Polaramine Tablet (Dexchlorpheniramine) | Used for Allergic Rhinitis (Hay Fever) and Urticaria

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RP0003
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Polaramine 2mg Tablet is an effective antihistamine used to treat allergy symptoms such as sneezing, runny nose, itchy eyes, skin rashes, and hives. It works by blocking histamine, a substance responsible for allergy symptoms, providing effective relief from allergic rhinitis and other allergic reactions. Available online for fast and convenient purchase. 

 

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Polaramine 2mg Tablet (Dexchlorpheniramine)
PackageQTYPriceAdd To Cart
30 Tablet\s $11.10
60 Tablet\s $22.20
90 Tablet\s $33.30

Product Overview

Polaramine 2mg Tablet is used for fast relief from allergic reactions such as hay fever, hives, skin rashes, and insect bites. Polaramine is a high-potency antihistamine containing Dexchlorpheniramine, which is the active dextrorotatory isomer of chlorpheniramine. It is designed to provide effective relief from a wide range of allergic reactions and respiratory symptoms. By specifically blocking the H1-histamine receptors, Polaramine prevents the physiological effects of histamine release, such as itching, swelling, and excessive secretion. It is widely recognized for its fast-acting relief and its versatility in treating both seasonal allergies and acute skin-related allergic responses.

Product Composition

  • Active Ingredient: Dexchlorpheniramine Maleate
  • Strength: Commonly available in 2 mg tablets
  • Dosage Form: Oral tablets
  • Pharmacological Class: Antihistamine (H1-receptor antagonist)
  • Chemical Group: Propylamine derivative

Product Specification

FeatureDetails
Primary IndicationAllergic Rhinitis, Urticaria, & Hay Fever
Onset of ActionApproximately 15 to 30 minutes
Duration of Action4 to 6 hours
Route of AdministrationOral
StorageStore below 25°C in a dry place

 

Mechanism of Action

  • Competitive H1-Inhibition: Competes with free histamine for binding at H1-receptor sites in the GI tract, uterus, large blood vessels, and bronchial muscle.
  • Capillary Permeability Reduction: Reduces the leakage of fluid from blood vessels into the surrounding tissue, which prevents the formation of "wheals" and swelling.
  • Anticholinergic Activity: Exerts a mild drying effect on the mucous membranes, helping to clear runny noses and watery eyes.
  • Sensory Nerve Blockade: Indirectly reduces the stimulation of sensory nerve endings, which effectively stops the sensation of itching (pruritus).
  • High-Affinity Binding: Because it uses the active "Dex" isomer, it provides a more targeted response at lower concentrations compared to standard chlorpheniramine.

Key Benefits

  • Rapid Symptom Relief: Works quickly to address acute allergic symptoms like sneezing, itching, and hives.
  • Broad Allergy Coverage: Effective against various triggers, including pollen, pet dander, dust, and insect bites.
  • Skin & Respiratory Support: Simultaneously manages skin rashes (urticaria) and nasal symptoms (rhinitis).
  • Proven Safety Profile: A well-established medication that has been used for decades to manage mild to moderate allergic reactions.
  • Flexible Usage: Can be used on an "as-needed" basis for temporary relief or as part of a regular routine during allergy season.

Precautions

General Precautions

  • Take Polaramine Tablet (Dexchlorpheniramine) exactly as prescribed by your doctor
  • Do not exceed the recommended dose as it may cause excessive sedation
  • May cause drowsiness; avoid driving or operating machinery
  • Avoid use with alcohol or other sedatives

Medical History Precautions

  • Inform your doctor if you have glaucoma or increased intraocular pressure
  • Tell your doctor if you have prostate enlargement or urinary retention
  • Disclose any history of asthma or chronic respiratory disease
  • Inform your doctor if you have liver disease

Elderly and Pediatric Precautions

  • Use with caution in elderly patients due to increased risk of sedation and confusion
  • Use in children only under medical supervision

Drug and Health Safety

 
Condition / SituationPrecaution
GlaucomaMay worsen intraocular pressure
Prostate enlargementMay cause difficulty in urination
Respiratory diseasesUse with caution due to potential breathing effects
Liver impairmentRequires dose adjustment and monitoring
Pregnancy & breastfeedingUse only if prescribed by doctor

Usage

Dosage and Administration

  • Adult Dosage: The typical dose is 2 mg taken every 6 hours.

  • Maximum Limit: Do not exceed 12 mg (6 tablets) in a 24-hour period.

  • Pediatric Dosing: Children aged 6 to 12 years usually take 1 mg (half a tablet) every 6 hours.

  • Method: Swallow the tablet with water. It can be taken with or without food.

  • Symptomatic Timing: Take the dose as soon as allergy symptoms appear for the best results.

Administration Guidelines

ScenarioRecommendation
DrowsinessTake the dose in the evening if it causes significant sleepiness during the day.
Dry MouthSuck on sugarless hard candy or sip water to relieve dryness in the mouth and throat.
Missed DoseTake it as soon as you remember. If it is nearly time for the next dose, skip the missed one.
AlcoholAvoid all alcoholic beverages as they increase the risk of severe sedation.

