Meftal Tablet (Mefenamic Acid) | Ponstel | Used to Get Fast Relief from Mild to Moderate Pain, and Menstrual Cramps
MEFTAL TABLET used to relieve mild to moderate pain and inflammation associated with muscle disorders, rheumatic, joint, headache, trauma, toothache and pain after surgery surgery or childbirth. It belongs to the group of NSAID (non-steroidal anti-inflammatory drugs).
Product Overview
Meftal Tablet is primarily utilized for the short-term management of mild to moderate pain and the treatment of inflammation, including menstrual cramps (dysmenorrhea), headaches, toothaches, and muscle pain. It is a widely used non-steroidal anti-inflammatory drug (NSAID) containing Mefenamic Acid. Meftal is particularly effective in addressing gynecological pain and musculoskeletal discomfort. By inhibiting the enzymes responsible for pain and swelling, it provides rapid symptomatic relief, allowing for improved mobility and comfort during acute episodes of pain.
Product Composition
- Active Ingredient: Mefenamic Acid (Available in 250 mg and 500 mg strengths)
- Excipients: Microcrystalline cellulose, Corn starch, Magnesium stearate, Sodium starch glycolate, and Colloidal silicon dioxide.
Product Specification
| Feature | Details |
| Drug Class | NSAID (Fenamate group) |
| Pharmacological Action | Analgesic, Anti-inflammatory, Antipyretic |
| Administration | Oral |
| Primary Indication | Menstrual pain and inflammation |
| Onset of Action | 30 to 60 minutes |
| Duration of Effect | 6 to 8 hours |
Mechanism of Action
- COX Enzyme Inhibition: Mefenamic Acid inhibits both cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes.
- Prostaglandin Synthesis: By blocking these enzymes, it reduces the synthesis of prostaglandins—chemicals in the body that signal pain and cause inflammation and fever.
- Peripheral Action: It acts primarily at the site of injury or inflammation to reduce swelling and sensitivity.
- Uterine Contraction Reduction: In cases of menstrual pain, it lowers prostaglandin levels in the uterine lining, which decreases the intensity of uterine contractions.
Key Benefits
- Superior Menstrual Relief: Highly effective at treating primary dysmenorrhea (painful periods) and reducing heavy menstrual flow.
- Multi-Purpose Analgesic: Provides relief from various types of pain, including dental pain, muscle aches, and post-surgical discomfort.
- Anti-Inflammatory Properties: Reduces joint swelling and stiffness associated with conditions like osteoarthritis and rheumatoid arthritis.
- Fever Reduction: Acts as an antipyretic to lower high body temperatures during infections.
- Rapid Absorption: The tablet formulation is designed to be absorbed quickly for fast-acting pain management.
- Versatile Dosing: Available in multiple strengths to cater to different levels of pain severity.
Precautions
Important precautions for Meftal Tablet (Mefenamic Acid)
Gastrointestinal precautions
- May cause stomach irritation, use with food to reduce discomfort
- Avoid in patients with history of ulcers or gastrointestinal bleeding
- Long term use may increase risk of gastric complications
- Report symptoms like severe stomach pain or black stools immediately
Kidney and liver precautions
- Use with caution in kidney or liver impairment
- Prolonged use may affect kidney function
- Regular monitoring may be required in high risk patients
- Avoid dehydration during treatment
Cardiovascular precautions
- Use cautiously in patients with heart disease or high blood pressure
- Long term use may increase cardiovascular risk
- Monitor for swelling or unusual weight gain
Allergy and sensitivity precautions
- Avoid in individuals with known NSAID allergy
- May cause skin reactions or hypersensitivity in some patients
- Discontinue if rash or breathing difficulty occurs
General usage precautions
- Do not exceed recommended dosage or duration
- Not intended for prolonged continuous use without guidance
- Avoid combining with other NSAIDs unless advised
- Use cautiously in elderly patients
Safety overview table
| Area of caution | Precaution guidance |
|---|---|
| Gastrointestinal | Risk of irritation, ulcers, and bleeding |
| Kidney function | Monitor with prolonged use |
| Cardiovascular | Use cautiously in heart conditions |
| Allergy risk | Avoid in NSAID sensitive individuals |
Usage
Dosage
Dosage should be determined by a healthcare professional based on the severity of the pain and the patient's medical history. It is typically prescribed for short-term use (not exceeding 7 days).
| Condition | Typical Dosage | Frequency |
| Mild to Moderate Pain | 500 mg initial dose | Followed by 250 mg every 6 hours |
| Menstrual Pain (Dysmenorrhea) | 500 mg initial dose | Followed by 250 mg every 6 hours |
| Heavy Menstrual Bleeding | 500 mg | Three times daily during the period |
| Arthritis/Joint Pain | 250 mg to 500 mg | Two to three times daily |
Administration
With Food: Always take Meftal with food, milk, or an antacid to minimize the risk of stomach irritation or gastric ulcers.
Swallow Whole: Do not crush or chew the tablet. Swallow it whole with a full glass of water.
