Panderm ++ Cream (Clobetasol + Miconazole + Neomycin) | Used to Treat Fungal Skin Infections with Bacterial Infection and Inflammation

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Panderm ++ Cream is a topical antifungal, antibacterial, and anti-inflammatory medicine used to treat skin infections caused by fungi, bacteria, or inflammation. It helps relieve itching, redness, swelling, and irritation associated with various skin conditions.

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Panderm + + Cream
PackageQTYPriceAdd To Cart
1 Tube $3.92
3 Tube/s $11.76
6 Tube/s $23.52

Product Overview

Panderm ++ Cream is a high-potency, broad-spectrum topical combination designed for the management of complex skin infections characterized by both inflammation and microbial involvement. By integrating a potent corticosteroid, a broad-spectrum antifungal, and an aminoglycoside antibiotic, this formula provides a comprehensive solution for skin conditions where inflammation is complicated by secondary bacterial or fungal colonization.

Product Composition

  • Clobetasol Propionate 0.05 percent w/w
  • Miconazole Nitrate 2.0 percent w/w
  • Neomycin Sulphate 0.5 percent w/w
  • Cream base q.s.

Product Specification

FeatureDetails
Brand NamePanderm ++ Cream
Therapeutic CategoryTopical Corticosteroid + Antifungal + Antibiotic
FormTopical Cream
Primary IndicationInflammatory skin infections with fungal/bacterial components
Storage RequirementsStore in a cool, dry place; do not freeze

 

Mechanism of Action

  • Clobetasol Propionate: A super-potent corticosteroid that provides rapid relief from inflammation, redness, itching, and swelling by suppressing the immune response at the site of application.
  • Miconazole Nitrate: An antifungal agent that inhibits the synthesis of ergosterol, a vital component of fungal cell membranes, leading to the inhibition of growth and destruction of fungi and yeasts.
  • Neomycin Sulphate: An aminoglycoside antibiotic that interferes with bacterial protein synthesis, effectively eliminating susceptible bacteria often responsible for secondary infections in damaged skin.

Key Benefits

  • Offers a multi-targeted approach to treating complex, infected skin lesions
  • Provides rapid reduction of painful or uncomfortable inflammatory symptoms
  • Effectively clears fungal and yeast overgrowth
  • Protects against and treats secondary bacterial infections
  • Simplifies the treatment regimen for mixed dermatological infections

Precautions

Use Only Under Medical Supervision

  • Panderm Cream ++ contains a potent combination of clobetasol, miconazole, and neomycin and should be used only if prescribed by a doctor
  • Do not use for longer duration than recommended

Avoid Prolonged Use

  • Long term use of clobetasol may cause skin thinning and other steroid related side effects
  • Follow prescribed treatment duration strictly

External Use Only

  • Apply only on affected skin areas
  • Avoid contact with eyes, mouth, and broken or sensitive skin

Avoid Occlusive Dressings

  • Do not cover treated area with tight bandages unless advised by a doctor
  • This may increase absorption and side effects

Monitor for Allergic Reactions

  • Watch for signs like increased redness, itching, or swelling
  • Discontinue use and consult a doctor if severe reaction occurs

Special Populations

  • Use with caution during pregnancy and breastfeeding
  • Pediatric use should be strictly supervised
 
Precaution AreaGuidance
UsageUse only as prescribed by doctor
DurationDo not use for long term without supervision
ApplicationApply thin layer on affected area only
Sensitive AreasAvoid eyes, mouth, and broken skin
DressingsAvoid occlusive bandaging unless advised
Special CasesUse cautiously in pregnancy and children

Usage

Dosage & Application

  • Apply a thin layer of the cream to the affected area only as directed by your physician

  • Use the medication strictly for the duration prescribed; do not extend treatment without professional approval

  • Apply the cream gently and sparingly; avoid excessive application, as more is not better and can increase the risk of side effects

  • Wash your hands thoroughly after application to prevent accidental transfer to other areas or the eyes

Important Precautions

  • For external use only. Do not ingest or apply to the eyes, mouth, or mucous membranes

  • Do not use an occlusive dressing (tight bandages or plastic wraps) over the treated area unless specifically instructed by your doctor

  • Avoid applying this cream to open wounds, ulcerated skin, or large surface areas without clinical oversight

  • If you experience any signs of skin thinning, burning, stinging, or redness, discontinue use and consult your doctor immediately

