Estogel (Estradiol)

Introduction of Estogel (Estradiol)

Estogel contains a semi-synthetic female hormone, used as hormone replacement therapy to treat hypoestrogenism (estrogen deficiency), osteoporosis (osteoporosis), and symptoms associated with menopause (itching, vaginal dryness, hot flashes). In addition, it also helps prevent osteoporosis, making the skin less brittle in postmenopausal women. Estogel contains estradiol, a man-made (semi-synthetic) female sex hormone that regulates the menstrual cycle and ovulation. Estogel is given when the body does not produce enough natural estrogen. Estogel works by replacing the normal functions of estrogen in the body and treating symptoms associated with menopause. As menopause can last for several years, this treatment can dramatically improve your mood and daily life. Take Estogel as prescribed by your doctor. How long you should take Estogel for how long your doctor has prescribed depends on your condition. You may experience headaches, bloating, hair loss, nausea, breast pain, weight gain, and unusual vaginal bleeding in some cases. Most of these Estogel side effects do not require medical attention and gradually disappear over time. However, if side effects persist, contact your doctor. Before you start taking Estogel, please tell your doctor if you are already taking any other medicines such as hormone replacement therapy. If you have a history of vaginal bleeding, breast cancer, blood clots in your legs or lungs, please inform your doctor as the dose may need to be adjusted. Also, if you are pregnant or nursing, please do not take Estogel. Using Estogel may increase your risk of blood clots. While taking Estogel, you should regularly consult your doctor to properly monitor the effects of the drug. Fruit juices or products containing grapefruit should not be taken as they are known to interact with Estogel. Do not drink grapefruit juice and St. John's wort (a natural remedy for depression) with Estogel.

Uses of Estogel (Estradiol)

Hormone replacement therapy, Hypoestrogenism (estrogen deficiency), Osteoporosis (osteoporosis), and Menopause related symptoms (itching, vaginal dryness, hot flashes)

Directions for Use

Estogel may be keen on or without food. The tablet form of Estogel should be swallowed whole with a glass of water, without chewing or crushing it. Topical gels/creams should be applied as prescribed by your doctor. Wash your hands before applying the gel. Injections should only be used by professionals and should never be used on their own.

Side Effects of Estogel (Estradiol)

Like all medicines, Estogel also has side effects. In some cases, you may experience headaches, bloating, hair loss, nausea, weight gain, breast pain, and unusual vaginal bleeding. Most of these Estogel side effects do not require medical attention and gradually disappear over time. However, if side effects persist, contact your doctor.

Precautions of Estogel (Estradiol)

Do not take Estogel if you are allergic to Estogel or any of its ingredients. Estogel is known to be contraindicated if you have breast cancer, vaginal bleeding, blood clots in the legs (deep vein thrombosis), lungs (pulmonary embolism), veins (thrombosis), endometrial cancer uterus (endometrium), any blood clotting disorder in the heart. , recently had a heart attack, liver or kidney disease, porphyria (a group of liver diseases), high blood pressure. Also, if you are pregnant or breastfeeding, you should not use hormone replacement therapy. Avoid smoking as it greatly increases the risk of blood clots, stroke and heart attack when taking Estogel. Fruit juices or products containing grapefruit should not be taken as they are known to interact with Estogel.

Interactions of Estogel (Estradiol)

Drug-Disease Interactions: Estogel is known to be contraindicated if you have breast cancer, vaginal bleeding, blood clots in the legs (deep vein thrombosis), lungs (pulmonary embolism), venous thrombosis blood vessels (thrombosis), endometrial cancer (the lining of the uterus), any blood clotting disorder, recent heart attack, liver or kidney disease, porphyria (a group of liver diseases), High Blood Pressure.

Drug involvement: Estogel is known to interact with antiepileptic drugs (carbamezapine, phenytoin), drugs for infections (griseofulvin, rifampicin), medicines for viral infections (efavirenz, ritonavir, nelfinavir), high blood pressure (bosentan), anticoagulants (aspirin).

Food-Drug Interactions: Estogel is known to interact with grapefruit juice, St. John's Wort (natural remedy for depression). Also, do not smoke and drink alcohol while taking Estogel.

FAQ’s:-

How does Estogel work?

Estogel is used when the body does not produce enough natural estrogen. Estogel is used as hormone replacement therapy. It works by replacing the normal functions of estrogen in the body and treating symptoms associated with menopause.

When should Estogel not be used?

Do not use Estogel if you are allergic to peanuts, have unusual vaginal bleeding, have or have had any type of cancer (breast or uterine cancer), or are being treated with any other treatment any other treatment with estrogen. Tell your doctor before using Estogel if you have had a heart attack, stroke, blood clot, liver problems, are pregnant, nursing, plan to become pregnant or have any allergies to Estogels.

I have surgery, can I take Estogel?

No, Estogel should not be used if you are having surgery. You should tell your doctor, they may ask you to stop hormone replacement therapy about to 6 weeks before surgery to reduce the risk of blood clots forming.

Can Estogel Make You Gain Weight?

Estogel may cause weight gain or weight loss. This is a common side effect of Estogel. So if you exercise regularly and eat a healthy diet, you can prevent weight gain.

Who should not take Estogel?

Estogel must not be given to patients with abnormal vaginal bleeding, liver or kidney problems, or any bleeding disorder, breast or uterine cancer, who have had a stroke or seizure heart. It should also be avoided if you are pregnant or breastfeeding.