Lesuride Injection (Levosulpiride)

Introductions of Lesuride Injection

Lesuride Injection is a medication that contains Levosulpiride, which is a selective dopamine D2 receptor antagonist. It is primarily used to treat various gastrointestinal disorders such as gastroparesis, gastroesophageal reflux disease (GERD), and irritable bowel syndrome (IBS). It is also sold under the brand name NEOPRAD.

Levosulpiride works by blocking dopamine receptors in the brain and gut, which results in an increase in the release of acetylcholine, a neurotransmitter that regulates gastrointestinal motility. This leads to an improvement in the symptoms associated with gastrointestinal disorders, such as nausea, vomiting, bloating, and abdominal pain.

Lesuride Injection is available in a sterile form for intravenous or intramuscular injection. It is typically administered in a clinical setting by a healthcare professional. The dosage of Levosulpiride Injection may vary depending on the patient's age, medical condition, and other factors. Lesuride is available in Tablets, injections, and chewable tablets form with the same active ingredient Levosulpiride. All these various forms of Levosulpiride should be taken with a prescription by your healthcare doctor.

It is important to consult with a doctor or healthcare provider before taking Lesuride Injection or any medication, as they can provide guidance on dosage, potential side effects, and interactions with other medications or medical conditions.

What is the dosage of Lesuride Injection?

The recommended dosage for adults is 25-50mg of Levosulpiride Injection, given through intravenous or intramuscular injection, two to three times a day. The maximum daily dosage should not exceed 200mg per day.

 What are the other Uses of Neoprad?

  Neoprad Injection (Levosulpiride) can also be used for Gastroparesis, Gastroesophageal reflux disease (GERD), Irritable bowel syndrome (IBS), Dyspepsia.

There are some Common and Major Side Effects

Nausea
Headache
Dizziness
Sleepiness
Restlessness
Insomnia
Dry mouth
Diarrhea
Constipation
Abdominal pain
Increased levels of prolactin in the blood (which can lead to breast enlargement and milk production in both men and women)

Less common side effects of Lesuride injection include:

Extrapyramidal symptoms (movement disorders such as tremors, stiffness, and restlessness)
Akathisia (an uncomfortable feeling of restlessness and a need to move around)
Tardive dyskinesia (a disorder that causes uncontrollable movements of the face and body)
Allergic reactions such as rash, itching, and swelling

What are the benefits of Lesuride injection?

Neoprad can be very beneficial in all of these Gastrointestinal disorders, Nausea, and vomiting, Mental health conditions, Milk production, and Management of Parkinson's disease.

Some Precautions to be taken while using Neoprad

Medical history: Before taking Lesuride Injection Levosulpiride, it is important to inform your doctor if you have a history of medical conditions such as liver or kidney disease, epilepsy, Parkinson's disease, or any other neurological disorders.

Allergies: If you are allergic to levosulpiride or any other ingredients in Lesuride Injection, inform your doctor.

Pregnancy and breast-feeding: Lesuride Injection Levosulpiride may not be safe for use during pregnancy or while breastfeeding. Consult your doctor before taking this medication.

Children: The safety and effectiveness of Lesuride Injection Levosulpiride in children have not been established. Consult your doctor before giving this medication to a child.

Interactions: Lesuride Injection Levosulpiride may interact with other medications, including certain antidepressants, antipsychotics, and medications for Parkinson's disease. Inform your doctor of all medications you are taking before starting Lesuride Injection Levosulpiride.

Driving and operating machinery: Lesuride Injection Levosulpiride can cause dizziness and drowsiness, which may impair your ability to drive or operate machinery. Avoid driving or operating machinery until you know how the medication affects you.

Alcohol: It is not recommended to consume alcohol while taking Lesuride Injection Levosulpiride, as it may increase the risk of side effects.

 Some Commonly Asked Questions

Q: What is Lesuride Injection Levosulpiride used for?

A: Lesuride Injection Levosulpiride is a medication used to treat various conditions such as gastroesophageal reflux disease (GERD), irritable bowel syndrome (IBS), and certain psychiatric disorders.

Q: Can I drink alcohol while taking Lesuride Injection Levosulpiride?

A: It is not recommended to drink alcohol while taking Lesuride Injection Levosulpiride, as it can increase the risk of side effects and may also reduce the effectiveness of the medication.

Q: Lesuride Injection Levosulpiride can be taken by Pregnant women?

A: No, it will be harmful to growing a fetus, so Levosulpiride is not recommended by Pregnant women in case consult your doctor.

Q: Is Lesuride Injection Levosulpiride safe for everyone to take?

A: Lesuride Injection Levosulpiride may not be safe for everyone, particularly those with a history of certain medical conditions such as epilepsy or Parkinson's disease. It is important to talk to your doctor about your medical history before taking this medication.

Q: Can I drive or operate machinery while taking Lesuride Injection Levosulpiride?

A: Lesuride Injection Levosulpiride can cause dizziness and sleepiness, which may impair your ability to drive or operate machinery. It is important to avoid these activities until you know how the medication affects you.

Some Medications Interact with Levosulpiride

Levosulpiride may interact with other drugs or medications like 

Central nervous system depressants: This can cause excessive drowsiness, sedation, and respiratory depression.

Antipsychotic medications: This can increase the risk of movement disorders.

Serotoninergic medications: With these medications increase serotonin levels, such as selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs). 

Medications that prolong QT interval: If Levosulpiride interacts then it can increase the risk of abnormal heart rhythms.

 Dopamine antagonists: This medication is used to treat gastrointestinal disorders, if levosulpiride interacts with it then it may block the effect of Dopamine antagonists.