Zoetis Simparica Tick and Flea Control Tablet for Dogs (Sarolaner)
Simparica (Sarolaner) by Zoetis is a fast-acting, chewable oral tablet formulated for dogs to protect them against fleas, ticks, and mites. Designed for pet owners and veterinarians seeking reliable monthly parasite protection, Simparica is safe for dogs over 8 weeks of age and weighing at least 1.3 kg.
Description:
Simparica contains Sarolaner, an isoxazoline-class ectoparasiticide. It works by inhibiting the function of nerve receptors in parasites, leading to their rapid death. Each chewable tablet is beef-flavored, ensuring easy administration. Simparica starts killing fleas within 3 hours and ticks within 8 hours of administration.
Packaging options available based on dog weight:
- 10.1–20.0 kg
- 20.1–40.0 kg
Precautions:
- Not for human use.
- Do not use in cats or other animals not specified on the label.
- Use only in dogs aged 8 weeks and older, and weighing at least 1.3 kg.
- Use with caution in dogs with a history of neurological disorders, including seizures.
- Pregnant, breeding, or lactating dogs: Safety has not been evaluated.
- Always consult a veterinarian before starting or stopping treatment.
Uses:
Simparica is indicated for the treatment and prevention of:
- Flea infestations (Ctenocephalides felis)
Tick infestations, including:
- Brown dog tick (Rhipicephalus sanguineus)
- Lone star tick (Amblyomma americanum)
- Gulf Coast tick (Amblyomma maculatum)
- American dog tick (Dermacentor variabilis)
- Deer tick/Black-legged tick (Ixodes scapularis)
Mite infestations, such as:
- Demodex spp.
- Sarcoptes scabiei
- Otodectes cynotis (ear mites)
The product provides persistent efficacy for a full month following administration.
Side Effects:
Most dogs tolerate Simparica well. However, like all medications, it may cause side effects in some animals:
Common side effects:
- Vomiting
- Diarrhea
- Lethargy
- Anorexia (loss of appetite)
- Tremors (rare)
Severity:
Side effects are generally mild to moderate and transient. In rare cases, neurological reactions such as tremors, ataxia, or seizures have been reported, particularly in dogs with a history of seizures.
If adverse effects occur, contact a veterinarian immediately.
FAQs:
Q1: How long does Simparica take to work?
A: Starts killing fleas within 3 hours and ticks within 8 hours after administration.
Q2: Is Simparica safe for puppies?
A: Yes, for puppies 8 weeks and older, weighing at least 1.3 kg.
Q3: Can Simparica be given with food?
A: Yes, but it can be administered with or without food.
Q4: What if I miss a dose?
A: Administer as soon as you remember and resume monthly dosing. Avoid giving two doses at once.
Q5: Can Simparica prevent heartworms?
A: No. Simparica does not protect against heartworm. A separate preventive is required.
Interactions:
Sarolaner may interact with other isoxazoline-class drugs or medications affecting the central nervous system.
Inform your veterinarian if your dog is currently on:
- Seizure medications (e.g., phenobarbital)
- Other antiparasitic drugs
- Steroids or immunosuppressants
No known adverse interactions with vaccines, antibiotics, or NSAIDs under normal veterinary supervision.
| Manufacturer | : | Zoetis |
| Trade Name | : | |
| Generic Search | : | Sarolaner |
| Strength | : |








