Permite Cream (Permethrin) | Elimite Alternative’s | Used to Treat Scabies, Head Lice, Mite, and Other Parasitic Infestations
Permite Cream (Permethrin) is a topical antiparasitic medication used for the treatment of scabies and head lice infestations. It is effective against scabies, which is a highly contagious and itchy skin infestation caused by the itch mite Sarcoptes scabiei. Additionally, it is used to treat infestations by head lice (head pediculosis) and pubic lice (pubic pediculosis). Elimite and Permite are the brand name for Permethrin.
Product Overview
Permite Cream contains Permethrin, a potent pediculicide and scabicide medication used for the topical treatment of infestations caused by scabies. It works by disrupting the sodium transport mechanisms in the nerve cell membranes of parasites, resulting in delayed repolarization and paralysis of the pest, which ultimately leads to their death. This cream is indicated for the eradication of scabies and is formulated to be applied directly to the skin, providing a targeted approach to eliminate the infestation. It is essential to use this medication exactly as directed to ensure the complete removal of the parasites and their eggs.
Product Composition
- Permethrin 5 percent w/w
- Cream base excipients
Product Specification
| Feature | Details |
| Brand Name | Permite |
| Category | Scabicide / Antiparasitic |
| Form | Topical Cream |
| Indication | Treatment of scabies |
| Storage Conditions | Store in a cool, dry place; keep tightly closed |
Mechanism of Action
- Acts on the nerve cell membranes of parasites to disrupt sodium channel currents
- Causes paralysis and subsequent death of the Sarcoptes scabiei mites
- Effectively targets both the adult mites and their ova (eggs)
- Provides a residual effect that helps prevent re-infestation shortly after application
Key Benefits
- Highly effective in the treatment of scabies infestations
- Easy-to-apply cream formulation ensures thorough coverage
- Generally safe and well-tolerated when used according to instructions
- Eliminates both mites and their eggs to break the cycle of infestation
Precautions
General Precautions
| Precaution | Details |
|---|---|
| External Use Only | Apply only on skin; do not ingest |
| Avoid Eyes and Mucosa | Keep away from eyes, mouth, nose, and genital mucous membranes |
| Full Body Application | Apply as directed, usually over the entire body from neck down (for scabies) |
| Proper Duration | Leave on for the prescribed time before washing off |
| Hand Hygiene | Wash hands before and after application |
Skin Safety Precautions
- Do not apply on broken, inflamed, or infected skin unless advised by a doctor
- Temporary itching may continue even after treatment due to healing response
- Avoid scratching treated areas to prevent secondary infection
- Discontinue use if severe irritation or allergic reaction occurs
Special Precautions
- Use cautiously in infants, children, and elderly patients
- Consult a doctor before use during pregnancy or breastfeeding
- Treat all close contacts simultaneously to prevent reinfection
- Not recommended for repeated unsupervised use
Hygiene Precautions
- Wash clothing, bedding, and towels in hot water after use
- Avoid sharing personal items like clothes, towels, or combs
- Maintain proper personal hygiene during treatment
Storage Precautions
- Store in a cool and dry place
- Protect from direct sunlight and heat
- Keep tube tightly closed after use
- Keep out of reach of children
Usage
Dosage
Apply a thin layer of the cream to the entire body from the neck down, including the spaces between the fingers and toes, under the fingernails, and in skin folds, or as specifically directed by your healthcare professional.
Administration
| Instruction | Method |
| Preparation | Ensure the skin is cool, clean, and dry before application |
| Application | Massage the cream thoroughly into all skin surfaces from the neck down |
| Technique | Leave the cream on the skin for the recommended duration—usually 8 to 14 hours—before washing it off |
| Consistency | Follow the application schedule strictly and wash all clothing and bedding used during the infestation |
Uses
Treatment of scabies (Sarcoptes scabiei infestation)
Management of associated intense itching caused by mite infestation
Side Effects
Common Side Effects
- Mild burning or stinging sensation after application
- Temporary itching or irritation
- Redness of the skin
- Tingling or numbness at application site
- Dry skin
Less Common Side Effects
- Rash or mild swelling
- Increased skin sensitivity
- Mild dizziness or headache (rare, usually due to absorption)
- Flaking or peeling of skin
- Discomfort or tightness of treated area
Serious Side Effects
| Serious Side Effect | Description |
|---|---|
| Severe allergic reaction | Rash, swelling, or difficulty breathing indicating hypersensitivity |
| Intense skin irritation | Severe redness, burning, or pain that does not improve |
| Worsening rash | Spread or aggravation of skin lesions instead of improvement |
| Blister formation | Fluid-filled blisters on treated skin (rare) |
| Neurological symptoms (rare) | Dizziness, confusion, or unusual sensations due to excessive exposure |
Monitoring
- Monitor skin for persistent redness, itching, or worsening irritation
- Watch for signs of allergic reaction after application
- Discontinue use if severe discomfort or rash occurs
- Consult a doctor if symptoms do not improve after recommended treatment duration
FAQs
Q: Should I apply this to my face?
A: Generally, the cream is applied from the neck down. Avoid contact with the eyes, mouth, and nose. If it gets in these areas, rinse thoroughly with water.
Q: How long should I leave the cream on?
A: You should leave the cream on the skin for the time specified by your doctor, typically between 8 and 14 hours, before washing it off with a bath or shower.
Q: Can I use this if I am pregnant?
A: Consult your doctor before using this medication if you are pregnant or breastfeeding to determine if it is appropriate for your situation.
Q: Do I need to treat everyone in my household?
A: Often, doctors recommend that all household members and close contacts be treated simultaneously to prevent the spread of the infestation, even if they do not have symptoms.
Q: Why does the itching continue after treatment?
A: It is common for itching to persist for a few weeks after the mites have been killed because the body continues to react to the presence of mite debris. Consult your doctor if the itching becomes severe or worsens.
Interactions
Drug Interactions
| Drug / Product Type | Interaction Details |
|---|---|
| Topical Corticosteroids | May reduce effectiveness of permethrin or mask symptoms if used together |
| Other Scabies Treatments | Combining multiple scabicidal agents may increase skin irritation without added benefit |
| Antibacterial Creams | No significant interaction, but unnecessary combination should be avoided unless prescribed |
| Topical Retinoids | May increase skin irritation and dryness if used on same area |
| Oral Antihistamines | Generally safe and often used to reduce itching during treatment |
Topical Product Interactions
- Avoid applying multiple medicated creams simultaneously unless directed by a doctor
- Do not mix with strong antiseptics or irritant skin treatments
- Layering products may reduce effectiveness or increase skin sensitivity
Skin Care Product Interactions
- Avoid alcohol-based lotions, harsh soaps, and fragranced products on affected skin
- Strong chemical-based skincare products may worsen irritation
- Use mild, non-irritating cleansers during treatment
Condition Based Interactions
- In eczema or sensitive skin conditions, use only under medical supervision
- Avoid use on severely inflamed or broken skin unless advised
- May interact with ongoing dermatological treatments affecting skin barrier
Hygiene Interaction Considerations
- Reinfection risk increases if infected clothing or bedding is not properly cleaned
- Close contact with untreated individuals may reduce treatment effectiveness
- Proper sanitation is essential for successful eradication of infestation
| Manufacturer | : | A. Menarini India Pvt Ltdine HCL) |
| Trade Name | : | Elimite |
| Generic Search | : | Permethrin |
| Strength | : | 5% (60gm) |
Latest Products
