Espra XN Tablet (Naproxen + Esomeprazole)

What is Espra XN Tablet?

Espra XN tablet is a combination medication that contains two active ingredients: Naproxen and Esomeprazole. Naproxen is a nonsteroidal anti-inflammatory drug (NSAID), while Esomeprazole is a proton pump inhibitor (PPI). The tablet is used to relieve symptoms associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and other inflammatory conditions.

Naproxen is used to relieve pain, swelling, and inflammation. It works by blocking the production of certain natural substances that cause inflammation in the body. Naproxen is used to relieve pain and inflammation associated with conditions like arthritis, menstrual cramps, and other Joint pain conditions. Naproxen, one of the active ingredients in Espra XN tablets can be used to relieve mild-to-moderate migraines. It works by reducing the inflammation that can trigger migraine headaches.
Esomeprazole is used to reduce the amount of acid produced by the stomach. It is used to treat gastroesophageal reflux disease (GERD) and other conditions where there is excess acid production in the stomach. Esomeprazole works by inhibiting the proton pump, which is responsible for producing stomach acid.

Together, Naproxen and Esomeprazole work to relieve pain and inflammation while also reducing the risk of gastrointestinal side effects like stomach ulcers and bleeding. Espra XN tablet is available in various strengths, and the dosage will depend on the patient's age, weight, and medical condition. It is important to take the tablet as directed by the doctor and to avoid taking more than the recommended dose.

Like all medications, Espra XN tablet may cause side effects. Common side effects include headache, dizziness, nausea, vomiting, stomach pain, and diarrhea. In rare cases, the medication may cause serious side effects such as liver damage, kidney damage, or an allergic reaction. If you experience any side effects, it is important to consult your doctor

How Naproxen and Esomeprazole works?

Naproxen belongs to a class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). It works by inhibiting the production of prostaglandins, which are chemicals that cause pain and inflammation in the body. Naproxen blocks the enzyme cyclooxygenase (COX), which is responsible for producing prostaglandins. By reducing the production of prostaglandins, naproxen helps to relieve pain, reduce inflammation, and lower fever.
Esomeprazole belongs to a class of medications called proton pump inhibitors (PPIs). It works by reducing the amount of acid produced by the stomach. Esomeprazole inhibits the proton pump, which is responsible for producing stomach acid. By reducing the amount of acid produced, esomeprazole helps to relieve symptoms of gastroesophageal reflux disease (GERD), heartburn, and other conditions where there is excess acid production in the stomach.

When combined, naproxen and esomeprazole work together to provide pain relief and reduce inflammation, while also protecting the stomach from the harmful effects of NSAIDs. Naproxen can cause stomach irritation, ulcers, and bleeding in some people, but esomeprazole helps to reduce the risk of these side effects by lowering the amount of acid in the stomach. This combination medication is often prescribed to treat conditions like osteoarthritis, rheumatoid arthritis, and other inflammatory conditions where pain and inflammation are present, and the risk of stomach irritation is a concern.

Dosage of VIMOVO

The dosage of Espra XN tablet (Naproxen + Esomeprazole) will depend on the patient's age, weight, medical condition, and other factors. It is important to take the medication as directed by the doctor or as instructed on the label.

In general, the recommended dosage for adults is one tablet of Espra XN 375/20 (which contains 375 mg of Naproxen and 20 mg of Esomeprazole) twice daily, taken orally with or without food. The maximum daily dose should not exceed two tablets per day.
The tablet should be swallowed whole with a glass of water, and should not be crushed, chewed, or broken. It is important to take the medication at the same time each day to maintain a consistent level of the drug in the body.

Dosage adjustments may be necessary for elderly patients, patients with kidney or liver problems, or patients taking certain other medications. It is important to inform your doctor of any other medications you are taking before starting Espra XN tablet.

Do not take more than the recommended dose of Espra XN tablet, as this can increase the risk of side effects. If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed dose.

Uses

Espra XN Tablet (Naproxen + Esomeprazole) is a combination medication that is used to relieve pain, and inflammation, and reduce stomach acid production. It is commonly prescribed to treat the following conditions:

1. Osteoarthritis: Espra XN Tablet is used to relieve pain and inflammation associated with osteoarthritis, a condition that causes the degeneration of joint cartilage and bone.

