Clotan (Tolfenamic Acid) | Used for Pain Relief and Migraine Treatment
Clotan Tolfenamic Acid Tablets are a powerful nonsteroidal anti-inflammatory drug (NSAID) designed to provide effective relief from pain and inflammation. The active ingredient, Tolfenamic Acid, works by inhibiting enzymes responsible for causing inflammation and pain in the body.
Product Overview
Clotan is a potent non-steroidal anti-inflammatory drug (NSAID) specifically engineered for the effective management of acute pain and inflammatory conditions. Containing Tolfenamic Acid, it belongs to the fenamate group and is highly regarded for its rapid absorption and dual-action approach to pain relief. By targeting the underlying chemical triggers of discomfort, Clotan provides significant relief for patients suffering from migraine attacks, musculoskeletal injuries, and post-operative pain.
Product Composition
- Tolfenamic Acid BP: 200 mg (Active Ingredient)
- Chemical Class: Anthranilic acid derivative (Fenamate)
- Excipients: Microcrystalline Cellulose, Maize Starch, and Magnesium Stearate
- Formulation: Oral tablets designed for rapid systemic distribution
Product Specification
| Feature | Details |
| Brand Name | Clotan |
| Active Molecule | Tolfenamic Acid |
| Therapeutic Class | NSAID / Analgesic / Antipyretic |
| Dosage Strength | 200 mg |
| Onset of Action | Rapid (Peak plasma levels within 60-90 mins) |
Mechanism of Action
- Inhibits the cyclooxygenase (COX) enzymes, which effectively stops the biosynthesis of prostaglandins, the primary mediators of pain and swelling.
- Uniquely acts as a prostaglandin receptor antagonist, providing an extra layer of relief by blocking the action of prostaglandins already present in the tissues.
- Reduces neuronal inflammation in the cranial blood vessels, which is a key factor in the pathology of severe migraine headaches.
- Exerts an antipyretic effect by acting on the heat-regulating center of the hypothalamus to reduce fever.
Key Benefits
- Targeted Migraine Relief: Specifically clinically proven to reduce the intensity and duration of acute migraine symptoms, including sensitivity to light and sound.
- Rapid Pain Suppression: The fast-acting formula ensures quick recovery from acute pain associated with dental work or sports injuries.
- Anti-Inflammatory Power: Effectively reduces stiffness and swelling in conditions like rheumatoid arthritis and osteoarthritis.
- Dysmenorrhea Management: Provides superior relief from painful menstrual cramps by lowering uterine prostaglandin levels.
- Versatile Analgesic: Serves as a reliable multi-purpose painkiller for various inflammatory disorders without the heavy sedative effects of opioids.
Precautions
| Condition or Situation | Precaution |
|---|---|
| Stomach ulcers | Use cautiously as it may increase risk of stomach bleeding |
| Kidney disease | Monitor kidney function during treatment |
| Liver disease | Use carefully in patients with liver impairment |
| Heart disease | May increase cardiovascular risk in susceptible patients |
| Asthma | Use cautiously as NSAIDs may trigger breathing problems |
| Pregnancy | Avoid use especially during late pregnancy |
| Breastfeeding | Use only if advised by a healthcare professional |
| Elderly patients | Higher risk of stomach and kidney side effects |
| Alcohol use | Avoid alcohol to reduce stomach irritation risk |
| Other painkillers | Avoid combining with other NSAID medicines |
Important Safety Information
- Take Clotan exactly as prescribed
- Use after food to reduce stomach irritation
- Do not exceed the recommended dose or duration
- Report symptoms like stomach pain, black stools, or breathing difficulty immediately
- Stay hydrated during treatment
- Regular monitoring may be required during long-term use
Usage
Clotan is a high-potency analgesic treatment used to manage acute flares of pain and inflammation. To maximize the efficacy of Tolfenamic Acid and ensure a fast recovery, it is important to adhere to the recommended timing, especially when treating the early onset of symptoms.
Administration Steps
Timely Intake: For migraine relief, take the tablet at the very first sign of an aura or headache for the most effective pain suppression.
Gastric Protection: Always swallow this NSAID tablet with a full glass of water during or immediately after a meal to prevent stomach irritation.
Whole Tablet: Do not crush or chew the tablet; it should be swallowed whole to maintain the intended absorption rate.
Hydration: Maintain good hydration throughout the day while taking this anti-inflammatory medicine to support kidney function.
