IVE Race 4.8 Oral Paste for Horses (Ivermectin Paste)
IVE Race 4.8 Oral Paste for Horses is a high-strength ivermectin paste formulated for oral use in horses. It’s designed as an anthelmintic and boticide, meaning it effectively treats and controls a broad range of internal parasites and bots with a single dose.
IVE Race 4.8 Oral Paste Product Overview
IVE Race 4.8 is a highly effective, broad-spectrum anthelmintic and biphonicid oral paste specifically formulated for the treatment and control of internal parasites in horses. Containing Ivermectin at a concentration of 1.87% (which delivers 4.8g of the active drug in a standard syringe), it belongs to the avermectin family of medications. This paste is a staple in equine healthcare, providing a convenient and reliable method to eliminate a wide range of harmful worms and bots that can compromise a horse's health and performance.
Product Composition
- Active Ingredient: Ivermectin (1.87% w/w)
- Total Active Weight: 4.8g per syringe
- Formulation: Palatable Oral Paste
- Pharmacological Class: Anthelmintic (Parasiticide)
- Target Species: Horses and Ponies
Product Specifications
| Feature | Details |
| Generic Name | Ivermectin Oral Paste |
| Therapeutic Category | Equine Dewormer |
| Primary Indication | Control of Large and Small Strongyles, Pinworms, and Bots |
| Dosing Mechanism | Calibrated dial-a-dose syringe based on body weight |
| Safety Profile | Safe for foals (over 6 weeks), breeding stallions, and pregnant mares |
Mechanism of Action
Ivermectin works by paralyzing and eventually killing the parasites by disrupting their nervous system:
- Glutamate-Gated Ion Channels: Ivermectin binds selectively and with high affinity to glutamate-gated chloride ion channels found in invertebrate nerve and muscle cells.
- Paralysis: This binding increases the permeability of the cell membrane to chloride ions, leading to hyperpolarization of the nerve or muscle cell.
- Expulsion: The resulting flaccid paralysis prevents the parasite from feeding or maintaining its position within the horse's digestive tract, leading to its death and natural expulsion from the body.
- Selective Toxicity: Because mammals do not have glutamate-gated chloride channels and ivermectin does not easily cross the blood-brain barrier in horses, it is highly toxic to parasites while remaining safe for the host.
Key Benefits of IVE Race 4.8 Oral Paste
- Broad-Spectrum Efficacy: Effectively targets major parasites including Large Strongyles (Strongylus edentatus), Small Strongyles, Pinworms, Ascarids, Hairworms, and Stomach Bots.
- Convenient Administration: The "dial-a-dose" syringe allows for precise measurement according to the horse's weight, reducing the risk of under-dosing or over-dosing.
- Apple-Flavored Palatability: Often formulated with flavors that horses find acceptable, making the deworming process less stressful for both the animal and the handler.
- Long-Lasting Protection: Provides effective control of parasites for several weeks, fitting easily into a seasonal rotational deworming schedule.
- Safe for Sensitive Groups: Can be used safely in pregnant mares and breeding stallions without affecting reproductive health.
- Improved Horse Health: Regular use leads to better nutrient absorption, improved coat condition, and reduced risk of parasite-induced colic.
IVE Race 4.8 Oral Paste Precautions
General Safety Guidelines
- Use IVE Race 4.8 Oral Paste only as directed by a veterinarian for effective parasite control in horses
- Do not exceed the recommended dose to avoid toxicity or adverse effects
- Ensure accurate weight measurement of the horse before dosing
- Follow proper deworming schedule for optimal results
Allergy and Sensitivity
- Avoid use in horses known to be hypersensitive to Ivermectin
- Monitor for signs of allergic reactions such as swelling, itching, or discomfort
Use in Special Populations
| Population | Precautions |
|---|---|
| Pregnant Mares | Use only if advised by a veterinarian |
| Lactating Mares | Use with caution; consult a veterinarian |
| Foals | Use only under veterinary supervision with proper dosage |
| Geriatric Horses | Monitor closely for sensitivity or adverse reactions |
Neurological Considerations
- Overdose may lead to neurological symptoms such as incoordination or lethargy
- Monitor for unusual behavior, tremors, or weakness after administration
Drug and Environmental Considerations
- Inform your veterinarian of any other medications or dewormers being used
- Avoid simultaneous use with other antiparasitic drugs unless prescribed
- Maintain proper hygiene in stables to prevent reinfestation
Administration and Storage Guidelines
- Administer IVE Race 4.8 Oral Paste orally as directed, ensuring full dose consumption
- Store in a cool, dry place away from direct sunlight
- Keep out of reach of children and other animals
- Do not use expired product
IVE Race 4.8 Oral Paste Usage
IVE Race 4.8 is a high-performance equine dewormer that requires precise administration based on the animal's weight. Proper usage ensures the complete elimination of parasites while maintaining the safety of the horse.
