Indivan Capsule (Indinavir)

Indinavir Capsule for HIV

What is Indivan Capsule (Indinavir)?

Indinavir is an antiviral drug that prevents the human immunodeficiency virus or HIV from multiplying in your body. This medication is prescribed for the treatment of HIV which causes the acquired immunodeficiency syndrome or AIDS. Indinavir is sold under various trade names, a couple of which are Crixivan and Indinavir (made by Merck). This medicine may also be prescribed for treatments not mentioned here.Crixivan is another brand name for Indinavir.

How it works

Indinavir belongs to a class of medications called retroviral protease inhibitors. It works by blocking the activity of an enzyme protease which results in the formation of defective viruses and decreases the viral load in the body. Indinavir also lowers the risk of getting illness related to HIV and improves immunity.

Uses of Indivan Capsule (Indinavir)

Indinavir is used to treat HIV (human immunodeficiency virus) infection along with other medications.

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Important Information about Indivan Capsule (Indinavir)

• Indinavir (Crixivan, Indinavir) will not cure your body of HIV. You can still spread the virus to other people through infected blood (via infected needles, razors, or toothbrushes) or through unsafe sexual practices (ensure proper barrier contraception). You must take care of these things and employ proper measures so as not to spread the virus.
• You may get life-threatening side effects if you take Indinavir together with alfuzosin, amiodarone, lovastatin, midazolam, quinidine, pimozide, rifampin, sildenafil, simvastatin, St. John&rsquo's wort, triazolam, or an ergot medicine like dihydroergotamine, ergonovine, ergotamine, or methylergonovine.
• Indinavir is an FDA pregnancy category C drug. It is not known to harm an unborn baby if taken during pregnancy. However, HIV can be passed to the baby if the mother is not treated properly during pregnancy. Remember to take all medications for HIV as prescribed to prevent your baby from contracting the HIV virus.

Before taking Indivan Capsule (Indinavir)

• Before taking Indinavir antiviral medicine (Crixivan, Indinavir), take care of all precautions mentioned above. Discuss them with your doctor and clear all doubts that you may have about this drug.
• Also, to ensure that this medicine is safe for you, you must inform your doctor in advance if you have these conditions: any liver disease, kidney disease, diabetes, a bleeding disorder such as hemophilia, or high cholesterol or triglycerides.

How should I take Indinavir?

• Take Indinavir antiviral HIV medication (Crixivan, Indinavir) strictly according to your doctor’s direction or according to the instructions on the medication label. Do not alter the dosage unless your doctor advises you to do so. Also, do not take this medication after the prescribed period is over. All medications come with a patient leaflet. Refer to the instructions in them for detailed information on that particular medication.
• Take Indinavir on an empty stomach at least 1 hour before or 2 hours after a meal, or as directed by your doctor. HIV is usually treated with a combination of drugs. Always take the prescribed drugs as directed by your doctor. Store this medication in a cool and dry place.

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What if I miss a dose?

If you miss a dose of Indinavir, take it as soon as you remember. Don’t take the missed dose if the time to take the next dose is almost up. Taking multiple doses near each other can lead to excess medication in your body which can be harmful.

What if I overdose?

In case of an overdose of Indinavir, get emergency medical attention or call the Doctor immediately.

Things and Activities to Avoid while Taking Indinavir

Indinavir will not help your body get rid of HIV. It will only stop the growth and multiplication of the virus. Chances of spreading HIV will still remain the same through unprotected sex, infected razors, needles, or toothbrush. Hence, avoid these activities and things.

Indivan Capsule (Indinavir) Side Effects

Stomach pain, nausea, vomiting, heartburn, loss of appetite, or headache are common side effects of Indinavir. If any of these conditions persist or deteriorate, get medical attention right away. This medicine may infrequently increase your blood sugar level which can cause or worsen diabetes. Let your doctor know right away if you develop symptoms of high blood sugar like increased thirst and urination. If you already have high blood sugar, monitor your blood sugar regularly while taking Indinavir.
Changes in body fat may also be seen while taking Indinavir, especially increased fat in the upper back and stomach areas while decreased fat in arms and legs.
Some people may experience deterioration of a previous medical condition as their immune system recovers, or develop new conditions due to an overactive immune system. Let your doctor know right away if you develop any new condition or if any of your existing conditions worsen.
The side effects mentioned above are not the only ones that you may experience or witness due to Indinavir. If you get any serious side effects due to this medication, contact your doctor right away.

Indinavir Dosing Information

Indinavir dosage may depend on a range of factors like age, sex, drug allergies, or seriousness of the condition among several other factors. Your dosage will be determined by your doctor after examining you properly. Remember to follow your doctor’s advice properly for best results.

Indivan Capsule (Indinavir) Interaction with other drugs

Some drugs can interact with Indinavir such as other HIV/AIDS medicines atorvastatin, bosentan, colchicines, fluticasone, itraconazole, methadone, omeprazole, phenytoin, rifabutin, salmeterol, warfarin, antidepressants, heart or blood pressure medicines, insulin or diabetes medicines, drugs for erectile dysfunction, or seizure medicines. There may be other medicines as well that can interact with Indinavir. Inform your doctor about all other medicines which you may be using. Never start a new medication without consulting your doctor first.

Expert advice

• Tell your doctor if you suffer from liver or kidney problems, allergies, diabetes, high cholesterol, hemophilia (a hereditary disorder that impairs the body’s ability to blood clotting), severe pain tenderness or weakness in the muscle, signs of infection, autoimmune disorder (immune system attacking healthy body tissues), bone problems after taking indinavir capsule or tablet.
• Indinavir is not recommended for children below 18 years of age.
• Do not drive or operate heavy machinery as indinavir may cause dizziness.
• Tell your doctor if you are planning to become pregnant or are breastfeeding.

Frequently asked questions

Indinavir

Q. Is indinavir safe during pregnancy?

Indinavir should only be used during pregnancy if the potential benefits justify the potential risk to the baby and no other alternative is available. Please follow your doctor's advice regarding its use.

Q. Is indinavir safe during breastfeeding?

Breastfeeding is not recommended in women suffering from HIV but indinavir can be used if there is no alternative for breast milk. Please follow your doctor's advice regarding breastfeeding.