Cardicap TR Capsule (Isosorbide Dinitrate)

Introductions

Cardicap Capsule TR is a medication that contains the active ingredient isosorbide dinitrate. It belongs to a group of drugs called nitrates, which are used to treat heart conditions such as angina (chest pain). It is also sold under the brand name Isordil.

Cardicap Capsule TR works by relaxing the blood vessels in the body, which helps to increase blood flow and reduce the workload on the heart. This can help to relieve symptoms of angina, such as chest pain, and improve exercise tolerance. The "TR" in Cardicap Capsule TR stands for "timed release", which means that the medication is released slowly over time, rather than all at once. This can help to provide a more consistent and longer-lasting effect. Available strengths of Cardicap Capsule TR are 20mg and 40mg.

It is important to take Cardicap Capsule TR exactly as directed by your healthcare provider. Do not change your dose or stop taking the medication without first consulting with your doctor.

How does Cardicap Capsule TR work?

Isosorbide dinitrate works by relaxing the smooth muscles in the blood vessels, particularly those in the veins. This leads to the dilation of blood vessels, allowing more blood to flow through them. This increased blood flow helps to decrease the workload on the heart and reduces the amount of oxygen needed by the heart muscle.
Isosorbide dinitrate is a type of nitrate, which gets converted into nitric oxide (NO) in the body. Nitric oxide is a potent vasodilator, which means it relaxes the smooth muscles in the blood vessels, allowing them to widen and increase blood flow.

Isosorbide dinitrate also dilates the coronary arteries, which are the blood vessels that supply oxygen-rich blood to the heart muscle. By dilating these blood vessels, isosorbide dinitrate increases the blood flow to the heart muscle, which can help relieve chest pain associated with angina.
Overall, the vasodilatory effect of isosorbide dinitrate helps to improve blood flow throughout the body, reduce the workload on the heart, and relieve symptoms of angina.

Dosage

The usual starting dose of Cardicap Capsule TR is 40 mg taken orally once a day. The medication is typically taken in the morning and can be taken with or without food.
Your healthcare provider may adjust the dosage based on your individual needs and response to treatment. The maximum recommended daily dose of Cardicap Capsule TR is 80 mg.

Uses

Cardicap Capsule TR (isosorbide dinitrate) is used to treat certain heart conditions, including angina pectoris (chest pain) caused by coronary artery disease.

Cardicap Capsule TR is also used in the management of congestive heart failure, pulmonary hypertension, and some types of chronic heart failure.

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Side effects

• Headache
• Dizziness
• Flushing
• Low blood pressure
• Rapid heartbeat
• Nausea or vomiting
• Dry mouth
• Fatigue or weakness
• Fainting

These side effects are usually mild and may go away on their own as your body adjusts to the medication. However, if these symptoms persist or become severe, it is important to contact your healthcare provider.

In rare cases, Cardicap Capsule TR can cause more serious side effects, including:

• Severe hypotension (low blood pressure)
• Syncope (fainting)
• Methemoglobinemia (a blood disorder)
• Severe allergic reaction (anaphylaxis)

If you experience any of these more serious side effects, seek medical attention immediately.

How to overcome these side effects

1. Headache: You can try taking over-the-counter pain relievers, such as acetaminophen or ibuprofen, to help relieve headaches. It may also be helpful to rest in a quiet, dark room until the headache subsides.

2. Dizziness or lightheadedness: To reduce the risk of dizziness or lightheadedness, try getting up slowly from a sitting or lying position. If you feel dizzy or lightheaded, sit or lie down until the feeling passes.

3. Flushing: Flushing, or redness and warmth of the skin, may occur while taking Cardicap Capsule TR. This is usually mild and will go away on its own. Drinking cool water or using a cool compress may help relieve the sensation.

4. Low blood pressure: Cardicap Capsule TR can cause a drop in blood pressure, which may cause dizziness or lightheadedness. It is important to stay hydrated and to avoid standing up too quickly to reduce the risk of low blood pressure.

5. Nausea or vomiting: If you experience nausea or vomiting while taking Cardicap Capsule TR, try eating small, frequent meals throughout the day and avoiding spicy or greasy foods. If the symptoms persist, contact your healthcare provider.

Benefits

1. Relief of angina symptoms: Cardicap Capsule TR is commonly used to treat angina, a condition in which the heart does not receive enough oxygen and nutrients due to narrowed or blocked blood vessels. By dilating blood vessels and improving blood flow, Cardicap Capsule TR can help relieve chest pain and other symptoms of angina.

2. Improved exercise tolerance: Cardicap Capsule TR can help improve exercise tolerance in individuals with angina, allowing them to participate in physical activity with less discomfort.

3. Management of heart failure: Cardicap Capsule TR may also be used in the management of heart failure, a condition in which the heart is unable to pump enough blood to meet the body's needs. By dilating blood vessels and reducing the workload on the heart, Cardicap Capsule TR can help improve the overall functioning of the heart.

