Sacubrook-V Tablets (Sacubitril + Valsaratan)
Sacubrook-V Tablets (Sacubitril + Valsartan) are a combination medication used in adults to manage chronic heart failure with reduced ejection fraction (HFrEF), helping reduce hospitalizations and improve survival.
Introduction
Sacubrook-V Tablets combine Sacubitril and Valsartan, two active ingredients used together to manage certain heart conditions.
This medicine is prescribed for adults with chronic heart failure with reduced ejection fraction (HFrEF). By relaxing blood vessels, reducing fluid retention, and lowering strain on the heart, Sacubrook-V helps improve heart function and quality of life.
It is only available with a doctor’s prescription and should be used under medical supervision.
Precautions
- Do not take if you are allergic to Sacubitril, Valsartan, or similar medicines.
- Avoid use during pregnancy and breastfeeding – it may harm the unborn baby.
- Not recommended in patients with:
- Severe liver problems
- History of angioedema (swelling due to ACE inhibitors/ARBs)
- Severe kidney impairment
- Regular blood pressure and kidney function monitoring is required.
Uses
Sacubrook-V Tablets are commonly prescribed for:
- Heart failure with reduced ejection fraction (HFrEF)
- Reducing the risk of hospitalization due to heart failure
- Improving survival in patients with chronic heart failure
Side Effects
Like all medicines, Sacubrook-V may cause side effects. Most are mild, but some can be serious.
Common side effects:
- Low blood pressure (hypotension)
- Dizziness or fainting
- Increased potassium levels (hyperkalemia)
- Fatigue
Serious side effects (seek medical help immediately):
- Swelling of the face, lips, tongue, or throat (angioedema)
- Severe dizziness or fainting
- Kidney function impairment
FAQs
Q1: What is Sacubrook-V used for?
Sacubrook-V is used to treat chronic heart failure with reduced ejection fraction, reducing hospitalizations and improving survival.
Q2: How should I take Sacubrook-V Tablets?
Take exactly as prescribed by your doctor, usually twice daily, with or without food.
Q3: Can I take Sacubrook-V with ACE inhibitors?
No. It should not be taken with ACE inhibitors due to risk of severe side effects. A 36-hour gap is required if switching from an ACE inhibitor to Sacubrook-V.
Q4: Is Sacubrook-V safe during pregnancy?
No. Sacubrook-V can harm the unborn baby. It should not be taken during pregnancy or breastfeeding.
Q5: What should I do if I miss a dose?
Take it as soon as you remember. If it’s close to the next dose, skip the missed dose. Do not double dose.
Interactions
Sacubrook-V may interact with:
- ACE inhibitors (e.g., Enalapril, Lisinopril) – should not be used together
- Potassium supplements or potassium-sparing diuretics – may increase potassium levels
- NSAIDs (e.g., Ibuprofen, Naproxen) – may reduce kidney function
- Lithium – risk of lithium toxicity increases
- Other blood pressure medications – additive hypotensive effect
Always inform your doctor about all medications and supplements you are taking.
| Manufacturer | : | Healing Pharma |
| Trade Name | : | |
| Generic Search | : | Sacubitril and Valsartan |
| Strength | : | 24mg+26mg & 49mg+51mg & 12mg+13mg |








