Rapacan 1 Tablet (Sirolimus)
Rapacan 1 mg (sirolimus) is an immunosuppressant used to prevent organ rejection after a kidney transplant. Rapacan (Sirolimus) may also be used to treat other conditions as determined by your doctor.
| USA Brand Name | Rapamune |
| Strength | 1 mg |
| Generic Name | Sirolimus |
| Manufacturer | Eris Lifesciences Ltd |
| Storage | Store Below 30° C |
What is Rapacan (sirolimus)?
Rapacan, also known by the generic name Sirolimus, is used for the prevention of organ rejection in transplant patients. It regulates the body’s immune response, so the body can accept the new organ.
Rapacan 1 tablet contains the active ingredient sirolimus, which belongs to a group of medications called immunosuppressants. Sirolimus is used to prevent the body from rejecting a transplanted organ, such as a kidney, liver, or heart. Inhibiting the immune system helps stop the body from attacking and rejecting the transplanted organ, which is how sirolimum works. T-cells, a group of white blood cells crucial to the immune system's operation, are the main target of sirolimus.
Sirolimus vs Tacrolimus
How do Sirolimus and Tacrolimus work?
- Sirolimus: Inhibits T-cell activation and proliferation by blocking mTOR, crucial for cell cycle progression.
- Tacrolimus: Inhibits T-cell activation by binding to FKBP, blocking the calcineurin pathway.
Side Effects:
- Sirolimus: Can cause increased cholesterol/triglyceride levels, delayed wound healing, and mouth sores.
- Tacrolimus: May cause high blood sugar, kidney toxicity, and neurological side effects like tremors and headaches.
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Precautions for Rapacan 1 Tablet (Sirolimus) include:
Medical History: Inform your healthcare provider about any medical conditions you have, especially liver disease, kidney disease, high cholesterol, diabetes, or any infections.
Regular Monitoring: Your healthcare provider may recommend regular blood tests to monitor your kidney function, cholesterol levels, and sirolimus levels while taking the medication.
Immune System Suppression: Sirolimus suppresses the immune system, increasing the risk of infection. Avoid contact with people who have contagious illnesses, and promptly report any signs of infection to your healthcare provider.
Avoid Grapefruit: Grapefruit and grapefruit juice may interact with sirolimus, affecting its effectiveness or increasing the risk of side effects. Avoid consuming grapefruit or grapefruit juice while taking this medication.
Pregnancy and Breastfeeding: Sirolimus may harm an unborn baby. It is not recommended during pregnancy. If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of sirolimus with your healthcare provider.
Avoid Vaccines: Avoid live vaccines while taking sirolimus, as they may not be as effective and could potentially cause infection.
Avoid Alcohol and Tobacco: Limit alcohol consumption and avoid tobacco products while taking sirolimus, as they may worsen certain side effects.
Storage: Store sirolimus tablets at room temperature away from moisture and heat. Keep them out of reach of children and pets.
Sirolimus 1mg uses
Rapacan 1 tablet contains the active ingredient Sirolimus, which is an immunosuppressive medication used to prevent the body from rejecting a transplanted organ, such as a kidney, liver, or heart. Sirolimus is usually used in combination with other immunosuppressive medications to prevent organ rejection in people who have undergone solid organ transplant surgery. However, the use of Sirolimus for these conditions is not well established, and you should consult with your doctor before using it for any other purpose than organ transplant rejection.
Sirolimus dosage
Rapacan 1 tablet is typically taken once a day, at the same time each day. It's critical to follow your doctor's instructions and not stop taking the prescription without first speaking with them.If you experience any side effects while taking Rapacan 1 tablet, it is important to notify your doctor as soon as possible. To assist you manage any adverse effects you may encounter, your doctor may change the medicine you are taking or modify your dosage.
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Sirolimus side effects
Avoid exposure to sunlight or tanning beds. Sirolimus may increase your risk of skin cancer. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. If this medicine gets into your eyes, rinse them with plain water. Grapefruit and grapefruit juice may interact with sirolimus and could lead to potentially dangerous effects. Do not mix this medicine with grapefruit juice. Avoid eating grapefruit or drinking grapefruit juice while you are taking sirolimus. Do not receive a "live" vaccine while using sirolimus. The vaccine may not work as well during this time, and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.
FAQs
Q: What is Rapacan 1 tablet used for?
A: Prevents organ rejection after transplant.
Q: How should I take Rapacan 1 tablet?
A: Take once daily, same time each day. Follow doctor's instructions.
Q: What are the possible side effects of Rapacan?
A: Headache, dizziness, nausea, vomiting, diarrhea, stomach pain, infection risk, low blood cell counts.
Q: What precautions should I take while taking Rapacan 1 tablet?
A: Inform doctor of allergies, medical conditions, and other medications. Avoid sunlight, practice good hygiene, and report infection symptoms.
Q: What happens if I miss a dose?
A: Take as soon as remembered. Skip if near next dose. Don't double up.
Q: What happens if I overdose?
A: Seek emergency medical assistance.
Q: Can sirolimus cause cancer?
A: Slightly increased risk of skin cancer, lymphoma, and Kaposi's sarcoma, monitored by healthcare providers.
Interactions for Rapacan 1 Tablet (Sirolimus) include:
Immunosuppressants: Concurrent use of sirolimus with other immunosuppressant medications, such as cyclosporine or tacrolimus, may increase the risk of immune suppression and infection. Close monitoring of immune function and adjustment of doses may be necessary.
Grapefruit and Grapefruit Juice: Grapefruit and grapefruit juice can inhibit CYP3A4 metabolism, potentially increasing sirolimus levels in the blood and the risk of side effects. Avoid consuming grapefruit or grapefruit juice while taking sirolimus.
Certain antifungal medications, such as fluconazole or voriconazole, may interact with sirolimus, leading to increased sirolimus levels in the blood. Close monitoring and possible dose adjustments may be necessary.
Antifungal Agents: Sirolimus may increase the levels of statin medications used to lower cholesterol, such as atorvastatin or simvastatin, increasing the risk of statin-related side effects, including muscle toxicity. Regular monitoring of cholesterol levels and muscle function is recommended if using these medications together.
Tacrolimus: Concurrent use of sirolimus with tacrolimus may increase the risk of kidney toxicity. Close monitoring of kidney function is recommended if using these medications together.
Antibiotics: Certain antibiotics, such as erythromycin or clarithromycin, may interact with sirolimus, leading to increased sirolimus levels in the blood. Close monitoring and possible dose adjustments may be necessary.
| Manufacturer | : | Eris Lifesciences Ltd |
| Equivalent Brand | : | Rapamune |
| Generic Search | : | Sirolimus |
| Strength | : | 1 mg |