4. Treatment of pulmonary hypertension: Cardicap Capsule TR may also be used in the treatment of pulmonary hypertension, a condition in which the blood pressure in the arteries of the lungs is abnormally high. By dilating blood vessels and reducing the workload on the heart, Cardicap Capsule TR can help improve blood flow and reduce symptoms of pulmonary hypertension.

Precautions and warnings

1. Allergies: If you have a known allergy to isosorbide dinitrate or any of its ingredients, do not take Cardicap Capsule TR.

2. Low blood pressure: Cardicap Capsule TR can cause a drop in blood pressure, which may lead to dizziness, lightheadedness, or fainting. If you have low blood pressure or are taking medications that lower blood pressure, talk to your healthcare provider before taking Cardicap Capsule TR.

3. Glaucoma: Cardicap Capsule TR can increase the pressure in the eyes, which may worsen the symptoms of glaucoma. If you have glaucoma or other eye problems, talk to your healthcare provider before taking Cardicap Capsule TR.

4. Liver or kidney disease: If you have liver or kidney disease, your body may not be able to process Cardicap Capsule TR effectively. Your healthcare provider may need to adjust your dosage or monitor you more closely while taking the medication.

5. Pregnancy and breast-feeding: It is not known whether Cardicap Capsule TR is safe for use during pregnancy or while breastfeeding. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your healthcare provider before taking Cardicap Capsule TR.

6. Drug interactions: Cardicap Capsule TR may interact with other medications, including blood pressure medications, erectile dysfunction medications, and certain antibiotics. Talk to your healthcare provider about all medications you are taking before starting Cardicap Capsule TR.

FAQ

Q: What is Cardicap Capsule TR used for?

A: Cardicap Capsule TR is used to treat angina, heart failure, and pulmonary hypertension. It works by dilating blood vessels and improving blood flow to the heart and lungs.

Q: How should I take Cardicap Capsule TR?

A: Cardicap Capsule TR should be taken exactly as prescribed by your healthcare provider. It is typically taken once or twice a day, with or without food. Swallow the capsule whole with a glass of water, and do not crush, chew, or break the capsule.

Q: Who should not take isosorbide dinitrate orally?

A: People who are allergic to isosorbide dinitrate or any of its ingredients should not take this medication. It is also not recommended for people who have severe anemia, closed-angle glaucoma, or low blood pressure. Additionally, isosorbide dinitrate should not be taken together with drugs called PDE-5 inhibitors, such as sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra), as this combination can cause a dangerous drop in blood pressure.

Q: What should I do if I miss a dose of Cardicap Capsule TR?

A: If you miss a dose of Cardicap Capsule TR, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed dose.

Q: What are the side effects of Cardicap Capsule TR?

A: Common side effects of Cardicap Capsule TR include headaches, dizziness, flushing, and nausea. More serious side effects may include low blood pressure, fainting, or a rapid heartbeat. If you experience any of these side effects, contact your healthcare provider immediately

Q: Can I drink alcohol while taking Cardicap Capsule TR?

A: It is not recommended to drink alcohol while taking Cardicap Capsule TR. Alcohol can increase the risk of side effects, such as dizziness and low blood pressure.

Q: Is it safe to take Cardicap Capsule TR during pregnancy or while breastfeeding?

A: It is not known whether Cardicap Capsule TR is safe for use during pregnancy or while breastfeeding. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your healthcare provider before taking Cardicap Capsule TR.

Q: Can I stop taking Cardicap Capsule TR abruptly?

A: No, you should not stop taking Cardicap Capsule TR abruptly without consulting with your healthcare provider. Suddenly stopping the medication can lead to a worsening of symptoms. Your healthcare provider may need to gradually reduce your dosage before discontinuing the medication.

Drug-drug and drugs-food Interactions

Drug-Drug Interactions: Cardicap Capsule TR (isosorbide dinitrate) may interact with other medications, including:

1. Blood pressure medications: Taking Cardicap Capsule TR with other blood pressure medications can cause a dangerous drop in blood pressure.

2. Erectile dysfunction medications: Taking Cardicap Capsule TR with medications for erectile dysfunction, such as sildenafil or tadalafil, can cause a dangerous drop in blood pressure.

3. Aspirin: Taking aspirin with Cardicap Capsule TR can increase the risk of side effects, such as headaches and dizziness.

4. Certain antibiotics: Some antibiotics, such as erythromycin and clarithromycin, can increase the levels of Cardicap Capsule TR in the body, leading to an increased risk of side effects.

Drug-Food Interactions: There are no known food interactions with Cardicap Capsule TR. However, drinking alcohol while taking Cardicap Capsule TR can increase the risk of side effects, such as dizziness and low blood pressure. It is recommended to avoid alcohol while taking Cardicap Capsule TR.