Sebifin Cream (Terbinafine)

Terbinafine HCl: An Antifungal Medicine

Terbinafine HCl is an antifungal medicine used to treat various fungal infections affecting fingernails, toenails, and skin. It works by inhibiting a key enzyme responsible for the formation of ergosterol, a vital component of the outer protective layer of fungi, thereby inhibiting fungal growth. Terbinafine HCl is available under different trade names, including Lamisil and Sebifin.

Terbinafine Cream Uses

Terbinafine is primarily used to treat fungal infections that affect the fingernails, toenails, and skin. These infections are commonly caused by dermatophytes, a group of fungi that can invade and thrive in keratinized tissues, such as nails and skin. Terbinafine's antifungal properties make it effective in treating these infections.

How Terbinafine HCl Works

Terbinafine HCl is an antifungal drug that belongs to the allylamine class. It exerts its antifungal effect by inhibiting squalene epoxidase, an essential enzyme in the biosynthesis of ergosterol, a critical component of the fungal cell membrane. The inhibition of this enzyme disrupts the synthesis of ergosterol, leading to the accumulation of squalene, which is toxic to fungi. Consequently, this disrupts the fungal cell membrane, impairs its integrity, and ultimately leads to the death of the fungal organism.

What is Terbinafine HCl?

Terbinafine HCl, or Terbinafine hydrochloride, is an active pharmaceutical ingredient in antifungal medications like Lamisil and Sebifin. These medications are available in various formulations, including oral tablets, oral granules, and topical creams. Terbinafine HCl's primary function is to combat fungal infections affecting nails and skin. While its efficacy has been established in the treatment of specific fungal infections, its use for other conditions should be discussed with a healthcare professional.

Important Information about Terbinafine HCl

Before initiating treatment with Terbinafine HCl, it is crucial to inform your doctor if you have a history of liver or kidney disease or an autoimmune disorder such as lupus or psoriasis. Completing the entire prescribed course of Terbinafine HCl is essential, even if the symptoms have improved or disappeared. Prematurely stopping the medication may result in incomplete eradication of the infection, leading to drug-resistant strains of fungi.

Some individuals taking Terbinafine HCl have experienced liver damage, leading to liver transplant or, in extreme cases, death. However, it is not entirely established that Terbinafine HCl is solely responsible for these instances, as underlying liver conditions might contribute. Seek immediate medical attention if symptoms of liver damage, such as nausea, upper stomach pain, itching, appetite loss, dark urine, clay-colored stools, or jaundice, occur.

Terbinafine HCl dosage information

The dosage of Terbinafine HCl may vary based on factors such as age, sex, drug allergies, and the severity of the infection. It is essential to follow the doctor's instructions carefully for optimal results. Terbinafine HCl is available in different forms, and the dosing may differ for each. It is crucial to adhere to the prescribed dosing schedule and not alter the dosage unless specifically advised by the doctor.

Terbinafine Cream brand names:

Terbinafine Cream is available under various brand names, with Lamisil and Sebifin being two common examples. These brand-name versions offer the same therapeutic benefits but may differ in price and packaging.

How to Take or Use Terbinafine HCl

For oral tablets and granules, Terbinafine HCl should be taken exactly as directed by the doctor or as per the instructions on the medication label. It is important not to take the medication beyond the prescribed period.

For topical cream application, wash hands thoroughly before and after use, unless applying it for a fingernail infection. Clean and dry the affected area before applying a small amount of the cream as directed. Avoid covering the treated area with occlusive dressings. Store Terbinafine HCl medication in a cool and dry place.

What if I Miss a Dose or Overdose?

If you miss a dose of Terbinafine HCl, take it as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule. Avoid taking multiple doses close together, as it may lead to an overdose. In case of an overdose, seek immediate medical attention or contact a healthcare professional.

Things and Activities to Avoid

While using Terbinafine HCl topical cream, avoid covering the treated skin areas, and refrain from applying any other creams on the treated area.

Terbinafine HCl Side Effects

Common side effects of Terbinafine HCl oral medicine may include diarrhea, stomach upset, or a temporary change or loss of taste. For the topical cream, common side effects may include burning, redness, itching, or irritation at the application site. If any of these side effects persist or worsen, seek medical assistance promptly. While serious side effects are rare, it is essential to seek immediate medical attention if any severe adverse reactions occur.

Precautions For Terbinafine Cream

Liver function tests are advisable during treatment with Terbinafine HCl, especially for people with liver diseases. Before taking Terbinafine HCl, inform your doctor if you have or had any of the following conditions: Psoriasis, Lupus erythematosus, Liver disease, Kidney problems, Depression, Alcohol abuse or dependence, Blood-related problems (e.g., anemia).

Terbinafine Cream online:

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Terbinafine Cream over the counter:

Terbinafine Cream is available over the counter in many pharmacies and drugstores. You can purchase it without a prescription, making it easily accessible for treating certain fungal infections.

Generic Terbinafine Cream:

Looking for an affordable alternative to branded Terbinafine Cream? Try our Generic Terbinafine Cream, which contains the same active ingredient and provides effective relief from fungal infections at a fraction of the cost.

