Nailon - Ciclopirox Nail Lacquer | Penlac Nail Lacquer | Treat Fungal Skin and Nail Infections
Nailon Nail Lacquer, featuring the antifungal agent Ciclopirox, is a topical solution, cream, or gel that inhibits fungus growth. Athlete's foot, jock itch, ringworm, and yeast infections are among the fungal skin illnesses on toes and fingernails that it successfully treats.
Product Overview
Nailon is a specialized antifungal nail lacquer containing Ciclopirox, an antifungal agent is specifically formulated to treat fungal infections of the fingernails and toenails (onychomycosis) without the need for systemic oral medications. Unlike creams or ointments, this lacquer is designed to be painted directly onto the nail plate, where it forms a hard, clear film. This film acts as a reservoir, allowing the active ingredient to penetrate deep through the nail layers to reach the nail bed where the fungus resides. Nailon provides a convenient, localized treatment option that targets the infection at its source while protecting the nail from further fungal spread.
Product Composition
- Active Ingredient: Ciclopirox
- Concentration: 8% w/v (weight/volume)
- Base: Volatile lacquer vehicle (fast-drying)
- Film Formers: Polymers that ensure the medication adheres to the nail surface
- Solvents: Isopropyl alcohol and other agents to facilitate penetration
Product Specification
| Feature | Specification |
| Therapeutic Class | Topical Antifungal |
| Pharmacological Action | Chelating Agent / Fungicidal |
| Application Form | Topical Nail Lacquer |
| Storage | Store at room temperature (15°C to 30°C) |
| Flammability | Highly flammable; keep away from heat or flame |
| Color | Clear to slightly yellowish solution |
Mechanism of Action
- Metal Ion Chelation: Ciclopirox works by binding to essential polyvalent cations ($Fe^{3+}$ or $Al^{3+}$) within the fungal cells.
- Enzyme Inhibition: By sequestering these ions, it inhibits the activity of iron-dependent enzymes responsible for cellular respiration and nutrient transport.
- Cell Membrane Disruption: It alters the permeability of the fungal cell membrane, leading to the leakage of essential cellular components.
- Trans-ungual Penetration: The lacquer vehicle is engineered to pass through the dense keratin of the nail, reaching the fungal pathogens located beneath the nail plate.
- Broad-Spectrum Activity: It is effective against dermatophytes, yeasts, and molds that commonly cause nail infections.
Key Benefits
- Targeted Treatment: Delivers high concentrations of the antifungal directly to the site of infection.
- Non-Systemic: Because it is applied topically, it avoids the risk of liver toxicity or drug interactions associated with oral antifungal pills.
- Protective Barrier: The hardened lacquer forms a physical shield that helps prevent the spread of the fungus to adjacent nails or skin.
- Easy Application: The built-in applicator brush allows for precise and mess-free use.
- Invisible Finish: Dries clear, making it a discreet option for long-term treatment.
Usage
Effective treatment of onychomycosis requires strict adherence to a long-term application schedule. Because nails grow slowly, the medication must be applied consistently to protect the new nail growth from fungal colonization.
Dosage
The application follows a specific cycle to ensure the nail plate remains saturated with the antifungal agent.
Application Frequency: Apply the lacquer once daily, preferably before bedtime, to all affected nails.
Treatment Duration: Continue the daily applications for several months. Fingernails typically require 6 months of treatment, while toenails may require 9 to 12 months.
Removal Cycle: Once every seven days, remove all accumulated layers of the lacquer using a standard nail polish remover.
Maintenance: After the weekly removal, use a nail file or clippers to trim away any loose or diseased nail material before starting the next cycle of daily applications.
Administration
Following the correct preparation and application steps is vital for the lacquer to penetrate the dense keratin of the nail.
| Step | Action |
| Preparation | Clean and dry the nails thoroughly. Trim the nails and file down thickened areas to improve penetration. |
| Application | Use the provided brush to apply an even coat over the entire nail plate and 5mm of the surrounding skin. |
| Drying | Allow the lacquer to dry completely (about 30 to 60 seconds) before putting on socks or gloves. |
| Cleaning | Wipe the applicator brush clean before returning it to the bottle to prevent the solution from thickening. |
| Protection | Avoid washing the treated nails for at least 8 hours after application to ensure the film sets properly. |
Uses
Nailon is indicated for the topical management of fungal infections affecting the integrity of the nail structure.