Uses

  • Allergic Rhinitis Management: Relieves sneezing, itchy nose, and runny nose caused by seasonal or year-round allergies.

  • Urticaria Treatment: Effectively reduces the redness, swelling, and intense itching associated with hives.

  • Allergic Conjunctivitis: Helps stop the itching, redness, and excessive tearing of the eyes.

  • Relief from Insect Bites: Minimizes the localized allergic skin reaction and itching following bites or stings.

  • Management of Pruritus: Used to treat general itching associated with various skin conditions or drug reactions.

  • Hay Fever Relief: Controls the multi-symptom respiratory response to pollen, grass, and mold spores.

  • Dermatitis Support: Assists in reducing the inflammatory response in allergic contact dermatitis.

Side Effects

Polaramine Tablet (Dexchlorpheniramine) is generally effective for allergy relief, but some patients may experience side effects, especially due to its sedative antihistamine action.

Common Side Effects

  • Drowsiness or sedation
  • Dry mouth, nose, or throat
  • Dizziness
  • Blurred vision
  • Fatigue or sleepiness

Less Common Side Effects

  • Nausea or stomach discomfort
  • Constipation
  • Headache
  • Restlessness or irritability (especially in children)
  • Difficulty concentrating

Serious Side Effects

Serious ConditionSymptoms
Severe sedationExcessive sleepiness, confusion, difficulty staying awake
Allergic reactionRash, swelling of face/lips/tongue, difficulty breathing
Urinary retentionDifficulty urinating, lower abdominal discomfort
Glaucoma worseningEye pain, blurred vision, increased eye pressure
CNS effectsSevere dizziness, confusion, hallucinations (rare)
 

 

Important Advice

  • Avoid alcohol and other sedatives while taking this medicine
  • Do not drive or operate machinery if drowsiness occurs
  • Use caution in elderly patients due to increased sensitivity
  • Do not exceed the prescribed dose
  • Seek medical attention if severe allergic reactions or confusion occur

FAQs

Q: What is Polaramine used for?

A: It is used to treat symptoms of hay fever and allergies. This includes sneezing, watery eyes, runny nose, and itchy skin rashes or hives.

Q: How quickly does it start to work?

A: Most people feel relief within 15 to 30 minutes after taking a dose. The effects typically last for about 4 to 6 hours.

Q: Will this medication make me drowsy?

A: Yes. Polaramine is a sedating antihistamine. It may cause drowsiness or blurred vision, so you should avoid driving or operating machinery until you know how it affects you.

Q: Can I take this with alcohol?

A: No. Alcohol can significantly increase the sedative effects of the medication, making you much more drowsy or dizzy.

Q: How many tablets can I take in one day?

A: For adults, the usual dose is one tablet every 6 hours. Do not exceed the maximum daily limit stated on the packaging or prescribed by your doctor.

Q: Can children take Polaramine tablets?

A: Tablets are generally for adults and older children. For younger children, a syrup form is usually preferred to ensure the correct dose. Check the label for age restrictions.

Q: What are the common side effects?

A: Along with sleepiness, you may experience a dry mouth, nose, or throat. Some people may also feel slight dizziness or nausea.

Q: Can I take this while pregnant?

A: You should consult your doctor before use. While it has been used for many years, a healthcare professional will help determine if it is appropriate for your specific situation.

Q: Is it safe to take with other cold or allergy medicines?

A: You should check with a pharmacist first. Many "multi-symptom" cold medicines already contain an antihistamine, and taking both could lead to an accidental overdose.

Interactions

Drug Interactions

Medicine / Drug ClassInteraction Effect
CNS depressants (benzodiazepines, sleeping pills, opioids)Increased drowsiness, sedation, and risk of respiratory depression
AlcoholStrongly increases sedation, dizziness, and impaired coordination
Other antihistaminesAdditive side effects such as drowsiness and dry mouth
Tricyclic antidepressantsIncreased anticholinergic effects (dry mouth, constipation, confusion)
MAO inhibitorsMay intensify antihistamine and anticholinergic effects
 

 

Food and Lifestyle Interactions

  • Alcohol should be strictly avoided due to increased sedation
  • Driving or operating machinery may be unsafe due to drowsiness
  • Caffeine may partially reduce drowsiness but does not eliminate sedative effects

Disease Interactions

  • Glaucoma may worsen due to increased intraocular pressure risk
  • Prostate enlargement may lead to urinary retention
  • Liver impairment may increase drug accumulation
  • Respiratory conditions may be aggravated in sensitive patients

Important Clinical Considerations

  • Inform your doctor about all medications you are taking
  • Avoid combining with multiple sedating medicines unless prescribed
  • Use caution in elderly patients due to increased sensitivity
  • Monitor for excessive sedation, confusion, or urinary difficulty
  • Seek medical advice if severe side effects occur or symptoms worsen
More Information
Manufacturer:Fulford India Ltd
Trade Name:RyClora
Generic Search:Dexchlorpheniramine
Strength:2mg
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