Administration Guidelines
| Feature | Details |
| Route of Administration | Oral (deposited at the back of the horse's tongue). |
| Dosing Mechanism | Adjustable "dial-a-dose" syringe calibrated by body weight. |
| Standard Dosage | 200 mcg of Ivermectin per kilogram of body weight. |
| Syringe Capacity | One full syringe typically treats a horse weighing up to 600 kg. |
| Frequency | As part of a strategic deworming program, usually every 8–12 weeks. |
Important Instructions
Determine Accurate Weight: Before administration, estimate the horse's weight using a weight tape or scale. Avoid under-dosing, as this can contribute to the development of parasite resistance.
Prepare the Syringe: Turn the knurled ring on the plunger to the left and slide it so the side nearest the barrel is at the prescribed weight marking. Turn the ring to the right to lock it in place.
Clear the Mouth: Ensure the horse’s mouth contains no food or hay before administration. This prevents the animal from spitting out the paste along with the feed.
Proper Positioning: Insert the syringe tip into the "interdental space" (the gap between the front and back teeth). Depress the plunger to deposit the paste on the back of the tongue.
Ensure Ingestion: Immediately raise the horse’s head for a few seconds after dosing to encourage swallowing. Observe the horse to ensure the full dose has been consumed.
IVE Race 4.8 Oral Paste Uses
IVE Race 4.8 is a comprehensive parasiticide used to treat and control a wide range of internal parasites that affect the health, coat quality, and athletic performance of horses.
Control of Large Strongyles: Highly effective against Strongylus vulgaris (adults and arterial larval stages), S. edentatus, and S. equinus.
Small Strongyle Management: Targets both adult and luminal larval stages of various small strongyle species, including those resistant to certain benzimidazole compounds.
Elimination of Pinworms: Treats and controls adult and fourth-stage larvae of Oxyuris equi, reducing tail-rubbing and irritation.
Ascarid (Roundworm) Treatment: Controls adult and third- and fourth-stage larvae of Parascaris equorum, which is particularly important for the health of growing foals.
Hairworm and Stomach Worm Control: Effectively eliminates Trichostrongylus axei (hairworms) and Habronema muscae (stomach worms).
Bot Infestation Treatment: Eradicates the oral and gastric stages of Gasterophilus spp. (bots), preventing gastric irritation and potential blockage.
Lungworm Control: Used to treat Dictyocaulus arnfieldi in both horses and donkeys.
Dermatological Support: Helps manage Summer Sores caused by Habronema and Draschia spp. cutaneous larvae, and dermatitis caused by neck threadworm (Onchocerca spp.) microfilariae.
IVE Race 4.8 Oral Paste Side Effects
General Side Effect Guidelines
- Side effects may vary depending on dosage, weight of the horse, and individual sensitivity
- Most horses tolerate IVE Race 4.8 Oral Paste well when used as directed
- Report any severe or unusual reactions to a veterinarian immediately
Common Side Effects
- Mild swelling or irritation at the mouth after administration
- Temporary loss of appetite
- Mild lethargy or reduced activity
Serious Side Effects
| Side Effect Category | Symptoms / Warning Signs |
|---|---|
| Neurological | Incoordination, tremors, कमजोरी, confusion-like behavior |
| Allergic Reactions | Swelling, itching, hives, breathing difficulty |
| Gastrointestinal | Diarrhea, colic, excessive salivation |
| General | Severe lethargy, unusual weakness |
Rare but Severe Side Effects
- Ivermectin toxicity due to overdose
- Severe neurological symptoms such as seizures or extreme incoordination
- Severe allergic reactions requiring immediate veterinary attention
Management and Monitoring
- Monitor the horse closely after administration for any behavioral or physical changes
- Ensure correct dosing based on body weight to avoid toxicity
- Seek immediate veterinary care if severe symptoms such as tremors, breathing difficulty, or collapse occur
- Maintain proper deworming schedule and follow veterinary guidance
IVE Race 4.8 Oral Paste FAQs
Q: What is IVE Race 4.8 used for in horses?