Treatment Application Table

ProcedureGuideline
FrequencyUsually 1–2 times daily, as instructed
TechniqueApply a thin, even layer to the affected site
HygieneClean and dry the area before application
RestrictionAvoid use on the face, groin, or underarms unless directed

Uses

  • Management of inflammatory dermatoses complicated by secondary fungal or bacterial infections

  • Relief of intense pruritus (itching) and inflammation associated with eczematous conditions

  • Treatment of dermatophyte infections involving secondary bacterial colonization

  • Rapid reduction of localized erythema, swelling, and discomfort in infected skin sites

  • Comprehensive care for mixed microbial skin disorders requiring concurrent anti-inflammatory and anti-infective action

Side Effects

Common Skin Reactions

  • Burning or stinging sensation at application site
  • Redness, itching, or irritation
  • Dryness or peeling of skin

Steroid Related Effects (Clobetasol)

  • Skin thinning with prolonged use
  • Stretch marks or visible blood vessels
  • Delayed wound healing in treated area

Antibiotic Related Effects (Neomycin)

  • Allergic skin reactions such as rash or contact dermatitis
  • Increased sensitivity on repeated use

Fungal Treatment Effects (Miconazole)

  • Mild irritation or discomfort initially
  • Rare allergic reactions

Serious but Uncommon Effects

  • Severe skin irritation or swelling
  • Secondary infections due to prolonged steroid use
  • Hypersensitivity reactions
 
Side Effect TypeDetails
Common EffectsBurning, itching, redness
Steroid EffectsSkin thinning, stretch marks
Antibiotic EffectsAllergic rash, sensitivity
Antifungal EffectsMild irritation
Serious EffectsSevere allergy, secondary infection

FAQs

Q: What is Panderm ++ Cream used for?

A: Panderm ++ Cream is used for the topical treatment of inflammatory skin conditions that are complicated by fungal or bacterial infections. It helps to reduce symptoms like redness, itching, and swelling while simultaneously fighting the underlying infection.

Q: Can I use this cream on my face?

A: Topical corticosteroids like Clobetasol are generally very potent. You should only apply this to the face if specifically instructed by a dermatologist, and for the shortest duration possible, as it may cause skin thinning or other side effects if used improperly on delicate facial skin.

Q: How long should I use this cream?

A: This cream should be used only for the duration specified by your doctor. Due to the presence of a potent corticosteroid, prolonged or continuous use should be avoided to prevent systemic absorption or adverse dermatological effects.

Q: Can I apply this under a bandage or airtight dressing?

A: You should avoid covering the area with airtight bandages or dressings (occlusive dressing) unless specifically directed by your doctor. Doing so can significantly increase the absorption of the medication into the bloodstream, which may lead to unwanted side effects.

Q: Is it safe for children?

A: The use of high-potency corticosteroids in children requires extreme caution and should only be done under strict medical supervision, as children have a higher risk of systemic absorption and potential impact on growth.

Q: What should I do if my skin condition does not improve?

A: If there is no significant improvement after several days of treatment, or if the condition worsens, stop using the cream and consult your healthcare provider immediately.

Interactions

Other Topical Steroid or Antifungal Products

  • Avoid using other steroid, antifungal, or antibiotic creams at the same time
  • May increase risk of skin thinning, irritation, or reduced effectiveness

Harsh Skin Care Products

  • Do not use alcohol-based toners, scrubs, or strong exfoliating agents
  • These may worsen irritation and damage skin barrier

Other Antibiotics (Topical or Oral)

  • Concurrent use with other antibiotics should only be done under medical advice
  • May increase risk of side effects or resistance

Occlusive Dressings and Bandages

  • Avoid covering the treated area tightly unless prescribed
  • Can increase absorption of clobetasol and risk of side effects

Vaccines and Immune Response

  • Prolonged steroid use may slightly affect immune response
  • Inform doctor if undergoing vaccination
 
Interaction TypeRecommendation
Other Steroid CreamsAvoid combination unless prescribed
Antifungal/Antibiotic CreamsUse only under medical supervision
Harsh Skincare ProductsDo not use scrubs or alcohol-based products
Occlusive DressingsAvoid unless advised
VaccinationInform doctor before use
More Information
Manufacturer:Macleods Pharma, India
Trade Name:
Generic Search:Clobetasol + Miconazole+ Neomycin
Strength:15g
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