Onychomycosis: Primary treatment for mild to moderate fungal infections of the fingernails and toenails caused by dermatophytes.
Tinea Unguium: Specifically targets infections that cause the nail to become brittle, thickened, or discolored (yellow, brown, or white).
Prevention of Spread: Acts as a protective barrier to prevent the fungal pathogens from migrating to healthy adjacent nails.
Localized Antifungal Therapy: Provides a safe alternative for patients who cannot take oral antifungal medications due to liver concerns or drug interactions.
Adjuvant Care: Often used in combination with professional nail debridement to accelerate the removal of infected keratin.
Yeast and Mold Infections: Effective against a broad range of non-dermatophyte molds and yeasts that can occasionally invade the nail bed.
FAQs
Q1: How to use ciclopirox nail lacquer?
Apply a thin layer to the affected nails and surrounding skin once daily, preferably at bedtime. Allow it to dry completely. After 5-7 days, remove the buildup of lacquer with alcohol and trim or file the loose parts of the nail as directed.
Q: How long does it take to see results with Nailon?
A: Fungal nail infections clear slowly. You will notice improvement as the healthy nail grows out from the base. This process can take six months for fingernails and up to a year for toenails.
Q: Can I use regular nail polish over this lacquer?
A: No, you should not apply cosmetic nail polish or artificial nails to the affected area during treatment. These products can prevent the medication from penetrating the nail and reaching the fungus.
Q: Do I need to remove the old layers of lacquer?
A: Yes, once a week, you should remove all built-up layers using a standard nail polish remover. This ensures the fresh application can bond directly to the nail surface and remain effective.
Q: What should I do if the lacquer chips?
A: If the lacquer chips or wears off between applications, simply reapply it to the affected area. Maintaining a continuous film over the nail is important for consistent treatment.
Q: Is it necessary to trim the infected nail?
A: Yes, you should regularly trim your nails and file down any thickened areas. Removing as much of the damaged nail as possible helps the lacquer reach the underlying infection more easily.
Q: Can this treatment be used for skin infections?
A: This specific lacquer is formulated only for use on the nails. If you have a fungal infection on the surrounding skin (athlete's foot), you should use a cream or spray designed for skin.
Q: How should I store the bottle to prevent it from drying out?
A: Always close the cap tightly immediately after use. Store the bottle upright in a cool, dry place, and keep it away from open flames since the solution is flammable.
Interactions
Drug Interactions
| Medicine Type | Interaction Effect |
|---|---|
| Other topical antifungal agents | May lead to overlapping effects without added benefit |
| Systemic antifungal medicines | Usually safe but may be used together in severe infections under supervision |
| Nail cosmetic products (polish, gels) | Can reduce effectiveness of Ciclopirox lacquer |
| Keratolytic agents | May increase penetration but also risk of irritation |
Disease Interactions
- Diabetes may slow healing of nail infections and require longer treatment
- Peripheral vascular disease may reduce drug effectiveness due to poor blood flow
- Immunocompromised conditions may require combination therapy
- Severe or long-standing fungal infections may need oral antifungal support
Food and Lifestyle Interactions
- No significant food interactions are known
- Keep nails dry and clean to improve treatment response
- Avoid sharing nail tools to prevent reinfection
- Wear breathable footwear to reduce fungal growth
Monitoring Advice
- Monitor nail appearance for improvement over several weeks
- Watch for signs of irritation or worsening infection
- Maintain consistent application schedule for best results
- Report lack of improvement after prolonged use to a healthcare provider
| Manufacturer | : | Apple Therapeutics, India |
| Trade Name | : | Penlac Nail Lacquer |
| Generic Search | : | Ciclopirox |
| Strength | : | 5 ml |
Latest Products
