Topgraf 0.1% Ointment (Tacrolimus 0.1%)
Topgraf 0.1% Ointment contains Tacrolimus, an immunosuppressive medication used topically to treat moderate to severe eczema (atopic dermatitis) in patients who have not responded well to conventional treatments.
Introduction
Topgraf 0.1% Ointment contains Tacrolimus, a potent immunomodulatory agent used topically to treat moderate to severe atopic dermatitis (eczema). It is designed for adults and children over 16 years who are unresponsive or intolerant to conventional topical corticosteroids. It offers an effective non-steroidal alternative for long-term eczema management.
Precautions
- Avoid prolonged exposure to sunlight or UV lamps while using this product.
- Not recommended during active skin infections (bacterial, viral, or fungal) without proper treatment.
- Avoid in children under 16 years unless prescribed.
- Use with caution in immunocompromised individuals.
- Do not use if allergic to Tacrolimus or other macrolide immunosuppressants.
Uses
Topgraf 0.1% Ointment is primarily used to treat:
- Atopic dermatitis (eczema) in moderate to severe cases
- Inflammatory skin conditions where corticosteroid use is not suitable
- Long-term maintenance to prevent flare-ups
Side Effects
While generally well tolerated, some users may experience:
- Common: Burning, stinging, itching, or redness at the application site (usually subsides within a few days)
- Less Common: Skin acne, herpes simplex (cold sores), flu-like symptoms
- Rare but Serious: Signs of infection or skin sensitivity to sunlight
- Severity: Most side effects are mild and temporary. Persistent or worsening symptoms should be reported to a healthcare provider.
FAQs
Q1. Can I use Topgraf 0.1% on my face?
Yes, it is commonly used on facial areas where corticosteroids may cause thinning. Apply as directed.
Q2. How long does it take to work?
Improvement is usually seen within a few days to a week. Continuous improvement may occur with ongoing use.
Q3. Can I apply moisturizer along with it?
Yes, but leave a gap of at least 2 hours between applying the ointment and your moisturizer.
Q4. Is it a steroid?
No, Tacrolimus is a non-steroidal immunosuppressant.
Q5. Can I stop using it once symptoms improve?
Yes, but consult your doctor before stopping. In some cases, intermittent long-term use is recommended to prevent flare-ups.
Interactions
- Topical interactions are rare, but avoid using other medicated creams/ointments at the same site unless prescribed.
- Avoid concurrent systemic immunosuppressants or therapies that increase sun sensitivity.
- Consult your doctor if taking strong CYP3A4 inhibitors (like erythromycin or ketoconazole) as they may increase Tacrolimus absorption.
| Manufacturer | : | |
| Trade Name | : | Protopic |
| Generic Search | : | |
| Strength | : | 10 mg |








