Palbace Capsule (Palbociclib) | Ibrance | Used to Treat Breast Cancer

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Palbace 125 mg (Palbociclib) is used for treating certain kinds of breast cancer in women past menopause. It may also be used for other conditions as determined by your doctor. Palbociclib is a cyclin-dependent kinase (CDK) inhibitor. It works by stopping the growth of cancer cells.  Ibrance is another brand name for Palbociclib.

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Palbace 125mg Capsule (Palbociclib 125mg)
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21 Capsule/s $3,166.70

Ibrance (generic name: Palbociclib) is a prescription medication commonly used in the treatment of certain types of breast cancer. It belongs to a class of drugs known as CDK4/6 inhibitors, which work by blocking specific proteins involved in the growth and division of cancer cells.

There are several alternatives to Palbociclib Capsule that may be considered based on individual circumstances and the recommendation of a healthcare professional. Some common alternatives include other CDK4/6 inhibitors such as Ribociclib (Kisqali) and abemaciclib (Verzenio). Each medication has its own unique profile of effectiveness and side effects, so it is crucial to discuss the options with your doctor to determine the most suitable treatment approach for your specific condition.

USA Brand NameIbrance
Strength75mg, 100mg, 125mg
Generic NamePalbociclib
ManufacturerPfizer Ltd, India
StorageStore Below 30° C

Useses Of Palbociclib

  • Treating certain kinds of breast cancer in women past menopause. It may also be used for other conditions as determined by your doctor.

  • Palbociclib is a cyclin-dependent kinase (CDK) inhibitor. It works by stopping the growth of cancer cells

Side Effects Of Palbociclib

  • Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); burning, numbness, or tingling; dizziness.

  • symptoms of bleeding (eg, vomiting blood or vomit that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; nosebleeds; unusual vaginal bleeding; bruises without a reason or that get bigger; any bleeding that is severe or that you cannot stop).

  • symptoms of infection (eg, fever, chills, sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, painful urination, mouth sores, a wound that will not heal, anal itching or pain); unusual tiredness or weakness

FAQS

  • What is Palbociclib Capsule used for?
    Palbociclib Capsule, also known by its brand name Ibrance, is primarily used in the treatment of hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) advanced or metastatic breast cancer.

  • How does Palbociclib Capsule work?
    Palbociclib works by inhibiting specific proteins called cyclin-dependent kinases 4 and 6 (CDK4/6), which are involved in promoting cell division. By blocking these proteins, Palbociclib slows down the growth and division of cancer cells.

  • How should Palbociclib Capsule be taken?
    Palbociclib Capsule is usually taken orally once daily for 21 consecutive days, followed by 7 days of treatment. It is important to follow the dosing instructions provided by your healthcare provider and to take the medication with food.

Interaction of Palbociclib Capsule

  • Palbociclib Capsule (brand name: Palbace) can interact with certain medications, potentially affecting their efficacy or increasing the risk of side effects. It is important to inform your healthcare provider about all the medications, supplements, and herbal products you are taking before starting Palbociclib treatment.

  • Palbociclib is primarily metabolized by the liver enzyme CYP3A4, so drugs that inhibit or induce this enzyme can impact the concentration of Palbociclib in the body. Strong CYP3A inhibitors, such as ketoconazole, itraconazole, and clarithromycin, can increase the levels of Palbociclib, leading to an increased risk of side effects. On the other hand, strong CYP3A inducers like rifampin, phenytoin, and carbamazepine can decrease the levels of Palbociclib, potentially reducing its effectiveness.

  • Additionally, certain medications may prolong the QT interval of the heart, which can increase the risk of a potentially serious heart rhythm abnormality. Palbociclib itself may also have a mild effect on the QT interval.
More Information
Manufacturer:Pfizer Ltd, India
Trade Name:Ibrance
Generic Search:Palbociclib
Strength:75mg, 100mg, 125mg
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