Uses
Gentamicin is used to treat certain severe and serious bacterial infections. It is effective in respiratory tract infections, blood infections, kidney or bladder infections (urinary tract infections), eye infections, ear infections, burn and wound infections, infections in new born babies, gynaecological infections, puss filled swelling (abscess), and inflammation of the inner layer of the heart (endocarditis) due to bacteria.
How it works
Gentamicin belongs to group of medicines called aminoglycosides. It works by interrupting bacterial protein synthesis and inhibits the bacterial growth.
Common side effects
swelling of tissue under the skin, inflammation of mouth and lips, fainting, coughing, raised, nausea, fall in blood pressure, kidney problems, blood disorder, abnormal liver function, breathlessness, mental depression, abnormal blood counts, vomiting, noisy respiration, or abdominal cramps ; pale red, confusion, muscle weakness or paralysis of muscles, Damage to ear, abnormal brain function, diarrhea., reddish-purple discolouration of skin, sleepiness, widespread, fits, seeing or hearing things that are not really there, anemia, sneezing, potentially severe and life-threatening allergic reaction consisting of one or more of the following: rapid heart rate, balance disorder, sudden, itchy skin rash
Expert advice
It is given as a drip (intravenous infusion), as an injection directly into a vein or into a muscle; or as an ear or eye drops. Do not drive immediately after using gentamicin eyedrops because gentamicin in the eye may cause temporary blurring of vision. Gentamicin should be used with caution in premature babies because of their kidney immaturity, and in elderly people. Gentamicin may cause damage to the kidneys and/or nerves. Consult your doctor for monitoring Kidney function and drug levels in the blood during treatment. Consult your doctor, if you experience hearing loss, dizziness, numbness, skin tingling, muscle twitching, or seizures which may be signs of nerve damage. Do not start or continue the gentamicin and consult your doctor:
- If you have inflammation of the middle ear (otitis media), kidney or liver problem, open wound or damaged skin.
- If you are pregnant or planning to become pregnant or breastfeeding.
- If you experience itching, skin rashes, swelling of face, lips, throat or difficulty in breathing.
Frequently asked questions
Gentamicin
Q. Is gentamicin a macrolide, st***dor a sulfa drug?
Gentamicin does not contain sulfa and is not a macrolide, or st***dal drug. It is a broad spectrum aminoglycoside.
Q. Is gentamicin nephrotoxic?
Yes, gentamicin is a nephrotoxic drug. Please consult your doctor before taking the drug.
Q. Is gentamicin safe during pregnancy?
Gentamicin should only be given during pregnancy when need has been clearly established. Please consult your doctor before taking the drug.
Q. Is gentamicin safe for babies?
Gentamicin is safe for babies if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Does gentamicin cause hearing loss or burn?
Yes gentamicin can cause hearing loss if used inappropriately. It can cause burning of eyes.
Q. Is gentamicin used for pink eye?
Yes, gentamicin is used in the treatment of pink eye (conjunctivitis). Please consult your doctor before use.
Q. Does gentamicin dialyze out?
Yes, gentamicin is a dialyzable drug.
Q. What organisms does gentamicin cover? Does it cover anaerobes?
Gentamicin is mainly effective against pseudomonas, escherichia, enterobacter, klebsiella, staphylococcus, salmonella, serratia, and shigella species but rarely effective against streptococci and methicillin-resistant Staphylococcus aureus (mrsa). It does not act against anaerobes.