A: IVE Race 4.8 is a broad-spectrum dewormer containing Ivermectin. It is used to treat and control a wide variety of internal parasites, including large strongyles, small strongyles, pinworms, ascarids (roundworms), hairworms, large-mouth stomach worms, and bots.
Q: How do I determine the correct dose for my horse?
A: The syringe features a "dial-a-dose" plunger calibrated by body weight. You should estimate your horse's weight (using a weight tape if possible) and rotate the knurled ring on the plunger to the weight mark that most closely matches your horse's actual weight.
Q: Can I use this paste for foals or pregnant mares?
A: Yes, Ivermectin is generally considered safe for use in foals as young as 6 to 8 weeks of age. It has also been proven safe for use in pregnant mares and breeding stallions when administered at the recommended label dose.
Q: How often should I deworm my horse with IVE Race 4.8?
A: Frequency depends on your horse's age, pasture load, and local climate. Most veterinarians recommend a strategic deworming schedule based on fecal egg count (FEC) results. A common routine involves deworming every 8 to 12 weeks during the grazing season.
Q: Will this paste kill tapeworms?
A: No. Standard Ivermectin-only pastes like IVE Race 4.8 are not effective against tapeworms. If tapeworm control is necessary, you would typically need a combination product containing Praziquantel or a double dose of Pyrantel Pamoate as directed by a vet.
Q: What are the signs of a successful deworming treatment?
A: You may notice an improvement in the horse's coat quality, weight gain, and general energy levels over the following weeks. In horses with high parasite burdens, you might occasionally see dead worms passed in the manure shortly after treatment.
Q: Are there any side effects to watch for?
A: Most horses tolerate Ivermectin very well. However, in cases of extreme "Onchocerca" (neck threadworm) infestations, some horses may experience swelling or itching as the larvae die off. This is an immune reaction to the dying parasites, not the drug itself.
Q: How should I store the IVE Race syringe?
A: Store the syringe at room temperature (15–30°C). Avoid exposing the product to extreme heat or direct sunlight for extended periods, as this can degrade the active Ivermectin and affect the consistency of the paste.
Q: Can I use this product on other farm animals or pets?
A: No. This product is specifically formulated and concentrated for horses. Using equine-strength paste on smaller animals like dogs or cats can lead to severe toxicity or death, particularly in certain breeds (like Collies) that are hypersensitive to Ivermectin.
IVE Race 4.8 Oral Paste Interactions
General Drug Interaction Guidelines
- Always inform your veterinarian about all medications, supplements, or dewormers being used
- Avoid combining IVE Race 4.8 Oral Paste with other antiparasitic agents unless prescribed
- Do not administer alongside medications that affect the nervous system without veterinary advice
Drugs That May Interact with IVE Race 4.8 Oral Paste
| Drug / Drug Class | Interaction Effect |
|---|---|
| Other antiparasitic drugs | May increase risk of toxicity or adverse reactions |
| CNS-active drugs | May enhance neurological side effects such as sedation or incoordination |
| Macrocyclic lactones (e.g., Moxidectin) | Increased risk of overdose or toxicity |
| Sedatives or tranquilizers | May increase drowsiness or nervous system depression |
Feed and Environmental Interactions
- Ensure the horse consumes the full dose for effective parasite control
- Maintain proper feeding and hygiene practices to reduce reinfestation risk
- Avoid contamination of feed or water sources during administration
Monitoring During Interactions
- Monitor for signs of toxicity such as lethargy, tremors, or coordination issues
- Observe for reduced appetite or unusual behavior after administration
- Contact a veterinarian immediately if severe neurological or allergic symptoms occur
| Manufacturer | : | A. Menarini India Pvt Ltdine HCL) |
| Trade Name | : | DuraMectin |
| Generic Search | : | Ivermectin |
| Strength | : | 4.8MG |
Latest Products
