Lupirtin Capsule (Flupirtine)
Lupirtin Capsule contains Flupirtine maleate 100 mg, a non-opioid, centrally acting analgesic.
It is specially designed for adults suffering from moderate to severe acute or chronic pain, particularly musculoskeletal pain, headache, and pain after surgery or injury.
Its unique mode of action makes it suitable for patients who cannot tolerate traditional NSAIDs or opioids.
- Brand name: Lupirtin Capsule
- Generic name: Flupirtine maleate 100 mg
- Dosage form: Oral capsule
- Pharmacological class: Non-opioid analgesic & muscle relaxant
- Mechanism of action: Acts as a selective neuronal potassium channel opener (SNEPCO) and NMDA receptor antagonist, leading to effective pain relief without significant sedation or respiratory depression.
Precautions of Lupirtin Capsule :
Warnings:
- Prolonged use (more than 2 weeks) increases the risk of liver toxicity
- Liver function tests should be done before and during treatment, especially in long-term use
Who should NOT take it:
- Patients with pre-existing liver disease
- History of alcohol abuse
- Children & adolescents below 18 years
- Pregnant and breastfeeding women (unless clearly necessary, and prescribed by a doctor)
Use with caution:
- Elderly patients
- Patients taking other liver-affecting medicines
Uses of Lupirtin Capsule :
Lupirtin Capsule is used to relieve:
- Acute and chronic muscle pain
- Back pain (e.g., low back pain, cervical pain)
- Post-traumatic pain (after accidents or surgeries)
- Headache (including tension headache)
- Joint pain (e.g., osteoarthritis pain)
- Neuropathic pain in some cases, where conventional analgesics fail
Side effects of Lupirtin Capsule :
Common side effects are generally mild, but it’s important to be aware of them:
- Dizziness
- Fatigue or tiredness
- Nausea and vomiting
- Dry mouth
- Heartburn or gastric discomfort
Less common but serious:
- Liver problems (elevated liver enzymes, jaundice)
- Allergic reactions (rash, itching, swelling)
Patients should report persistent or severe side effects to their doctor immediately.
FAQs of Lupirtin Capsule :
Q: Can Lupirtin be taken on an empty stomach?
A: It can be taken with or without food, but taking it after food may reduce stomach upset.
Q: How quickly does it relieve pain?
A: Pain relief usually starts within 30–60 minutes of taking the capsule.
Q: Is it addictive?
A: Lupirtin (Flupirtine) is non-opioid and generally not addictive.
Q: How long can I take it?
A: Use is typically limited to 2 weeks or as prescribed, due to risk of liver damage.
Q: What should I do if I miss a dose?
A: Take it as soon as you remember, unless it’s almost time for your next dose. Do not double the dose.
Interactions of Lupirtin Capsule :
Lupirtin may interact with:
- Alcohol: Increases risk of liver toxicity and dizziness
- Other hepatotoxic drugs: (e.g., paracetamol, certain antibiotics, antifungals)
- Sedatives or CNS depressants: May increase drowsiness
- Anticoagulants (like warfarin): May alter their effect
Always inform your doctor about all medicines, herbal products, and supplements you are taking.
| Manufacturer | : | Lupin Pharma, India |
| Trade Name | : | |
| Generic Search | : | Flupirtine |
| Strength | : | 100mg, 400mg |
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