Duration of Use: For acute conditions, limit use to the shortest period necessary; consult a doctor for long-term chronic pain management.
Uses
Migraine Management: Specifically indicated for the treatment of acute migraine attacks, effectively reducing throbbing pain and nausea.
Primary Dysmenorrhea: Provides rapid relief from painful menstrual cramps and associated discomfort.
Rheumatoid & Osteoarthritis: Used to reduce joint pain, swelling, and morning stiffness in patients with degenerative joint diseases.
Dental Pain: Effectively manages inflammation and soreness following dental surgery or tooth extractions.
Soft Tissue Injuries: Ideal for treating acute musculoskeletal pain resulting from strains, sprains, or sports-related injuries.
Fever Reduction: Acts as a reliable antipyretic to lower high body temperature during inflammatory episodes.
FAQs
Q: What is Clotan Tablet used for?
A: Clotan Tablet is used for the acute treatment of migraine attacks. It helps relieve migraine pain and associated symptoms such as nausea, vomiting, and sensitivity to light and sound.
Q: How does Clotan Tablet work?
A: Clotan contains Tolfenamic Acid, an NSAID that works by blocking the production of prostaglandins, chemicals in the body responsible for pain, inflammation, and the widening of blood vessels that contribute to migraine headaches.
Q: How should I take Clotan Tablet?
A: Take Clotan Tablet at the onset of a migraine attack as directed by your doctor. It is usually taken with a glass of water and can be taken with food to reduce the risk of stomach upset.
Q: How quickly does Clotan Tablet work?
A: Clotan Tablet typically starts working within 30 to 60 minutes of administration, providing effective relief from migraine pain and associated symptoms.
Q: Can I take a second dose of Clotan Tablet if my migraine does not improve?
A: If your migraine does not improve after the first dose, a second dose may be taken after 1 to 2 hours as advised by your doctor. Do not exceed the recommended daily dose without medical guidance.
Q: What are the common side effects of Clotan Tablet?
A: Common side effects include nausea, stomach discomfort, diarrhoea, and dizziness. Some patients may also experience a mild tingling or warm sensation. Consult your doctor if side effects persist or worsen.
Q: Can Clotan Tablet be used for everyday headaches or pain?
A: No. Clotan Tablet is specifically indicated for the acute treatment of migraine attacks and is not intended for the treatment of everyday headaches or other types of pain unless directed by your doctor.
Q: Who should avoid taking Clotan Tablet?
A: Clotan Tablet should be avoided by patients with a history of peptic ulcers, gastrointestinal bleeding, kidney or liver disease, heart conditions, or those allergic to NSAIDs such as aspirin or ibuprofen. Always inform your doctor of your full medical history.
Q: Can pregnant or breastfeeding women take Clotan Tablet?
A: Clotan Tablet is not recommended during pregnancy, particularly in the third trimester, as it may harm the unborn baby. Breastfeeding women should also consult their doctor before use.
Q: Can Clotan Tablet interact with other medicines?
A: Yes. Clotan may interact with blood thinners, other NSAIDs, antihypertensives, and certain heart medicines. Inform your doctor of all medicines, supplements, and herbal products you are taking before starting Clotan Tablet.
Interactions
| Interacting medicine or substance | Possible interaction effect |
|---|---|
| Other NSAIDs | May increase risk of stomach bleeding and ulcers |
| Anticoagulants (blood thinners) | Higher risk of bleeding complications |
| Corticosteroids | May increase stomach irritation and ulcer risk |
| Antihypertensive medicines | May reduce blood pressure lowering effect |
| Diuretics | May increase risk of kidney problems |
| Lithium | May increase lithium levels and toxicity risk |
| Methotrexate | May increase toxicity of methotrexate |
| Alcohol | May worsen stomach irritation and bleeding risk |
| Antidepressants (SSRIs) | May increase risk of gastrointestinal bleeding |
Important Interaction Advice
- Inform your healthcare provider about all medicines you use
- Avoid combining with other painkillers unless advised
- Limit alcohol intake during treatment
- Monitor for signs of stomach bleeding or severe abdominal pain
- Regular kidney and liver monitoring may be needed during prolonged use
- Seek medical advice if unusual bruising or bleeding occurs
| Manufacturer | : | A. Menarini India Pvt Ltdine HCL) |
| Trade Name | : | |
| Generic Search | : | Tolfenamic Acid |
| Strength | : | 200mg. |
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