2. Rheumatoid arthritis: The medication is also used to reduce pain and inflammation in patients with rheumatoid arthritis, a chronic autoimmune disorder that affects the joints.

3. Ankylosing spondylitis: Espra XN Tablet may be prescribed to treat ankylosing spondylitis, a type of arthritis that primarily affects the spine.

4. Gastroesophageal reflux disease (GERD): The medication is used to reduce the amount of acid produced by the stomach in patients with GERD, a condition in which stomach acid flows back into the esophagus, causing heartburn and other symptoms.

Espra XN Tablet works by combining the anti-inflammatory properties of Naproxen with the acid-reducing effects of Esomeprazole. Naproxen helps to relieve pain and inflammation, while Esomeprazole helps to reduce the risk of gastrointestinal side effects like stomach ulcers and bleeding.

Side effects

1. Headache
2. Dizziness
3. Nausea
4. Indigestion
5. Diarrhea
6. Abdominal pain
7. Constipation

Less common but more serious side effects of Espra XN Tablet include:

1. Allergic reactions, such as hives, swelling of the face, lips, tongue, or throat, or difficulty breathing
2. Severe stomach pain, cramping, or bloating
3. Black, tarry, or bloody stools
4. Chest pain, shortness of breath, or coughing up blood
5. Signs of liver problems, such as yellowing of the skin or eyes, dark urine, or clay-colored stools
6. Signs of kidney problems, such as decreased urination or swelling of the legs, ankles, or feet
7. Signs of a heart attack, such as chest pain, pressure, or discomfort; sweating; or pain that spreads to the arm, neck, or jaw.

If you experience any of these side effects, seek immediate medical attention. It is important to inform your doctor of any side effects or symptoms you experience while taking Espra XN tablets.

FAQ

Q: What is Espra XN Tablet used for?

A: Espra XN Tablet is a combination medication used to relieve pain and inflammation, and reduce stomach acid production. It is commonly used to treat conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and gastroesophageal reflux disease (GERD).

Q: How should I take Espra XN Tablet?

A: Espra XN Tablet should be taken as directed by your doctor or as instructed on the label. It is usually taken orally with or without food. The tablet should be swallowed whole with a glass of water and should not be crushed, chewed, or broken.

Q: What are the serious side effects of Espra XN Tablet?

A: The serious side effects of Espra XN Tablet include allergic reactions, severe stomach pain, cramping, or bloating, black, tarry, or bloody stools, chest pain, shortness of breath, or coughing up blood, signs of liver or kidney problems, and signs of a heart attack.

Q: Can I take Espra XN Tablet for Magraine?

A: Naproxen, one of the active ingredients in Espra XN, is a nonsteroidal anti-inflammatory drug (NSAID) that can be used to relieve mild-to-moderate migraines. It works by reducing the inflammation that can trigger migraine headaches.

Q: Can Espra XN Tablet be taken during pregnancy or breastfeeding?

A: It is not recommended to take Espra XN Tablet during pregnancy or breastfeeding without consulting your doctor. The medication may harm the developing fetus or pass into breast milk and harm the nursing baby.

Q: Can Espra XN Tablet be taken with other medications?

A: It is important to inform your doctor of any other medications you are taking before starting Espra XN Tablet. Some medications may interact with Espra XN Tablet, including blood thinners, aspirin, and other nonsteroidal anti-inflammatory drugs (NSAIDs), among others.

Q: Can I drink alcohol while taking Espra XN Tablet?

 

A: It is not recommended to drink alcohol while taking Espra XN Tablet, as it may increase the risk of stomach bleeding and other side effects.

Q: What should I do if I miss a dose of Espra XN Tablet?

A: If you miss a dose of Espra XN Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed dose.

Interactions

Espra XN Tablet (Naproxen + Esomeprazole) can interact with other medications, vitamins, and herbal supplements.

1. Other nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin, ibuprofen, and diclofenac
2. Blood thinners, such as warfarin
3. Corticosteroids, such as prednisone
4. Selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine and sertraline
5. Methotrexate
6. Antidepressants
7. Lithium
8. Diuretics, such as furosemide
9. Probenecid
10. Digoxin
11. Tacrolimus

These are not the only medications that may interact with Espra XN Tablet, so it is important to talk to your doctor or pharmacist before taking any new medications while using Espra XN Tablet.