Methotrex Tablets (Methotrexate)
Methotrex Tablets contain Methotrexate, a disease-modifying antirheumatic drug (DMARD) that slows down the growth of certain cells, including immune system cells. It is commonly used to treat cancer, autoimmune diseases, and severe psoriasis by reducing abnormal cell growth and controlling inflammation.
Introduction of Methotrex Tablets (Methotrexate)
Methotrex Tablets contain Methotrexate, a potent antimetabolite and immunosuppressant drug widely used in modern medicine for its ability to regulate abnormal cell growth and modulate the immune system. Methotrexate works by inhibiting the enzyme dihydrofolate reductase, which is essential for DNA synthesis and cell replication. By doing so, it slows down the rapid division of cells in certain conditions, making it effective for both oncology (cancer treatment) and autoimmune disorders.
In oncology, Methotrex Tablets are prescribed to manage leukemia, lymphoma, breast cancer, osteosarcoma, and other malignancies, helping to reduce tumor growth and improve patient outcomes. In autoimmune conditions, such as rheumatoid arthritis, psoriasis, and lupus, Methotrex Tablets act as a disease-modifying antirheumatic drug (DMARD), reducing inflammation, joint damage, and disease progression.
Precautions of Methotrex Tablets (Methotrexate)
- Avoid if allergic to Methotrexate.
- Do not use during pregnancy (can harm the fetus).
- Use caution while breastfeeding.
- Inform doctor if you have liver, kidney, or blood disorders.
- Avoid alcohol during treatment.
- Do not adjust dose without doctor approval.
- Monitor for infections, unusual bruising, or bleeding.
- Store in a cool, dry place away from children.
Uses of Methotrex Tablets
- Rheumatoid arthritis – Reduces inflammation and joint damage.
- Psoriasis – Controls severe plaque psoriasis.
- Cancer treatment – Used for leukemia, lymphoma, breast cancer, and other cancers.
- Autoimmune diseases – Manages conditions like Crohn’s disease and lupus.
- Ectopic pregnancy – Can be used to stop abnormal cell growth.
Side Effects of Methotrex Tablets (Methotrexate)
- Nausea and vomiting
- Diarrhea or upset stomach
- Mouth sores or ulcers
- Fatigue or tiredness
- Hair thinning or hair loss
- Skin rash or itching
- Liver damage (yellow eyes/skin, dark urine)
- Low blood counts (easy bruising, infections)
- Shortness of breath or persistent cough
- Severe allergic reactions (swelling, difficulty breathing)
FAQs of Methotrex Tablets
1. What is Methotrex Tablets used for?
Treats cancer, rheumatoid arthritis, severe psoriasis, autoimmune diseases, and ectopic pregnancy.
2. How should I take Methotrex Tablets?
Take exactly as prescribed, usually once weekly for autoimmune conditions. Dose varies for cancer treatment.
3. Can I take Methotrex Tablets with other medicines?
Only under doctor supervision; many drugs can interact, including NSAIDs, antibiotics, and liver-toxic medications.
4. Is Methotrex Tablets safe during pregnancy?
No, it is highly teratogenic; avoid unless specifically prescribed for ectopic pregnancy under medical supervision.
5. What are common side effects?
Nausea, vomiting, diarrhea, mouth sores, fatigue, and mild hair loss.
Interactions of Methotrex Tablets
- Avoid combining with NSAIDs without doctor guidance.
- Interacts with antibiotics like penicillin or sulfonamides.
- May interact with liver-toxic drugs (hepatotoxicity risk).
- Caution with blood thinners (warfarin, heparin).
- Avoid live vaccines while on Methotrexate.
- Alcohol may increaseolic acid).
- Always disclose all medicines and herbal products.
| Manufacturer | : | Healing Pharma |
| Trade Name | : | Folitrax |
| Generic Search | : | Methotrexate |
| Strength | : | 2.5mg, 5mg |
Certified Content
Dr. Priya Nair
Clinical Pharmacist & Senior Drug Information Specialist | 9 years
Pharm.D. (Doctor of Pharmacy)
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