Duration: Use the lowest effective dose for the shortest duration necessary to control symptoms.
Hydration: Maintain adequate fluid intake while taking this medication to support kidney function.
Missed Dose: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed one. Do not double the dose.
Alcohol: Avoid consuming alcohol while taking Meftal, as it increases the risk of stomach bleeding.
Uses
Primary Dysmenorrhea: Relieves painful menstrual cramps by reducing prostaglandin levels and uterine contractions.
Menorrhagia: Helps reduce excessive blood loss during menstrual cycles.
Rheumatoid Arthritis & Osteoarthritis: Manages pain, swelling, and joint stiffness associated with chronic inflammatory conditions.
Dental Pain: Provides relief from pain following dental procedures or toothaches.
Post-Operative Pain: Used to manage moderate pain following surgical or orthopedic procedures.
Soft Tissue Injuries: Effectively treats pain and inflammation from sprains, strains, and sports injuries.
Pyrexia (Fever): Used as a secondary treatment to lower high body temperature in adults and children (in appropriate formulations).
Side effects
Common side effects
- Nausea or vomiting
- Stomach pain or discomfort
- Diarrhea or loose stools
- Indigestion or heartburn
Gastrointestinal effects
- Gastric irritation or inflammation
- Loss of appetite
- Bloating or gas
- Risk of stomach ulcers with prolonged use
Less common side effects
- Headache or dizziness
- Skin rash or itching
- Drowsiness or fatigue
- Ringing in the ears
Serious side effects
- Gastrointestinal bleeding with symptoms like black stools
- Severe allergic reactions such as swelling or breathing difficulty
- Kidney function changes or reduced urine output
- Liver dysfunction with symptoms like yellowing of skin or eyes
Side effects summary table
| System affected | Possible reaction |
|---|---|
| Gastrointestinal | Nausea, pain, diarrhea, ulcers |
| Nervous system | Headache, dizziness, drowsiness |
| Skin | Rash, itching, allergic reactions |
| Renal | Kidney function changes |
| Hepatic | Liver dysfunction symptoms |
FAQs
Q: What is the product used for?
A: Meftal is primarily used for the short-term relief of mild to moderate pain. It is highly effective for menstrual cramps (dysmenorrhea), muscle aches, dental pain, and joint pain caused by inflammation. It also helps reduce fever.
Q: How should I take Meftal?
A: The tablet should be swallowed whole with a glass of water. It is best taken with food or milk to protect your stomach and reduce the risk of digestive upset.
Q: How quickly does it work?
A: Most people begin to feel pain relief within 30 to 60 minutes after taking the tablet. The effects typically last for about 6 to 8 hours.
Q: Can I take this for heavy menstrual bleeding?
A: Yes, Mefenamic Acid is often prescribed to reduce heavy blood loss during periods (menorrhagia) by lowering the level of prostaglandins in the lining of the uterus.
Q: Are there any common side effects?
A: Some individuals may experience stomach pain, nausea, heartburn, or diarrhea. If you develop a severe skin rash or persistent stomach discomfort, stop taking the medication and consult your doctor.
Q: Can I take Meftal if I have asthma?
A: You should consult your doctor first. Some people with asthma may be sensitive to NSAIDs like Meftal, which could potentially trigger an asthma attack or breathing difficulties.
Q: Is it safe to take Meftal during pregnancy?
A: Meftal is generally not recommended during pregnancy, especially during the third trimester, as it may affect the baby’s circulation or delay labor. Always seek medical advice before use if you are pregnant or breastfeeding.
Interactions
Drug interactions of Meftal Tablet (Mefenamic Acid)
Pain relief and NSAID interactions
- Other NSAIDs may increase risk of stomach irritation and bleeding
- Aspirin may increase gastrointestinal side effects
- Combination with multiple painkillers should be avoided
Blood thinning medicine interactions
- Anticoagulants may increase risk of bleeding
- Antiplatelet drugs may enhance bleeding tendency
- Monitoring is required when used together
Kidney and blood pressure medicine interactions
- Diuretics may reduce effectiveness and affect kidney function
- ACE inhibitors may have reduced blood pressure control
- Combined use may increase risk of kidney complications
Steroid and anti inflammatory interactions
- Corticosteroids may increase risk of gastrointestinal side effects
- Combination may require protective measures for stomach lining
Other medicine considerations
- Lithium levels may increase when used together
- Methotrexate toxicity risk may increase
- Alcohol may increase risk of stomach irritation and bleeding
Drug interactions table
| Drug class | Interaction effect |
|---|---|
| NSAIDs and aspirin | Increased risk of gastric irritation and bleeding |
| Anticoagulants and antiplatelets | Higher bleeding risk |
| Diuretics and ACE inhibitors | Reduced effectiveness and kidney risk |
| Corticosteroids | Increased gastrointestinal side effects |
| Lithium and methotrexate | Increased toxicity risk |
| Manufacturer | : | Blue Cross Laboratories Ltd |
| Trade Name | : | Ponstel |
| Generic Search | : | Mefenamic acid |
| Strength | : | 250mg, 500mg |
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