Xtrant Capsule ( Estramustine )
Xtrant Capsule (Estramustine) is a prescription medication used primarily to treat prostate cancer. It combines estrogen and nitrogen mustard to inhibit cancer cell growth. Xtrant helps slow disease progression and relieve symptoms, offering an effective hormone-based chemotherapy option for advanced prostate cancer patients.
Xtrant Capsule contains Estramustine Phosphate 140 mg, a chemotherapy medication used in the management of progressive or metastatic prostate cancer. It combines estrogen and nitrogen mustard components to inhibit cancer cell growth and proliferation. This prescription-only medicine is intended for use under the supervision of an oncologist.​
Precautions of Xtrant Capsule:
Before using Xtrant, inform your doctor if you:
- Have a history of blood clots, stroke, or cardiovascular disease​
- Suffer from liver or kidney disorders​
- Experience migraines, seizures, or high blood pressure​
- Have diabetes or electrolyte imbalances
Uses of Xtrant Capsule:
Xtrant is indicated for:​
- Advanced Prostate Cancer: Particularly in cases where the cancer has spread beyond the prostate gland.​
- Hormone-Refractory Prostate Cancer: When the disease no longer responds to standard hormone therapies.​
It may also be used in combination with other chemotherapy agents as part of a comprehensive cancer treatment plan.
Side Effect of Xtrant Capsule:
Common side effects may include:​
- Nausea and vomiting​
- Diarrhea​
- Breast tenderness or enlargement​
- Leg cramps​
- Fatigue​
- Insomnia​
- Impotence​
Serious side effects requiring immediate medical attention:​
- Allergic reactions (e.g., swelling of face, lips, or throat)​
- Shortness of breath or chest pain​
- Sudden severe headaches or vision changes​
- Signs of blood clots (e.g., leg swelling, redness)​
Consult your healthcare provider if you experience any adverse effects.
FAQs of Xtrant Capsule:
1. How long does it take for Xtrant to show results?
It may take up to 3 months to observe the therapeutic effects. Regular follow-ups with your doctor are essential to monitor progress.​
2. Can I consume dairy products while on Xtrant?
Avoid dairy products around the time of taking Xtrant, as calcium can interfere with its absorption.​
3. What should I do if I miss a dose?
Take the missed dose as soon as you remember. If it's close to your next scheduled dose, skip the missed one. Do not double the dose.​
4. Is Xtrant safe for women?
No, Xtrant is intended for use in men only and is contraindicated in women, especially during pregnancy.
Interactions of Xtrant Capsule:
Xtrant may interact with:​
- Antacids or supplements containing calcium, magnesium, or aluminum​
- Tricyclic antidepressants​
- ACE inhibitors used for hypertension or heart conditions​
Maintain a 2-hour gap between Xtrant and any calcium-containing products. Always inform your doctor about all medications and supplements you are taking.
| Manufacturer | : | Natco Pharma, India |
| Trade Name | : | |
| Generic Search | : | Estramustine |
| Strength | : | 140MG |








