Prepit Capsule (Aprepitant + Aprepitant)
Prepit Capsule (Aprepitant) is a medication used to prevent nausea and vomiting associated with chemotherapy, particularly in cancer patients undergoing cisplatin-based chemotherapy.
Aprepitant is a medication primarily used to prevent nausea and vomiting associated with chemotherapy and surgery. It functions as a neurokinin-1 (NK1) receptor antagonist, blocking the action of substance P, a neuropeptide linked to vomiting reflexes.
Prepit Capsule of Precautions:
Before taking aprepitant, inform your healthcare provider if you:
- Have liver disease.
- Are pregnant, plan to become pregnant, or are breastfeeding.
Aprepitant can interact with hormonal contraceptives, potentially reducing their effectiveness. It's recommended to use an additional non-hormonal method of birth control (e.g., condoms, spermicide) during treatment and for one month after the final dose.
Prepit Capsule of Uses:
Aprepitant is prescribed to:
- Prevent acute and delayed nausea and vomiting caused by highly emetogenic chemotherapy.
- Prevent postoperative nausea and vomiting.
It is typically used in combination with other antiemetic agents, such as 5-HT3 antagonists (e.g., ondansetron) and corticosteroids (e.g., dexamethasone), to enhance its efficacy.
Prepit Capsule of Side Effects:
Common side effects of aprepitant may include:
- Weakness
- Tiredness
- Dizziness
- Diarrhea
- Constipation
- Gas
- Stomach pain
- Heartburn
- Nausea
- Hiccups
- Loss of appetite
- Headache
- Fever
- Hair loss
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
- Hives
- Rash
- Itching
- Skin peeling or blisters
- Difficulty breathing or swallowing
Prepit Capsule of FAQs:
Q: How should I take aprepitant?
Take aprepitant by mouth with a glass of water. Follow the directions on the prescription label. Usually, you will take your first dose one hour before your chemotherapy begins, and then once daily in the morning for the next 2 days after your chemotherapy treatment. This medication may be taken with or without food. Do not take more often than directed.
Q: What should I do if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Q: Can I take aprepitant if I am pregnant or breastfeeding?
If you are pregnant, plan to become pregnant, or are breastfeeding, consult your healthcare provider before using aprepitant. Aprepitant can interact with hormonal contraceptives, potentially reducing their effectiveness. It's recommended to use an additional non-hormonal method of birth control during treatment and for one month after the final dose.
Q: Are there any foods or drinks I should avoid while taking aprepitant?Unless your doctor tells you otherwise, continue your normal diet.
Prepit Capsule of Interactions :
Aprepitant may interact with several medications, including:
- Cisapride
- Flibanserin
- Lomitapide
- Pimozide
- Diltiazem
- Medications for fungal infections (e.g., ketoconazole, itraconazole)
- Medications for HIV
- Medications for seizures or epilepsy (e.g., carbamazepine, phenytoin)
- Medications used for sleep or anxiety disorders (e.g., alprazolam, diazepam, midazolam)
- Nefazodone
- Paroxetine
- Ranolazine
- Rifampin
This is not an exhaustive list. Always inform your healthcare provider about all the medications and supplements you are taking to ensure safety.
| Manufacturer | : | Khandelwal Lab, India |
| Trade Name | : | |
| Generic Search | : | Aprepitant |
| Strength | : | 125mg+ 80mg |








