Regonat Tablet (Regorafenib)
Regonat Tablet (Regorafenib) is an oral cancer medication used to treat advanced colorectal cancer, gastrointestinal stromal tumors (GIST), and hepatocellular carcinoma (liver cancer) when other treatments have failed.
Introduction
Regonat Tablet contains Regorafenib, a targeted oral anticancer medication classified as a multi-kinase inhibitor. It is designed for adults who have been previously treated for certain advanced cancers and have not responded to other therapies. This medication is specifically used in the treatment of colorectal cancer, gastrointestinal stromal tumors (GIST), and hepatocellular carcinoma (liver cancer).
Regonat is prescribed under strict medical supervision and is meant for use only when prescribed by an oncologist or healthcare provider experienced in cancer treatment.
Precautions of Regonat Tablet (Regorafenib)
Before taking Regonat, tell your doctor if you:
- Have liver problems
- Have bleeding disorders
- Have high blood pressure
- Are pregnant or breastfeeding
- Are taking any other medications or supplements
Uses of Regonat Tablet (Regorafenib)
Regonat (Regorafenib) is used in the treatment of:
- Metastatic Colorectal Cancer (mCRC) – in patients previously treated with chemotherapy and biological agents
- Gastrointestinal Stromal Tumor (GIST) – after disease progression on imatinib and sunitinib
- Hepatocellular Carcinoma (HCC) – in patients previously treated with sorafenib
Side Effects of Regonat Tablet (Regorafenib)
Like most cancer therapies, Regonat may cause side effects, some of which can be serious and require monitoring.
- Fatigue
- Decreased appetite
- Diarrhea
- Weight loss
- High blood pressure
- Skin peeling or rash, especially on hands and feet (hand-foot skin reaction)
FAQs of Regonat Tablet (Regorafenib)
Q1: How should I take Regonat?
A: Take Regonat exactly as prescribed, usually once daily for 21 days followed by a 7-day break (28-day cycle). Swallow with water after a low-fat meal.
Q2: What should I do if I miss a dose?
A: Skip the missed dose if it's close to your next one. Do not double up. Inform your doctor if you miss multiple doses.
Q3: Can I stop taking Regonat if I feel better?
A: No. Never stop or adjust the dose without consulting your doctor, as cancer can progress rapidly.
Q4: Is Regonat a form of chemotherapy?
A: Regonat is a targeted therapy, not traditional chemotherapy. It works by targeting specific enzymes and pathways that cancer cells use to grow.
Q5: How will I be monitored during treatment?
A: Your doctor will conduct regular blood tests, blood pressure checks, and liver function tests to monitor safety and effectiveness.
Interactions of Regonat Tablet (Regorafenib)
Regorafenib can interact with several other drugs:
Avoid or consult your doctor before combining with:
- Strong CYP3A4 inhibitors or inducers (e.g., ketoconazole, rifampin)
- Blood thinners (e.g., warfarin)
- St. John’s Wort (herbal supplement)
- Anti-seizure medications (e.g., phenytoin)
Alcohol consumption should be minimized due to the risk of liver toxicity.
| Manufacturer | : | Natco Pharma, India |
| Trade Name | : | |
| Generic Search | : | Regorafenib |
| Strength | : | 40 mg |
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