Effects
Common Side Effects
Profenac Eye Drop 0.1% (Diclofenac Sodium) is a topical NSAID for ocular use to manage eye inflammation, post-surgical pain, and swelling. While generally safe, some mild side effects may occur:
- Temporary stinging or burning sensation in the eye after application
- Mild redness or irritation
- Watery eyes or tearing
- Dry eyes or slight discomfort
- Blurred vision shortly after instillation
These effects are usually temporary and resolve as your eye adjusts to the Profenac eye drop.
Less Common Side Effects
- Sensitivity to light (photophobia)
- Itching or mild swelling around the eye
- Headache
- Eye discomfort when blinking
Serious Side Effects
| Side Effect | Description |
|---|---|
| Severe eye pain | Persistent or worsening pain may indicate a serious problem |
| Vision changes | Sudden decrease in vision or persistent blurred vision |
| Corneal complications | Rare cases of corneal thinning or ulceration with prolonged use |
| Allergic reaction | Rash, swelling around eyes, or difficulty breathing |
| Excessive redness or discharge | Could indicate infection or severe irritation |
When to Seek Medical Help
- Persistent or severe eye pain, swelling, or redness
- Sudden vision changes or blurred vision
- Signs of allergic reaction, including swelling around the eyes or difficulty breathing
- Ongoing stinging, burning, or discomfort that does not improve
Safety Advice
- Follow the prescribed dosage and frequency exactly
- Avoid touching the dropper tip to the eye or any surface to prevent contamination
- Do not use with contact lenses unless approved by your ophthalmologist
- Discontinue use and consult your doctor if serious side effects occur
Being aware of these side effects ensures safe and effective use of Profenac Eye Drop 0.1% (Diclofenac Sodium) for reducing ocular inflammation, post-surgical pain, and swelling while minimizing risks.
Profenac Eye Drop FAQs
Q: What is the primary use of Profenac Eye Drop?
A: It is a high-potency non-steroidal anti-inflammatory drug (NSAID) eye drop primarily used to treat pain and inflammation following cataract surgery and to prevent pupil constriction (miosis) during ophthalmic procedures.
Q: How often should I apply Profenac Eye Drop?
A: For post-operative inflammation, the standard dosage is typically one drop in the affected eye 4 times daily, starting 24 hours after surgery and continuing for up to two weeks. Always follow your surgeon's specific instructions.
Q: Can I use Profenac Eye Drop while wearing contact lenses?
A: No. You should not wear contact lenses while using Profenac 0.1%. The preservative in the solution, Benzalkonium Chloride, can be absorbed by soft lenses and cause eye irritation. Wait at least 15 minutes after application before reinserting lenses, or as advised by your doctor.
Q: Is Profenac a steroid eye drop?
A: No, Profenac is an NSAID (Diclofenac Sodium). Unlike steroid eye drops, it does not typically cause a rise in intraocular pressure, making it a preferred choice for managing inflammation in many clinical scenarios.
Q: What should I do if my vision becomes blurry after using the drops?
A: It is common to experience temporary blurred vision immediately after applying any eye drop. This usually clears within a few minutes. Avoid driving or operating machinery until your vision is completely clear.
Q: Can I use Profenac alongside other eye drops?
A: Yes, but you must space them out. If you are using multiple ophthalmic medications, wait at least 5 to 10 minutes between applying different drops to ensure each one is properly absorbed.
Q: Does Profenac Eye Drop sting upon application?
A: Some patients may feel a transient stinging or burning sensation for a few seconds after the drop is placed in the eye. This is a common side effect and usually subsides quickly as the eye adjusts to the solution.
Q: How should I store the 5ml bottle?
A: Store the bottle at room temperature (below 25°C) in a cool, dry place away from direct sunlight. Ensure the cap is tightly closed after every use to maintain the sterility of the Diclofenac solution.
Q: How long is the bottle good for after opening?
A: For safety and to prevent contamination, any remaining Profenac solution should be discarded 4 weeks (28 days) after the bottle is first opened, even if there is liquid left.
Q: Can Profenac be used for itchy eyes caused by allergies?
A: While Diclofenac reduces inflammation, it is specifically indicated for surgical and traumatic inflammation. For seasonal allergies, your doctor may recommend a dedicated antihistamine eye drop instead.
Profenac Eye Drop Interactions
Drug and Eye Care Interactions
Profenac Eye Drop 0.1% (Diclofenac Sodium) is a topical NSAID for ocular use. While systemic absorption is minimal, it may interact with other medications or eye treatments, affecting safety or efficacy. Proper monitoring ensures safe use for eye inflammation, post-surgery care, and pain relief.
Common Drug Interactions
- Other NSAIDs or systemic diclofenac
May increase the risk of ocular or systemic side effects, including irritation or bleeding - Anticoagulants and blood thinners
Minimal systemic absorption, but theoretically may increase bleeding risk - Corticosteroid eye drops
Combined use may increase risk of corneal thinning or delayed healing - Other ophthalmic medications
Apply drops at least 5–10 minutes apart to avoid dilution or reduced effectiveness
Interaction with Health Conditions
| Condition | Interaction Impact |
|---|---|
| Eye infections | May worsen untreated infections; use under supervision |
| Corneal disease | Risk of delayed healing or ulceration when combined with other topical meds |
| Bleeding disorders | Monitor for increased ocular bleeding risk, especially with systemic anticoagulants |
| Asthma or NSAID allergy | May trigger hypersensitivity reactions |
Lifestyle and Safety Interactions
- Avoid wearing contact lenses unless approved by your doctor
- Wash hands before and after application to prevent cross-contamination
- Avoid touching the dropper tip to the eye or any surface to prevent infection
- Follow the prescribed schedule to ensure maximum efficacy for inflammation and pain relief
Precautionary Advice
- Inform your doctor about all other eye drops, systemic medications, or supplements you are using
- Report symptoms like increased redness, pain, blurred vision, or unusual discharge
- Discontinue use and seek medical attention if severe irritation or allergic reaction occurs
Proper management of interactions ensures safe use of Profenac Eye Drop 0.1% (Diclofenac Sodium) for ocular inflammation, post-surgery pain, and swelling control while minimizing potential risks.
| Manufacturer | : | Cipla Pharma, India |
| Trade Name | : | Voltaren |
| Generic Search | : | Diclofenac Sodium |
| Strength | : | 0.1% (5 ml ) |
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