Palbace Capsule (Palbociclib)

Introduction of Palbace Capsule (Palbociclib)

Ibrance (generic name: Palbociclib) is a prescription medication commonly used in the treatment of certain types of breast cancer. It belongs to a class of drugs known as CDK4/6 inhibitors, which work by blocking specific proteins involved in the growth and division of cancer cells.

There are several alternatives to Palbociclib Capsule that may be considered based on individual circumstances and the recommendation of a healthcare professional. Some common alternatives include other CDK4/6 inhibitors such as Ribociclib (Kisqali) and abemaciclib (Verzenio). Each medication has its own unique profile of effectiveness and side effects, so it is crucial to discuss the options with your doctor to determine the most suitable treatment approach for your specific condition.

Buy Palbociclib Capsule online at onlinegenericmedicine.com:
Onlinegenericmedicine.com is an online pharmacy that offers Palbociclib Capsule (brand name: Palbace) for purchase. When buying medications online, it is essential to ensure that the website is reputable, licensed, and adheres to safety standards. Always consult with a healthcare professional before purchasing prescription drugs online to ensure their authenticity and appropriateness for your condition.

Palbociclib is used for

Treating certain kinds of breast cancer in women past menopause. It may also be used for other conditions as determined by your doctor.

Palbociclib is a cyclin-dependent kinase (CDK) inhibitor. It works by stopping the growth of cancer cells.

Do NOT use palbociclib if:
you are allergic to any ingredient in palbociclib
you are taking bosentan, carbamazepine, efavirenz, etravirine, modafinil, nafcillin, phenytoin, rifampin, or St. John's wort
Contact your doctor or health care provider right away if any of these apply to you.

Before using palbociclib

Some medical conditions may interact with palbociclib. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have kidney problems, liver problems, or any symptoms of infection (eg, fever, chills, cough, sore throat)
Some MEDICINES MAY INTERACT with palbociclib. Tell your healthcare provider if you are taking any other medicines, especially any of the following:

Clarithromycin, indinavir, itraconazole, ketoconazole, lopinavir/ritonavir, nefazodone, nelfinavir, posaconazole, ritonavir, saquinavir, telaprevir, telithromycin, verapamil, or voriconazole because they may increase the risk of palbociclib's side effects
Bosentan, carbamazepine, efavirenz, etravirine, modafinil, nafcillin, phenytoin, rifampin, or St. John's wort because they may decrease palbociclib's effectiveness
Alfentanil, cyclosporine, dihydroergotamine, ergotamine, everolimus, fentanyl, midazolam, pimozide, quinidine, sirolimus, or tacrolimus because the risk of their side effects may be increased by palbociclib
This may not be a complete list of all interactions that may occur. Ask your healthcare provider if palbociclib may interact with other medicines that you take. Check with your healthcare provider before you start, stop, or change the dose of any medicine.

How to use palbociclib:

Use palbociclib as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Palbociclib. Talk to your pharmacist if you have questions about this information.
• Follow how to take palbociclib as you have been told by your doctor. Do not use more than you were told to use.
• Take palbociclib by mouth with food.
• Swallow palbociclib whole. Do not chew, crush, or open before swallowing.
• Do not take capsules that are broken, cracked, or that look damaged.
• Do not eat grapefruit or drink grapefruit juice while you use palbociclib.
• Take palbociclib at the same time of day.
• To gain the most benefit, do not miss doses.
• Take as you have been told, even if you feel well.
• If you vomit after taking palbociclib, do not repeat the dose.
• If you miss a dose of palbociclib, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
• Ask your healthcare provider any questions you may have about how to use Palbociclib.

Discounted Palbociclib Capsule:
Discounted Palbociclib Capsule may be available through various means, including patient assistance programs, manufacturer discounts, or insurance coverage. However, it is crucial to be cautious when encountering significantly discounted medications from unverified sources, as they may be counterfeit or of substandard quality. Consult with your healthcare provider or pharmacist to explore legitimate avenues for cost-saving options.

Important safety information of Palbociclib Capsule

Tell your doctor or dentist that you take Palbociclib before you receive any medical or dental care, emergency care, or surgery.
Palbociclib may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.
Palbociclib may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
Blood clots in the lungs have happened with palbociclib. Blood clots in the lungs may be serious or life-threatening. Call your doctor right away if you have chest pain or pressure, coughing up blood, fast breathing, fast heartbeat, or shortness of breath.
If you may become pregnant, you must use an effective form of birth control while you take Palbociclib and for at least 2 weeks after you stop taking it. If you have questions about effective birth control, talk with your doctor.
Lab tests may be performed while you use Palbociclib. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
PREGNANCY and BREAST-FEEDING: Palbociclib may cause harm to the fetus. If you think you may be pregnant, contact your doctor right away. It is not known if this medicine is found in breast milk. Do not breastfeed while taking palbociclib.
Possible side effects of palbociclib:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Decreased appetite; diarrhea; hair thinning or loss; mouth irritation or mouth sores; nausea; nose or throat irritation; tiredness; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); burning, numbness, or tingling; dizziness; symptoms of bleeding (eg, vomiting blood or vomit that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; nosebleeds; unusual vaginal bleeding; bruises without a reason or that get bigger; any bleeding that is severe or that you cannot stop); symptoms of infection (eg, fever, chills, sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, painful urination, mouth sores, a wound that will not heal, anal itching or pain); unusual tiredness or weakness.

If OVERDOSE is suspected:

Contact your local poison control center, or emergency room immediately.

Proper storage of palbociclib:

Store palbociclib at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep palbociclib out of the reach of children and away from pets.

Drug Interaction of Palbociclib Capsule

Palbociclib Capsule (brand name: Palbace) can interact with certain medications, potentially affecting their efficacy or increasing the risk of side effects. It is important to inform your healthcare provider about all the medications, supplements, and herbal products you are taking before starting Palbociclib treatment.

Palbociclib is primarily metabolized by the liver enzyme CYP3A4, so drugs that inhibit or induce this enzyme can impact the concentration of Palbociclib in the body. Strong CYP3A inhibitors, such as ketoconazole, itraconazole, and clarithromycin, can increase the levels of Palbociclib, leading to an increased risk of side effects. On the other hand, strong CYP3A inducers like rifampin, phenytoin, and carbamazepine can decrease the levels of Palbociclib, potentially reducing its effectiveness.

Additionally, certain medications may prolong the QT interval of the heart, which can increase the risk of a potentially serious heart rhythm abnormality. Palbociclib itself may also have a mild effect on the QT interval.

FAQs

Palbace Capsule (Palbociclib)

What is Palbociclib Capsule used for?

Palbociclib Capsule, also known by its brand name Ibrance, is primarily used in the treatment of hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) advanced or metastatic breast cancer.

How does Palbociclib Capsule work?

Palbociclib works by inhibiting specific proteins called cyclin-dependent kinases 4 and 6 (CDK4/6), which are involved in promoting cell division. By blocking these proteins, Palbociclib slows down the growth and division of cancer cells.

How should Palbociclib Capsule be taken?

Palbociclib Capsule is usually taken orally once daily for 21 consecutive days, followed by 7 days of treatment. It is important to follow the dosing instructions provided by your healthcare provider and to take the medication with food.