Avonza Tablet[Lamivudine (300mg) + Tenofovir disoproxil fumarate (300mg) + Efavirenz (400mg)]

Precautions Of Avonza Tablet

• Inform your doctor if you have liver disease, kidney problems, or a history of mental health issues.
• Avoid alcohol — it may worsen liver side effects.
• Use with caution if taking other HIV or hepatitis medicines.
• Not recommended during pregnancy unless advised by a doctor.
• May cause dizziness or drowsiness — avoid driving or operating machinery.
• Regularly monitor liver enzymes and kidney function during treatment.

Usage Of  Avonza Tablet

• Take one tablet daily at bedtime or as prescribed by your doctor.
• Preferably taken on an empty stomach to minimize side effects (especially dizziness).
• Do not skip doses — adherence is critical to prevent drug resistance.
• Swallow the tablet whole with water; do not crush or chew.
• Continue regular HIV monitoring tests during treatment.

Side Effects Of  Avonza Tablet

Common side effects include:

• Dizziness or headache
• Nausea, vomiting, or diarrhea
• Trouble sleeping or vivid dreams
• Fatigue or weakness
• Rash or mild skin irritation

Serious (rare) side effects:

• Liver problems (yellowing of skin/eyes)
• Lactic acidosis (deep breathing, stomach pain, muscle pain)
• Depression or mood changes
• Signs of kidney issues (swelling, decreased urine)
• Seek medical help if any severe reactions occur.

FAQs Of  Avonza Tablet

Q1. What is Avonza Tablet used for?
It is used to treat HIV infection by reducing the virus’s activity in the body.

Q2. Can Avonza cure HIV completely?
No — it controls the virus but does not cure HIV or AIDS.

Q3. Can I take Avonza with food?
It can be taken with or without food, but empty stomach at bedtime is preferred to reduce side effects.

Q4. What should I do if I miss a dose?
Take it as soon as you remember. If it’s close to the next dose, skip the missed one. Do not double the dose.

Q5. Is Avonza safe for long-term use?
Yes, it is safe when taken under regular medical supervision with routine monitoring.

Interactions Of Avonza Tablet

1. Antiretroviral Drugs:
Avoid combining Avonza with other antiretroviral medicines containing Lamivudine, Tenofovir, or Efavirenz — this can lead to overdose or toxicity.

2. Antifungal & Antibiotic Drugs:

Rifampicin, Rifabutin, and Itraconazole can reduce Efavirenz levels, lowering its effectiveness.

Clarithromycin may also interact, requiring dose adjustments.

3. Anticonvulsants:

Phenytoin, Carbamazepine, Phenobarbital can reduce Efavirenz concentration, affecting HIV control.

4. Antidepressants / Sedatives:

Combining with benzodiazepines or antidepressants (e.g., sertraline) can increase dizziness, confusion, or sleep issues.

5. Herbal Supplements:

St. John’s Wort reduces Efavirenz levels — avoid completely.

6. Hepatitis B & C Medications:

Use cautiously with interferon-based drugs or other antivirals — may increase liver strain.

7. Alcohol:

Increases risk of liver toxicity and worsens side effects like dizziness or nausea.