Brufen (Ibuprofen) Used to Reduce Fever, Relieve Mild to Moderate Pain, and Ease Inflammation
Brufen (Ibuprofen) is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, inflammation, and fever. It may be used for headaches, toothache, muscle and joint pain, menstrual cramps, back pain, and other inflammatory or painful conditions. Ibuprofen works by reducing the production of prostaglandins, substances involved in pain, inflammation, and fever. Use Brufen at the recommended dose and for the shortest duration necessary.
Product Overview
Brufen contains Ibuprofen, a non-steroidal anti-inflammatory drug (NSAID). It provides analgesic (pain-relieving), anti-inflammatory, and antipyretic (fever-reducing) effects. It works by inhibiting cyclooxygenase (COX) enzymes, which reduces the production of prostaglandins involved in pain, inflammation, and fever— offering fast, effective relief from a broad range of everyday and chronic conditions.
Brufen is available in different strengths and dosage forms. Always check the strength and formulation on your specific product before taking it.
Product Information
| Product Name | Brufen |
| Generic Name | Ibuprofen |
| Drug Class | Non-Steroidal Anti-Inflammatory Drug (NSAID) |
| Therapeutic Action | Analgesic, Anti-inflammatory, Antipyretic |
| Route | Oral, depending on formulation |
| Prescription Status | Depends on strength and local regulations |
How Brufen Works
Ibuprofen blocks the activity of COX-1 and COX-2 enzymes, reducing prostaglandin production. Prostaglandins contribute to pain, swelling, and elevated body temperature. By lowering their production, Brufen helps relieve pain and inflammation and reduce fever.
Key Benefits
- Relieves mild to moderate pain.
- Helps reduce inflammation and swelling.
- Helps lower fever.
- Can provide relief from several common musculoskeletal and inflammatory conditions.
- Available in different formulations and strengths for different treatment needs.
Available Forms
Brufen is available in multiple formulations to suit different needs, including tablets, syrup, and retard (extended-release) tablets, allowing flexible dosing across age groups and conditions.
Directions for Use
Take Brufen with food or a glass of milk to minimize stomach discomfort. Use the lowest effective dose for the shortest duration necessary, as directed by your physician. Do not exceed the recommended dosage.
Storage
Store in a cool, dry place away from direct sunlight and out of reach of children.
Important Information
Brufen should be used at the lowest effective dose for the shortest appropriate duration. Higher doses or prolonged use can increase the risk of stomach bleeding, kidney problems, cardiovascular events, and other NSAID-related complications.
Precautions
Precautions for Brufen (Ibuprofen)
Before taking Brufen, tell your doctor or pharmacist about your medical history and all medicines you use.
Important Precautions
- Do not take Brufen if you have previously experienced an allergic reaction to ibuprofen, aspirin, or other NSAIDs.
- Inform your doctor if you have or have had a stomach ulcer or gastrointestinal bleeding.
- Use caution if you have kidney, liver, or heart disease.
- Tell your healthcare provider if you have high blood pressure, asthma, or a history of cardiovascular disease.
- Avoid taking Brufen with other NSAIDs unless specifically advised by your doctor.
- Use the lowest effective dose for the shortest necessary period.
- Older adults may have a higher risk of gastrointestinal bleeding and kidney-related adverse effects.
- Tell your doctor if you are dehydrated, particularly before taking ibuprofen.
- Consult your healthcare provider before using Brufen during pregnancy. Ibuprofen should generally be avoided from 20 weeks of pregnancy onward unless specifically advised, and it should not be used during the third trimester.
- Discuss breastfeeding with your healthcare provider before use.
Stop and Seek Medical Attention If You Experience
- Black or bloody stools
- Vomiting blood
- Severe stomach pain
- Difficulty breathing or facial swelling
- Chest pain
- Sudden weakness or speech difficulties
- Severe skin rash or blistering
- Significantly reduced urine output
Usage
How to Use Brufen
- Take Brufen exactly as directed by your healthcare provider or according to the instructions for your specific formulation.
- Swallow oral tablets with water.
- Taking ibuprofen with or after food may help reduce stomach irritation.
- Do not exceed the recommended dose.
- Use the lowest effective dose for the shortest necessary duration.
