Artisid Tablet (Indomethacin) | Used for Joint Pain and Arthritis Relief
Artisid Tablet (Indomethacin) is a potent non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, inflammation, and swelling associated with conditions such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout, and other musculoskeletal disorders. It works by inhibiting the production of prostaglandins, chemicals in the body responsible for pain and inflammation, providing effective relief from acute and chronic inflammatory conditions.
Product Overview
Artisid Tablet is a high-potency non-steroidal anti-inflammatory drug (NSAID) utilized for the management of moderate to severe pain and systemic inflammation. Containing Indomethacin, it is one of the most powerful inhibitors of prostaglandin synthesis available. This analgesic medication is particularly effective for treating intense joint pain, swelling, and stiffness associated with chronic inflammatory conditions, providing patients with improved mobility and symptom relief.
Product Composition
Indomethacin IP/BP: 50 mg (Active Ingredient)
Chemical Class: Indole acetic acid derivative
Excipients: Lactose, Magnesium Stearate, and Colloidal Silicon Dioxide
Formulation: Oral tablets/capsules designed for effective gastrointestinal absorption
Product Specification
| Feature | Details |
| Active Molecule | Indomethacin |
| Therapeutic Class | NSAID / Antipyretic / Analgesic |
| Available Strengths | 50 mg |
| Physical Form | Solid oral dosage form |
| Storage | Store in a cool, dry place; protect from direct sunlight |
Mechanism of Action
- Acts as a potent inhibitor of the cyclooxygenase (COX-1 and COX-2) enzymes, which are responsible for producing prostaglandins.
- By reducing prostaglandin levels, it effectively diminishes the chemical signals that cause pain, heat, and swelling in the tissues.
- Exerts a strong anti-inflammatory effect by inhibiting the motility of polymorphonuclear leukocytes (white blood cells) into the inflamed joints.
- Functions as an antipyretic, helping to reset the body's internal thermostat to reduce high fevers associated with inflammatory flares.
Key Benefits
- Superior Potency: Often more effective than standard over-the-counter NSAIDs for managing acute gouty arthritis and severe inflammation.
- Joint Mobility: Rapidly reduces morning stiffness and swelling, allowing patients with chronic conditions to maintain a more active lifestyle.
- Versatile Pain Relief: Highly effective against a wide range of conditions, from musculoskeletal disorders to severe menstrual pain.
- Proven Efficacy: Long-standing clinical history as a reliable first-line treatment for ankylosing spondylitis and rheumatoid disorders.
- Fast Recovery: Accelerates the healing process after minor surgical procedures or orthopedic injuries by controlling localized edema.
Precautions
| Condition or Situation | Precaution |
|---|---|
| Stomach ulcers | Use carefully as it may increase risk of bleeding or ulcers |
| Kidney disease | May worsen kidney function, monitor closely |
| Liver disease | Use cautiously as it may affect liver enzymes |
| Heart disease | May increase risk of cardiovascular events |
| Asthma | May trigger breathing difficulty in sensitive patients |
| Pregnancy | Avoid use especially in late pregnancy |
| Breastfeeding | Use only if clearly advised by doctor |
| Elderly patients | Higher risk of gastrointestinal and kidney side effects |
| Alcohol use | Avoid alcohol to reduce stomach bleeding risk |
| Other NSAIDs | Do not combine with other painkillers from the same class |
Important Safety Information
- Take Artisid Tablet exactly as prescribed
- Use after food to reduce stomach irritation
- Do not exceed recommended dose or duration
- Report symptoms like stomach pain, black stools, or vomiting blood immediately
- Stay hydrated during treatment
- Regular monitoring may be required for long-term use
Usage
Artisid Tablet is a high-strength anti-inflammatory treatment that must be used with precision to manage pain effectively while protecting the digestive system. Due to the high potency of Indomethacin, following the correct administration schedule is essential for achieving the best therapeutic results.
Administration Steps
Mealtime Strategy: Always take this NSAID pill with food, milk, or an antacid to minimize the risk of stomach upset or gastric irritation.
Fluid Intake: Swallow the tablet whole with a full glass of water; stay upright for at least 15 to 30 minutes after taking it to prevent esophageal irritation.
Consistency: Take the medication at the same times each day to maintain a steady level of the active ingredient in your joints and bloodstream.
Lowest Effective Dose: Use the smallest dose that provides relief for the shortest duration possible to reduce the potential for side effects.
Avoid Alcohol: Do not consume alcohol while on this Indomethacin therapy, as it can increase the risk of stomach bleeding.
