Palnat 100 mg Capsule (Palbociclib)
Palnat 100 mg Capsule contains Palbociclib, a targeted therapy used to treat HR-positive, HER2-negative advanced breast cancer by slowing cancer cell growth.
Introduction of Palnat 100 mg Capsule (Palbociclib)
Palnat 100 mg Capsule contains Palbociclib, a targeted anti-cancer medicine used in the treatment of hormone receptor (HR)-positive and HER2-negative advanced or metastatic breast cancer. It belongs to a class of drugs known as CDK4/6 inhibitors, which work by blocking proteins responsible for cell cycle progression, thereby slowing down the growth and division of cancer cells.
This medicine is commonly prescribed in combination with endocrine (hormonal) therapies such as aromatase inhibitors or fulvestrant to enhance treatment effectiveness. It helps in controlling disease progression and improving progression-free survival in patients with advanced breast cancer.
Precautions of Palnat 100 mg Capsule (Palbociclib)
- Use strictly under oncologist supervision
- Regular blood tests required (monitor neutropenia)
- Avoid use during pregnancy and breastfeeding
- Use effective contraception during and after treatment
- Inform doctor about liver or kidney disorders
- Avoid grapefruit or grapefruit juice
- Do not crush, chew, or open capsules
Uses of Palnat 100 mg Capsule (Palbociclib)
- HR-positive, HER2-negative advanced breast cancer
- Metastatic breast cancer
- First-line treatment in combination with aromatase inhibitors
- Second-line treatment with fulvestrant
- Helps slow disease progression
Side Effects of Palnat 100 mg Capsule (Palbociclib)
Common side effects:
- Neutropenia (low white blood cells)
- Fatigue or weakness
- Nausea
- Hair thinning or mild hair loss
- Diarrhea
- Stomatitis (mouth sores)
Serious side effects:
- Severe infections due to low immunity
- Febrile neutropenia
- Lung inflammation (interstitial lung disease, rare)
- Liver function abnormalities
FAQs of Palnat 100 mg Capsule (Palbociclib)
Q1. What is Palnat 100 mg Capsule used for?
It is used to treat HR-positive, HER2-negative advanced or metastatic breast cancer.
Q2. How does Palbociclib work?
It blocks CDK4/6 enzymes, slowing down cancer cell division and growth.
Q3. Is Palnat taken alone?
No, it is usually taken in combination with hormonal therapy.
Q4. What is the most common side effect?
Neutropenia (low white blood cell count), which increases infection risk.
Q5. Do I need monitoring during treatment?
Yes, regular blood tests are essential to monitor blood counts and overall health.
Interactions of Palnat 100 mg Capsule (Palbociclib)
Palnat Capsule may interact with:
- Strong CYP3A inhibitors (ketoconazole, itraconazole)
- CYP3A inducers (rifampicin, carbamazepine, phenytoin)
- Hormonal therapies (used under medical supervision)
- Grapefruit products (increase drug concentration)
- Certain antibiotics, antifungals, and antivirals
| Manufacturer | : | Natco Pharma, India |
| Trade Name | : | Ibrance |
| Generic Search | : | Palbociclib |
| Strength | : | 100mg |
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