Boehringer Ingelheim Frontline Plus Tick & Flea Spot On for Dogs (Fipronil + (S)-Methoprene)
Frontline Plus Spot-On for Dogs by Boehringer Ingelheim is a trusted veterinary treatment specially formulated for dogs to provide long-lasting protection against fleas, ticks, and chewing lice. Containing two powerful active ingredients—Fipronil and (S)-Methoprene—this easy-to-apply topical solution offers dual-action protection by killing adult parasites and preventing the development of flea eggs and larvae.
For veterinary use only. Recommended for dogs and puppies 8 weeks of age and older.
Description
- Active Ingredients:
- Fipronil – 9.8%
- (S)-Methoprene – 8.8%
- Formulation: Topical Spot-On Solution
- Packaging: Available in pipettes according to dog weight categories
- Duration of Action: Protects for up to 30 days per application
Mechanism of Action:
Fipronil kills adult fleas and ticks by disrupting their central nervous system. (S)-Methoprene, an insect growth regulator, prevents flea eggs and larvae from maturing, effectively breaking the life cycle.
Precautions
Warnings:
- For external use only
- Do not use on cats or other animals
- Avoid contact with the pet’s eyes or mouth
- Keep treated animals away from children until the application site is dry
Who Should NOT Use It:
- Puppies younger than 8 weeks
- Dogs weighing less than the product’s labeled category
- Pregnant or lactating dogs (unless advised by a veterinarian)
- Dogs with known hypersensitivity to Fipronil or Methoprene
Uses:
Frontline Plus is indicated for the prevention and treatment of the following conditions in dogs:
- Flea infestations (Ctenocephalides spp.)
- Tick infestations (Rhipicephalus spp., Dermacentor spp., Ixodes spp.)
- Chewing lice
- Flea allergy dermatitis (FAD) (as part of a treatment strategy)
- Flea egg and larvae prevention for up to 8 weeks
Side Effects:
Frontline Plus is generally well-tolerated. However, possible side effects include:
- Mild temporary irritation at the application site
- Excessive salivation or licking
- Gastrointestinal signs such as vomiting or diarrhea (rare)
- Neurological symptoms (very rare and typically due to incorrect usage)
Severity: Most side effects are mild and self-limiting. In case of persistent symptoms or suspected allergic reaction, consult a veterinarian immediately.
FAQs:
Q1. How often should I apply Frontline Plus to my dog?
A: Apply once every 30 days for consistent protection.
Q2. Is Frontline Plus waterproof?
A: Yes, it remains effective even after bathing, swimming, or exposure to rain. Wait 24 hours after application before bathing your dog.
Q3. Can I use Frontline Plus on my cat?
A: No. This product is formulated for dogs only. Use the cat-specific version for feline use.
Q4. How quickly does it start working?
A: Frontline Plus begins killing fleas within 4 hours and ticks within 12 hours of application.
Q5. What should I do if I miss a dose?
A: Apply as soon as you remember and resume the monthly schedule.
Interactions
Frontline Plus has no known significant drug interactions. However, caution should be taken if your dog is undergoing treatment with other topical or systemic medications. Always consult your veterinarian before combining treatments.
Avoid using with other flea or tick control agents unless specifically directed.
| Manufacturer | : | Boehringer |
| Trade Name | : | |
| Generic Search | : | Fipronil + (S)-Methoprene |
| Strength | : | 2.68ml x 3 Pipette |