Expert Advice

Liver function tests are advisable during treatment with terbinafine, especially for individuals with pre-existing liver diseases. Before starting terbinafine, consult your doctor if you have a history of:

• Psoriasis is a skin disease characterized by thick, scaly, itchy, dry, red, and sometimes painful patches on the skin.
• Lupus erythematosus, is an autoimmune disease that causes inflammation, affecting joints, skin, and other major organs.
• Liver disease, Kidney problems, or any conditions that may impact kidney function.
• Depression or a history of depression.
• Alcohol abuse or dependence.
• Blood-related problems, including low hemoglobin or red blood cells (anemia).

Consult your doctor if you experience any of the following symptoms during terbinafine treatment:

• Persistent urge to vomit (nausea).
• Loss of appetite.
• Unusual tiredness.
• Vomiting.
• Stomach pain.
• Yellowing of the skin and eyes (jaundice).
• Dark-colored urine or pale stools.
• Seek medical attention if you feel depressed or experience signs of depression during terbinafine treatment.
  
  

Contact your doctor immediately if you experience any signs of serious skin reactions, such as blisters, peeling of the skin, swelling of the face, lips, or tongue, or difficulty in swallowing or breathing. Notify your healthcare provider if you experience taste disturbances, including loss of taste, or smell disturbances, including loss of smell. Terbinafine creams and ointments are meant for external use only. Avoid using them on the face, and avoid contact with the eyes. In case of accidental eye contact, rinse thoroughly with running water. Before applying terbinafine cream, cleanse and dry the affected areas thoroughly and wash your hands. To achieve better treatment results, keep the affected areas clean by regularly washing and carefully drying them with clean towels and clothes. Avoid rubbing or scratching the skin.

Drug Interaction with Terbinafine Cream

When using terbinafine cream, it is essential to be aware of potential drug interactions to ensure safe and effective treatment. Although terbinafine cream is applied topically and has minimal systemic absorption, some medications may still interact with it. Inform your healthcare provider about all medications, including over-the-counter drugs, herbal supplements, and vitamins, that you are currently using to avoid potential complications.

There are no known serious drug interactions reported with terbinafine cream. However, it is always best to consult with your doctor before combining it with other topical medications to avoid any adverse effects or potential interactions. Additionally, if you experience any unexpected skin reactions or changes during the course of terbinafine cream treatment, promptly inform your healthcare provider for appropriate evaluation and management. Remember that your doctor is the best source of guidance regarding drug interactions and can tailor your treatment plan accordingly to ensure optimal therapeutic outcomes.

Frequently Asked Questions about Terbinafine

Is terbinafine safe during lactation?

Terbinafine is not recommended during lactation, as it passes into breast milk when taken orally.

Is terbinafine/bricanyl a steroid/sulfa drug?

Terbinafine is an antifungal drug and does not have chemical structures or effects similar to steroids or sulfa drugs.

Is terbinafine effective/FDA approved/contraindicated with asthma?

Terbinafine is effective in treating fungal infections affecting nails, toenails, and skin when used as advised by a doctor. It is FDA-approved and not contraindicated in asthma.

Is terbinafine safe or dangerous?

Terbinafine is safe if used as prescribed by a doctor and for the recommended duration.

Is terbinafine used to treat ringworm?

Terbinafine can be used to treat fungal infections caused by ringworm (tinea corporis, tinea cruris, and tinea pedis) if considered appropriate based on the severity and site of infection.

What is Sebifin/Bricanyl/Athakind used for?

Sebifin/Bricanyl/Athakind are trade names for the active drug terbinafine, used to treat fungal infections affecting nails, toenails, and skin.

Can I take terbinafine/Lamisil with ibuprofen, amoxicillin, prednisone, acetaminophen, metronidazole, phentermine, and azithromycin?

Terbinafine has no known serious drug interactions with ibuprofen, amoxicillin, prednisone, acetaminophen, metronidazole, phentermine, or azithromycin. However, it's essential to inform your doctor about all medications you are currently taking to avoid potential interactions.

Can I take terbinafine/Lamisil with alcohol?

The effect of alcohol during terbinafine treatment is not well-studied. It is best to consult your doctor regarding alcohol consumption while taking terbinafine.

Does terbinafine interfere with birth control?

Concomitant use of terbinafine with birth control medications (oral contraceptives) may cause disturbances in menstrual periods.

Does terbinafine treat yeast infections/thrush/tinea versicolor?

Terbinafine is used to treat fungal infections affecting nails, toenails, and skin. It is not the preferred antifungal for yeast infections such as thrush (yeast infection of the skin) and tinea versicolor (a yeast infection characterized by discolored skin in certain areas).

Can terbinafine cause constipation/hair loss/weight gain/increase blood pressure/autism/stop contractions/hyperglycemia/respiratory depression?

Terbinafine does not typically cause constipation, hair loss, weight gain, increase in blood pressure, autism, stop contractions, hyperglycemia, or respiratory depression.

How long can I take terbinafine?

The duration of terbinafine treatment varies depending on the severity of the infection and individual responses. Follow your doctor's advice regarding the duration of use.