Nexpro (Esomeprazole)

Before taking this medicine

You should not use Nexpro if you are allergic to esomeprazole or to similar medicines such as lansoprazole (Prevacid), omeprazole (Prilosec, Zegerid), pantoprazole (Protonix), or rabeprazole (AcipHex). Heartburn is often confused with the first symptoms of a heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, and a general ill feeling. To make sure Nexpro is safe for you, tell your doctor if you have: severe liver disease; osteoporosis; low bone mineral density (osteopenia); or low levels of magnesium in your blood.

Taking a proton pump inhibitor such as Nexpro may increase your risk of bone fracture in the hip, wrist, or spine. This effect has occurred mostly in people who have taken the medicine long term or at high doses, and in those who are age 50 and older. It is not clear whether Nexpro is the actual cause of an increased risk of fracture. It is not known whether Nexpro will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether esomeprazole passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I take Nexpro?

Take Nexpro exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. This medicine is usually given for 4 to 8 weeks only. Your doctor may recommend a second course of treatment if you need additional healing time. Take each dose with a full glass (8 ounces) of water. Nexpro should be taken at least one hour before a meal. Do not crush or chew a delayed-release capsule. However to make swallowing easier, you may open the Nexpro capsule and sprinkle the medicine into a spoonful of pudding or applesauce. Swallow right away without chewing. Do not save the mixture for later use. Nexpro can be given through a nasogastric (NG) feeding tube. Open the capsule and sprinkle the medicine into a 60-milliliter syringe. Mix in 50 milliliters of water. Place the plunger into the syringe and shake the mixture well. Make sure there are no medicine granules stuck in the tip of the syringe. Attach the syringe to the NG tube and push the plunger down to empty the syringe into the tube. Then flush the tube with more water to wash the contents down.

Take this medicine for the full prescribed length of time. Your symptoms may improve before the condition is fully treated. If you use Nexpro for longer than 3 years, you could develop a vitamin B-12 deficiency. Talk to your doctor about how to manage this condition if you develop it. Call your doctor if your symptoms do not improve or if they get worse while you are taking this medicine. Nexpro can cause unusual results with certain medical tests, and you may need to stop using the medicine for a short time before a test. Tell any doctor who treats you that you are using this medicine. Store at room temperature away from moisture and heat.

Side effects of Nexpro (Esomeprazole) 

Get emergency medical help if you have signs of an allergic reaction to Nexpro: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: severe stomach pain, diarrhea that is watery or bloody; seizure (convulsions); kidney problems - urinating more or less than usual, blood in your urine, swelling, rapid weight gain; or symptoms of low magnesium - dizziness, confusion; fast or uneven heart rate; tremors (shaking) or jerking muscle movements; feeling jittery;muscle cramps, muscle spasms in your hands and feet; cough or choking feeling. Common Nexpro side effects may include: headache, drowsiness; mild diarrhea; nausea, stomach pain, gas, constipation; or dry mouth. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. 

Precautions of Nexpro (Esomeprazole) 

• Prior to taking esomeprazole, let your primary care physician or drug specialist know if you are sensitive to it; or to other PPIs (like lansoprazole, omeprazole); or then again on the off chance that you have some other sensitivities. This item might contain inert fixings, which can cause hypersensitive responses or different issues. Converse with your drug specialist for additional subtleties.
• Prior to utilizing this prescription, tell your primary care physician or drug specialist your clinical history, particularly of: liver illness, lupus.
• A few side effects may really be indications of a more difficult condition. Move clinical assistance immediately assuming that you have: indigestion with discombobulation/perspiring/unsteadiness, chest/jaw/arm/shoulder torment (particularly with windedness, strange perspiring), unexplained weight reduction.
• Furthermore, before you self-treat with this medicine, move clinical assistance immediately assuming that you have any of these indications of a difficult condition: inconvenience/torment gulping food, ridiculous regurgitation, upchuck that seems to be coffee beans, horrendous/dark stools, indigestion for north of 90 days, successive chest torment, incessant wheezing (particularly with indigestion), sickness/spewing, stomach torment.
• Prior to having a medical procedure, inform your primary care physician or dental specialist regarding every one of the items you use (counting professionally prescribed drugs, nonprescription medications, and natural items).
• Proton siphon inhibitors, (for example, esomeprazole) may expand your gamble for bone breaks, particularly with longer use, higher portions, and in more established grown-ups. Talk with your primary care physician or drug specialist about ways of forestalling bone misfortune/crack, like by taking calcium, (for example, calcium citrate) and vitamin D enhancements.
• More seasoned grown-ups might be more delicate to the results of this medication, particularly bone misfortune and breaks (see above), and C. difficile disease (see Side Effects area).
• Youngsters might be more delicate to the symptoms of this medication, particularly fever, hack, and diseases of the nose/throat/aviation routes.
• During pregnancy, this medicine ought to be utilized just when obviously required. Examine the dangers and advantages with your primary care physician.
• It is obscure assuming that this prescription passes into bosom milk. Be that as it may, comparative medications pass into bosom milk. The consequences for a nursing newborn child are obscure. Counsel your PCP before bosom taking care of. 

Interaction of Nexpro (Esomeprazole)

Drug collaborations might change how your prescriptions work or increment your gamble for serious incidental effects. Keep a rundown of the multitude of items you use and offer it with your primary care physician and drug specialist. Try not to begin, stop, or change the measurements of any prescriptions without your PCP's endorsement.A few items that might communicate with this medication include: cilostazol, clopidogrel, methotrexate (particularly high-portion treatment), rifampin, St John's wort.A few items need stomach corrosive so the body can retain them appropriately. Esomeprazole diminishes stomach corrosive, so it might change how well these items work. A few impacted items incorporate atazanavir, erlotinib, nelfinavir, rilpivirine, certain azole antifungals (itraconazole, ketoconazole, posaconazole), levoketoconazole, pazopanib, among others.Esomeprazole is basically the same as omeprazole. Utilize no drugs containing omeprazole while utilizing esomeprazole.

FAQs: 

What is the best opportunity to take esomeprazole?

You'll ordinarily take esomeprazole one time each day, before anything else. You can take it regardless of food. On the off chance that you take esomeprazole two times per day, take 1 portion in the first part of the day and 1 portion at night. Gulp down tablets and containers with a beverage of water (non-bubbly).

What amount of time might you at any point require esomeprazole for?

To treat erosive esophagitis: Adults — 20 or 40 milligrams (mg) when daily for 4 to about two months. Your PCP might change your portion depending on the situation. To keep erosive esophagitis from returning, your primary care physician might believe that you should require 20 mg once per day for as long as a half year.

Who shouldn't take esomeprazole?

foundational lupus erythematosus, an immune system illness. osteoporosis, a state of powerless bones. a wrecked bone. CYP2C19 poor metabolizer.