- Do not combine it with other NSAIDs unless your doctor specifically recommends this.
If You Miss a Dose
If Brufen has been prescribed on a regular schedule, take the missed dose when you remember unless it is nearly time for the next dose. Do not take two doses together to make up for a missed dose.
Uses
Brufen is used to relieve pain, inflammation, and fever associated with various conditions.
Common Uses
- Headache and migraine-related pain
- Toothache
- Back pain
- Muscle aches and strains
- Joint and inflammatory pain
- Menstrual cramps
- Mild to moderate musculoskeletal pain
- Fever associated with common illnesses
- Pain and inflammation associated with conditions such as arthritis
Side Effects
Like other NSAIDs, Brufen can cause side effects. Many people experience no significant problems when using it appropriately, but the risk increases with higher doses and prolonged treatment.
Common Side Effects
- Indigestion
- Stomach discomfort or abdominal pain
- Nausea
- Vomiting
- Heartburn
- Diarrhea or constipation
- Headache
- Dizziness
- Mild skin rash
Serious Side Effects
Seek immediate medical attention if you experience:
- Gastrointestinal bleeding: black stools, blood in stools, or vomiting blood.
- Severe allergic reaction: swelling of the face or throat, difficulty breathing, or severe rash.
- Kidney problems: significantly reduced urination, swelling, or unusual tiredness.
- Liver problems: yellowing of the skin or eyes or unusually dark urine.
- Cardiovascular problems: chest pain, sudden weakness, or difficulty speaking.
- Severe skin reactions: blistering, peeling skin, or extensive rash.
Long-Term or High-Dose Use
Prolonged or high-dose NSAID use may increase the risk of stomach ulcers or bleeding, kidney impairment, high blood pressure, fluid retention, and cardiovascular events. Regular medical monitoring may be appropriate for people who require long-term treatment.
FAQs
Interactions
Ibuprofen can interact with medicines that affect the stomach, kidneys, blood pressure, blood clotting, or cardiovascular system.
Important Drug Interactions
1. Other NSAIDs
- Avoid combining Brufen with other NSAIDs, such as naproxen or diclofenac, unless specifically advised by a healthcare professional. Combining them can increase the risk of gastrointestinal and kidney-related side effects.
2. Aspirin
- Ibuprofen may interact with low-dose aspirin and can increase gastrointestinal risks. It may also interfere with aspirin's antiplatelet effect depending on timing and use.
3. Blood Thinners
- Medicines such as warfarin, apixaban, rivaroxaban, and other anticoagulants can increase the risk of bleeding when combined with ibuprofen.
4. Corticosteroids
- Medicines such as prednisolone may increase the risk of stomach ulcers and gastrointestinal bleeding when taken with ibuprofen.
5. Blood Pressure Medicines
- Ibuprofen may reduce the effectiveness of some antihypertensive medicines and may increase the risk of kidney problems in susceptible patients.
6. Diuretics
- Ibuprofen may reduce the effect of some diuretics and can increase the risk of kidney impairment.
7. ACE Inhibitors and ARBs
- Combining NSAIDs with ACE inhibitors or angiotensin receptor blockers may affect blood pressure control and kidney function.
8. Lithium and Methotrexate
- Ibuprofen can increase exposure to certain medicines, including lithium and methotrexate, potentially increasing their toxicity. Medical supervision is important when these medicines are combined.
9. Certain Antidepressants
- SSRIs and other medicines that affect platelet function may increase the risk of gastrointestinal bleeding when taken with NSAIDs.
Alcohol
Avoid excessive alcohol while taking Brufen. Alcohol can increase stomach irritation and may further increase the risk of gastrointestinal bleeding.
Important Note
Always tell your healthcare provider about all prescription medicines, over-the-counter products, vitamins, and herbal supplements you take before starting Brufen.
| Manufacturer | : | A. Menarini India Pvt Ltdine HCL) |
| Trade Name | : | Advil |
| Generic Search | : | Ibuprofen |
| Strength | : | 200 mg, 400 mg, 600 mg, |
Certified Content
Dr. Priya Nair
Clinical Pharmacist & Senior Drug Information Specialist | 9 years
Pharm.D. (Doctor of Pharmacy)
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