Anovate Cream 20gm (Beclometasone 0.025% + Lidocaine 2.5% / Phenylephrine 0.10%) for fast relief of piles (hemorrhoids), and anal fissures
Anovate Cream 20gm is a triple-action topical formulation designed for the symptomatic management of anal and perianal problems such as hemorrhoids, anal fissures, itching, discomfort, irritation, and swelling. It contains Beclometasone (0.025%), Lidocaine (2.5%), and Phenylephrine (0.10%) to provide soothing relief and reduce swelling when applied as directed.
Product Overview
Anovate Rectal Cream is a specialized topical medication used for the treatment of hemorrhoids (piles) & anal fissures. It reduces the itching, discomfort, swelling, and pain associated with the condition. It combines an anti-inflammatory steroid (Beclometasone), a local anesthetic (Lidocaine), and a vasoconstrictor (Phenylephrine) to provide soothing relief and reduced swelling when applied as directed.
The active ingredients work together as follows:
- Beclometasone (0.025%) – A low-to-moderate potency corticosteroid that helps reduce inflammation, redness, and itching. It calms the immune response at the application site, making it effective for inflammatory irritation associated with hemorrhoidal flare-ups.
- Lidocaine (2.5%) – A local anesthetic that temporarily numbs the skin and mucous membranes, providing rapid relief from burning, itching, and pain during flare-ups.
- Phenylephrine (0.10%) – A vasoconstrictor that gently contracts dilated blood vessels in the anorectal region, which may help reduce swelling and support comfort. Constriction of superficial vessels can also lessen irritation during bowel movements.
Product Specification
| Feature | Details |
| Drug Classification | Anti-hemorrhoidal Topical Combination |
| Primary Indications | Internal/External Hemorrhoids, Anal Fissures, and Proctitis |
| Included Accessories | Detachable plastic applicator (nozzle) for internal rectal delivery |
| Mechanism Focus | Vasoconstriction, anesthetic nerve blockade, and anti-inflammatory action |
| Absorption Profile | Minimal systemic absorption when applied to intact mucous membranes |
Mechanism of Action
The clinical efficacy of Anovate Cream stems from the simultaneous, synergistic actions of its three active pharmaceutical ingredients:
- Anti-Inflammatory Action (Beclometasone): It diffuses across cell membranes to inhibit the release of arachidonic acid. This suppresses the synthesis of major inflammatory mediators like prostaglandins and leukotrienes, rapidly decreasing tissue edema, redness, and severe itching (pruritus).
- Nerve Blockade Pain Relief (Lidocaine): It temporarily binds to and blocks voltage-gated sodium channels along local nerve fibers. By preventing the influx of sodium ions, it arrests the initiation and conduction of nerve impulses, effectively numbing the area to intense burning and cutting pain.
- Vascular Decongestion (Phenylephrine): It directly stimulates alpha-1 adrenergic receptors on the smooth muscles of peripheral blood vessels in the anal canal. This causes localized vasoconstriction, narrowing dilated hemorrhoidal veins, shrinking swollen tissues, and lowering the risk of minor bleeding associated with bowel movements.
Key Benefits
- Rapid Pain Alleviation: Lidocaine provides near-instantaneous relief from acute pain, making sitting, walking, and defecation significantly more comfortable.
- Targeted Tissue Shrinkage: Phenylephrine directly addresses vascular engorgement, helping to shrink protruding external hemorrhoids.
- Reduces Pruritus and Irritation: Beclometasone effectively eliminates the distressing burning sensations and persistent itching that accompany healing anal tissues.
- Versatile Internal & External Design: Formulated to safely treat external skin irritations as well as deeper, internal conditions when paired with the enclosed applicator.
- Promotes Natural Healing: By controlling swelling, inflammation, and mechanical friction, it establishes an optimal microenvironment for tissue repair.
Precautions
Before using Anovate Cream, consult your healthcare provider if you:
Are allergic to beclometasone, lidocaine, phenylephrine, or related compounds
Have systemic infection or local skin infection in the application area
Have a history of sensitivity to corticosteroids or local anesthetics
Are pregnant, planning pregnancy, or breastfeeding
Are using other medications in the anorectal area
| Precaution | Description |
|---|---|
| External Use Only | Apply only to the affected external area; avoid internal use unless prescribed. |
| Eye Contact | Avoid contact with eyes, mouth, or broken skin. |
| Long-term Use | Prolonged use may cause skin thinning due to steroid content (Beclometasone). |
| Infections | Do not use on fungal, viral, or bacterial infections unless advised by a doctor. |
| Heart Conditions | Use carefully in patients with hypertension or heart disease (due to Phenylephrine). |
| Diabetes | Steroid component may affect blood sugar if used excessively. |
| Pregnancy & Breastfeeding | Use only if clearly recommended by a healthcare professional. |
Important Precautions:
Do not apply to broken or ulcerated skin without medical advice.
Avoid contact with eyes, lips, or other mucous membranes outside the treatment area.
Do not use for prolonged periods unless specifically directed, as long-term steroid use may cause local skin thinning.
Keep out of reach of children.
If you experience increased irritation, rash, blistering, or burning, discontinue use and seek medical advice.