Missed Dose: If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed one; never double the dosage.
Uses
Gout Management: Highly effective for the rapid relief of pain and inflammation during an acute gout attack.
Chronic Arthritis: Used to treat moderate to severe symptoms of rheumatoid arthritis and osteoarthritis, especially when other NSAIDs are insufficient.
Ankylosing Spondylitis: Provides targeted relief for inflammation of the spine and large joints, helping to maintain spinal flexibility.
Bursitis and Tendonitis: Reduces swelling and acute pain in the shoulders, elbows, or wrists caused by soft tissue inflammation.
Post-Operative Recovery: Utilized to manage pain and localized swelling following orthopedic surgeries or dental procedures.
Dysmenorrhea: Relieves severe menstrual cramps by lowering the prostaglandin levels in the uterine lining.
FAQs
Q: What is Artisid Tablet used for?
A: Artisid Tablet is used to relieve pain, inflammation, and swelling associated with rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gout, and other musculoskeletal and inflammatory conditions.
Q: How does Artisid Tablet work?
A: Artisid contains Indomethacin, an NSAID that works by blocking the enzyme cyclo-oxygenase (COX), which is responsible for the production of prostaglandins. By reducing prostaglandin levels, it helps relieve pain, reduce inflammation, and decrease swelling.
Q: How should I take Artisid Tablet?
A: Take Artisid Tablet exactly as prescribed by your doctor, usually with food, milk, or antacids to reduce the risk of stomach upset. Swallow the tablet whole with a glass of water and do not crush or chew it.
Q: What is the recommended dose of Artisid Tablet?
A: The dose of Artisid Tablet is determined by your doctor based on your condition and response to treatment. Always follow your doctor's prescribed dosage and do not exceed the recommended dose without medical guidance.
Q: What are the common side effects of Artisid Tablet?
A: Common side effects include nausea, stomach upset, heartburn, dizziness, and headache. Indomethacin may also cause more gastrointestinal side effects compared to other NSAIDs. Consult your doctor if any side effects persist or worsen.
Q: Can Artisid Tablet cause stomach ulcers or bleeding?
A: Yes. Like all NSAIDs, Indomethacin may increase the risk of stomach ulcers and gastrointestinal bleeding, particularly with long-term use or in patients with a history of peptic ulcers. Always take it with food and inform your doctor if you experience stomach pain or dark stools.
Q: Who should avoid taking Artisid Tablet?
A: Artisid Tablet should be avoided by patients with a history of peptic ulcers, gastrointestinal bleeding, severe kidney or liver disease, heart conditions, or those allergic to NSAIDs such as aspirin or ibuprofen.
Q: Can Artisid Tablet be taken with other medicines?
A: Indomethacin may interact with blood thinners, other NSAIDs, antihypertensives, diuretics, and certain heart medicines. Inform your doctor of all medicines, supplements, and herbal products you are taking before starting Artisid Tablet.
Q: Can pregnant or breastfeeding women take Artisid Tablet?
A: Artisid Tablet is not recommended during pregnancy, particularly in the third trimester, as it may cause serious harm to the unborn baby. Breastfeeding women should also consult their doctor before use as Indomethacin may pass into breast milk.
Q: What should I do if I miss a dose of Artisid Tablet?
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Interactions
| Interacting medicine or substance | Possible interaction effect |
|---|---|
| Other NSAIDs | May increase risk of stomach bleeding and ulcers |
| Blood thinners (anticoagulants) | Higher risk of bleeding complications |
| Corticosteroids | Increased risk of stomach irritation and ulcer |
| Antihypertensive medicines | May reduce blood pressure control effect |
| Diuretics | May increase risk of kidney problems |
| Lithium | May increase lithium levels and toxicity risk |
| Methotrexate | May increase risk of toxicity |
| SSRIs (antidepressants) | May increase risk of gastrointestinal bleeding |
| Alcohol | May increase stomach irritation and bleeding risk |
Important Interaction Advice
- Inform your healthcare provider about all medicines you use
- Avoid combining with other NSAID painkillers
- Limit or avoid alcohol during treatment
- Monitor for signs of stomach bleeding or unusual bruising
- Regular kidney and liver monitoring may be needed in long-term use
- Seek medical advice before starting new medicines during treatment
| Manufacturer | : | A. Menarini India Pvt Ltdine HCL) |
| Trade Name | : | Indocin |
| Generic Search | : | Indomethacin |
| Strength | : | 50mg |
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