Zoetis Simparica Trio Tick and Flea Control Tablet for Dogs (SAROLANER + MOXIDECTIN + PYRANTEL)
Simparica Trio by Zoetis is a prescription chewable tablet formulated for dogs to provide comprehensive parasite protection. Combining three active ingredients—Sarolaner, Moxidectin, and Pyrantel—this all-in-one monthly treatment is designed for dog owners who seek effective, easy-to-administer protection against fleas, ticks, heartworms, roundworms, and hookworms.
Suitable for puppies and dogs 8 weeks of age and older and weighing 1.25 kg (2.8 lbs) or more, Simparica Trio is a trusted solution recommended by veterinarians worldwide.
Description
Active Ingredients per chewable tablet:
- Sarolaner: An isoxazoline-class compound effective against fleas and ticks by interfering with the nervous system of parasites.
- Moxidectin: A macrocyclic lactone that targets and prevents heartworm disease by killing the larval stages.
- Pyrantel (as embonate): A well-known anthelmintic agent that treats intestinal roundworms and hookworms.
Form: Chewable tablet
Flavor: Liver-flavored, palatable for most dogs
Frequency: Administer once a month, with or without food
Precautions:
Warnings:
- For use in dogs only. Not for human or feline use.
- Keep out of reach of children.
- Do not administer to puppies under 8 weeks of age or dogs under 1.25 kg body weight.
Who Should Not Use This Product:
- Dogs with a history of neurological disorders, especially those prone to seizures.
- Dogs with known hypersensitivity to isoxazoline compounds.
- Breeding, pregnant, or lactating dogs—use only under veterinary supervision.
Uses:
Simparica Trio is indicated for the prevention, control, and treatment of the following conditions in dogs:
- Flea infestations (Ctenocephalides felis)
- Tick infestations (including Ixodes scapularis, Dermacentor variabilis, Amblyomma americanum, Rhipicephalus sanguineus)
- Heartworm disease prevention (Dirofilaria immitis)
- Treatment and control of roundworms (Toxocara canis, Toxascaris leonina)
- Treatment and control of hookworms (Ancylostoma caninum)
Side Effects:
Most dogs tolerate Simparica Trio well. However, side effects may occur, especially if the dog has a sensitivity to any of the ingredients.
Common Side Effects (mild to moderate):
- Vomiting
- Diarrhea
- Lethargy
- Loss of appetite
- Tremors
Rare/Serious Side Effects (seek veterinary advice immediately):
- Seizures
- Hypersalivation
- Uncoordinated movements
- Allergic reactions (swelling, difficulty breathing)
If your dog exhibits severe reactions or persistent symptoms, consult your veterinarian immediately.
FAQs:
1. How often should I give Simparica Trio to my dog?
Once every 30 days. Monthly administration is essential for continuous protection.
2. Can I give Simparica Trio with food?
Yes, Simparica Trio can be given with or without food.
3. Is Simparica Trio safe for all dog breeds?
Yes, but dogs with a history of seizures or neurological conditions should only be treated under veterinary supervision.
4. What should I do if I miss a dose?
Administer the missed dose as soon as possible. Resume monthly dosing schedule. Avoid doubling the dose.
5. Does Simparica Trio protect against tapeworms?
No, it does not. For tapeworm treatment, a separate deworming medication is required.
Interactions:
Simparica Trio may interact with other medications. Use caution if your dog is taking:
- Other isoxazoline-containing products (e.g., NexGard, Bravecto)
- Macrocyclic lactones (e.g., ivermectin-based heartworm preventives)
- CNS-affecting drugs—due to potential for increased neurological side effects
Always inform your veterinarian of all medications or supplements your dog is taking.
| Manufacturer | : | Zoetis |
| Trade Name | : | |
| Generic Search | : | Sarolaner + Moxidectin + Pyrantel |
| Strength | : |
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