Usage
Dosage and administration for this topical anorectal cream are designed to deliver targeted, localized relief while keeping systemic drug absorption as low as possible. Anovate Cream should be applied carefully following strict hygienic practices to avoid further tissue irritation.
| Aspect | Recommendation |
| Standard Application | Apply a small amount to the affected area 2 to 3 times daily, or as directed by a healthcare provider |
| Hygiene Protocol | Always wash and dry the anal area gently, and wash your hands thoroughly before and after every application |
| Internal Delivery | For internal conditions, attach the provided plastic applicator nozzle to the tube, insert gently, and squeeze slightly |
| Nozzle Maintenance | Clean the applicator nozzle thoroughly with warm water and soap after each internal use, then recap the tube |
| Treatment Duration | Limit continuous use to 7 days unless explicitly instructed otherwise by a physician to prevent skin thinning |
| Bowel Synchronization | When possible, apply the cream immediately after a bowel movement to maximize its local therapeutic contact time |
Uses
Internal and External Hemorrhoids: Prescribed to manage the pain, swelling, and vascular engorgement associated with both internal and protruding external piles.
Acute Anal Fissures: Utilized to numb severe cutting pain and reduce muscle spasms caused by small tears in the lining of the anal canal.
Proctitis Management: Helps soothe painful inflammation and irritation of the rectal mucous membrane lining.
Anal Pruritus Relief: Alleviates intense, distressing itching and burning sensations around the anorectal area caused by inflamed tissues.
Post-Operative Recovery: Used under medical supervision to relieve pain and local swelling following hemorrhoidectomy or other minor rectal surgeries.
Side Effects
Common Side Effects
- Mild burning or irritation at application site
- Itching or redness
- Temporary numbness
- Dryness of skin
- Mild discomfort
Less Common Side Effects
- Skin thinning (with prolonged use)
- Allergic skin reaction
- Increased sensitivity
- Headache (rare)
- Mild swelling
Serious Side Effects
| Serious Side Effect | Description |
|---|---|
| Severe skin thinning | Fragile skin or easy bruising with long-term use. |
| Allergic reaction | Rash, swelling, or severe irritation. |
| Systemic steroid effects | Rare with overuse: hormonal imbalance or weakness. |
| Blood pressure changes | Possible increase in BP due to phenylephrine (rare). |
Important Points
- Most side effects are mild and temporary.
- Avoid long-term or excessive use.
- Seek medical advice if irritation worsens or symptoms persist.
FAQs
Q: What is Anovate Cream?
A: Anovate Cream is a combination topical medication containing Beclometasone 0.025%, Lidocaine 2.5%, and Phenylephrine 0.10%. It is used to relieve the symptoms of hemorrhoids and other anorectal conditions by combining anti-inflammatory, local anesthetic, and decongestant actions in one cream.
Q: What is the product used for?
A: Anovate Cream is used to relieve pain, itching, swelling, and discomfort associated with hemorrhoids (piles), anal fissures, pruritus ani, and other inflammatory conditions of the anal and rectal area.
Q: How does it work?
A: Beclometasone is a corticosteroid that reduces inflammation and swelling. Lidocaine is a local anesthetic that numbs the affected area to relieve pain and itching. Phenylephrine is a decongestant that constricts blood vessels, helping to reduce swelling and bleeding associated with hemorrhoids.
Q: How is it applied?
A: Apply a small amount of cream to the affected area using a clean finger or the applicator provided. It can be applied externally around the anal area or inserted gently into the rectum as directed by the doctor. Wash hands thoroughly before and after application.
Q: How often should it be applied?
A: It is usually applied 2 to 3 times daily and after each bowel movement, or as directed by the doctor. Do not apply more than the recommended amount or frequency.
Q: How long should it be used?
A: Anovate Cream is intended for short-term use only, typically not more than 7 days. Prolonged use of corticosteroid-containing creams can cause skin thinning and other side effects. Always follow the doctor's instructions regarding duration of use.
Q: Who should not use it?
A: People with a known allergy to Beclometasone, Lidocaine, or Phenylephrine should not use this cream. It should also be avoided in patients with fungal, viral, or bacterial infections of the anal area, and in those with certain heart conditions or uncontrolled high blood pressure.
Q: What are the common side effects?
A: Common side effects include mild burning, stinging, or itching at the site of application. Prolonged use may cause skin thinning, stretch marks, or increased sensitivity in the treated area. If any severe reaction occurs, discontinue use and consult a doctor.
Q: Is it safe during pregnancy or breastfeeding?
A: Anovate Cream should be used with caution during pregnancy and breastfeeding. It should only be used if the benefit outweighs the risk and strictly under medical supervision. Consult your doctor before use.
Q: Can it be used in children?
A: Anovate Cream is generally not recommended for use in children without medical supervision. The use of corticosteroid-containing products in children requires careful consideration and doctor guidance.
Q: Can it be used for long periods?
A: No, prolonged use is not recommended as the corticosteroid component Beclometasone can cause skin thinning, hormonal effects, and increased risk of local infections with extended use. Use only for the duration prescribed by the doctor.
Interactions
| Drug / Group | Effect with Anovate Cream (Beclometasone + Lidocaine + Phenylephrine) |
|---|---|
| Other topical steroids | May increase risk of skin thinning and irritation. |
| Other local anesthetics | Can increase numbness or local side effects. |
| Blood pressure medicines | Phenylephrine may reduce effectiveness or affect BP control. |
| MAO inhibitors | May increase effects of phenylephrine (BP-related risks). |
| Beta-blockers | May interact with phenylephrine and affect heart rate/BP. |
| Other rectal creams/ointments | May increase irritation or reduce effectiveness if overused. |
- Though applied topically, ingredients may interact in certain cases:
- Other topical steroids – increased risk of skin thinning
- Blood pressure medications or MAO inhibitors – caution with Phenylephrine use
- Lidocaine-containing products – additive anesthetic effects
- Beta-blockers – may affect blood pressure when used with Phenylephrine
| Manufacturer | : | USV Pharma, India |
| Trade Name | : | |
| Generic Search | : | Beclomethasone Dipropionate Phenylephrine Lignocaine |
| Strength | : | 20 gm |
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