Bracanat 150mg Capsule (Olaparib)
Bracanat 150mg Capsule contains Olaparib, a targeted anti-cancer medicine used to treat ovarian, breast, pancreatic, and prostate cancers with BRCA mutations. It works by preventing cancer cells from repairing their DNA.
Introduction of Bracanat 150mg Capsule (Olaparib)
Bracanat 150mg Capsule contains Olaparib, a targeted therapy belonging to a class of medicines known as PARP (poly ADP-ribose polymerase) inhibitors. It is used for the treatment of certain types of cancers, including ovarian, breast, pancreatic, and prostate cancers, particularly in patients with BRCA1 or BRCA2 gene mutations. Olaparib works by blocking the PARP enzyme, which cancer cells rely on to repair damaged DNA. By inhibiting this repair mechanism, the medicine causes cancer cells to accumulate damage and eventually die, while having a more selective effect on cancer cells compared to traditional chemotherapy.
Precautions of Bracanat 150mg Capsule (Olaparib)
- Use only under oncologist supervision
- Not recommended during pregnancy or breastfeeding
- Effective contraception required during and after treatment
- Regular blood tests needed to monitor blood counts
- Inform doctor about kidney or liver problems
- Avoid grapefruit or grapefruit juice
- Do not crush or chew capsules
Uses of Bracanat 150mg Capsule (Olaparib)
- Ovarian cancer (maintenance therapy and recurrent cases)
- Breast cancer (HER2-negative with BRCA mutation)
- Pancreatic cancer (BRCA-mutated cases)
- Prostate cancer (metastatic, BRCA-mutated)
- Maintenance therapy after response to platinum-based chemotherapy
Side Effects of Bracanat 150mg Capsule (Olaparib)
Common side effects:
- Nausea and vomiting
- Fatigue or weakness
- Anemia (low red blood cells)
- Loss of appetite
- Diarrhea
- Headache
Serious side effects:
- Severe anemia or low blood counts
- Risk of infections
- Pneumonitis (lung inflammation)
- Secondary cancers (rare, e.g., leukemia)
- Blood clots
FAQs of Bracanat 150mg Capsule (Olaparib)
Q1. What is Bracanat Capsule used for?
It is used to treat certain cancers with BRCA gene mutations, including ovarian, breast, pancreatic, and prostate cancers.
Q2. How does Olaparib work?
It blocks the PARP enzyme, preventing cancer cells from repairing DNA, leading to their death.
Q3. How should I take Bracanat Capsule?
Take it exactly as prescribed by your doctor, usually twice daily, with or without food.
Q4. Can it be used during pregnancy?
No, it may harm the unborn baby. Avoid pregnancy during treatment.
Q5. Do I need regular monitoring?
Yes, regular blood tests are required to monitor for side effects.
Interactions of Bracanat 150mg Capsule (Olaparib)
Bracanat Capsule may interact with:
- Strong CYP3A inhibitors (e.g., ketoconazole, clarithromycin)
- CYP3A inducers (e.g., rifampicin, phenytoin)
- Other anti-cancer drugs
- Grapefruit products (may increase drug levels)
- Certain antifungal and antiviral medicines
| Manufacturer | : | Natco Pharma, India |
| Trade Name | : | Lynparza |
| Generic Search | : | Olaparib |
| Strength | : | 150mg |









