{"id":1184,"date":"2026-09-03T10:11:23","date_gmt":"2026-09-03T10:11:23","guid":{"rendered":"https:\/\/www.onlinegenericmedicine.com\/news\/?p=1184"},"modified":"2026-09-03T10:15:37","modified_gmt":"2026-09-03T10:15:37","slug":"tadalafil-linked-to-higher-glaucoma-risk-in-new-study","status":"publish","type":"post","link":"https:\/\/www.onlinegenericmedicine.com\/news\/tadalafil-linked-to-higher-glaucoma-risk-in-new-study\/","title":{"rendered":"Tadalafil Linked to Higher Glaucoma Risk in New Study"},"content":{"rendered":"\n<div class=\"wp-block-columns alignwide is-layout-flex wp-container-core-columns-is-layout-f56f613f wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"wp-block-aioseo-table-of-contents\"><ul><\/ul><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">A widely used <a href=\"https:\/\/www.onlinegenericmedicine.com\/mens-health\/erectile-dysfunction-pills\" title=\"\">medication for erectile dysfunction<\/a> and urinary symptoms associated with an enlarged prostate has been linked to a higher risk of glaucoma in a new multinational study.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The medication, <strong><a href=\"https:\/\/www.onlinegenericmedicine.com\/composition\/tadalafil\" title=\"\">tadalafil<\/a><\/strong>, is a phosphodiesterase type 5 (PDE5) inhibitor also known by the brand name Cialis. While tadalafil is commonly prescribed for erectile dysfunction, it may also be used for the treatment of lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH).<\/p>\n\n\n\n<h2 id=\"aioseo-what-did-the-study-find\" class=\"wp-block-heading has-large-font-size\"><strong>What Did the Study Find?<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The new study followed <strong>73,854 men aged 40 and older<\/strong>, including 36,927 tadalafil users and an equal number of matched participants who did not use <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK549843\/\" target=\"_blank\" rel=\"noopener nofollow\" title=\"\">PDE5 inhibitors<\/a>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Over a follow-up period of up to five years, researchers found that men using tadalafil had a <strong>22% higher risk of developing glaucoma<\/strong> compared with the matched non-PDE5 inhibitor group.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The study also reported:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>A <strong>32% higher risk of ocular hypertension<\/strong><\/li>\n\n\n\n<li>A <strong>33% higher risk of primary open-angle glaucoma<\/strong><\/li>\n\n\n\n<li>A <strong>33% higher likelihood of starting <a href=\"https:\/\/www.onlinegenericmedicine.com\/all-category\/eye-ear-care\/glaucoma-medications\" title=\"\">glaucoma treatment<\/a><\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">The five-year cumulative incidence of glaucoma was <strong>3.93% among tadalafil users<\/strong>, compared with <strong>3.16% in the non-user group<\/strong>.<\/p>\n\n\n\n<h2 id=\"aioseo-does-this-mean-tadalafil-causes-glaucoma\" class=\"wp-block-heading has-large-font-size\"><strong>Does This Mean Tadalafil Causes Glaucoma?<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Not necessarily. This is an important distinction.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The study found an <strong>association<\/strong> between tadalafil use and a higher risk of glaucoma, but it was a retrospective observational study. This means the findings do not prove that tadalafil directly causes glaucoma.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">More research is needed to understand whether long-term tadalafil use directly affects eye pressure, blood flow, or other factors involved in glaucoma development.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The results should therefore be interpreted carefully and should not be considered a reason to stop prescribed tadalafil without consulting a healthcare professional.<\/p>\n\n\n\n<h2 id=\"aioseo-why-might-tadalafil-affect-eye-health\" class=\"wp-block-heading has-large-font-size\"><strong>Why Might Tadalafil Affect Eye Health?<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Tadalafil works by inhibiting an enzyme called phosphodiesterase type 5 (PDE5). This helps relax blood vessels and improve blood flow, which is why the medication can help with erectile dysfunction.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">However, PDE5 inhibitors may also influence blood flow and pressure within the eye. Previous research has linked this class of medications to certain visual side effects and eye-related complications.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Researchers say further studies are needed to understand exactly how long-term tadalafil use might influence ocular physiology and glaucoma risk.<\/p>\n\n\n\n<h2 id=\"aioseo-who-may-need-extra-eye-monitoring\" class=\"wp-block-heading has-large-font-size\"><strong>Who May Need Extra Eye Monitoring?<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The researchers suggested that enhanced ophthalmic monitoring may be considered for people taking tadalafil long term, especially those with existing risk factors for glaucoma.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">People may wish to discuss regular eye examinations with their doctor if they have:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>A family history of glaucoma<\/li>\n\n\n\n<li>Ocular hypertension or previously elevated eye pressure<\/li>\n\n\n\n<li>Existing glaucoma<\/li>\n\n\n\n<li>High myopia (severe short-sightedness)<\/li>\n\n\n\n<li>A need for long-term daily tadalafil therapy<\/li>\n<\/ul>\n\n\n\n<h2 id=\"aioseo-what-should-tadalafil-users-do\" class=\"wp-block-heading has-large-font-size\"><strong>What Should Tadalafil Users Do?<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Do not stop taking tadalafil suddenly based only on this study. If you use tadalafil for erectile dysfunction or urinary symptoms and have concerns about glaucoma, speak with your doctor or an eye specialist.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Regular comprehensive eye examinations may be particularly important for people using tadalafil long term or those who already have glaucoma risk factors.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Seek prompt medical attention if you experience sudden or severe vision changes, as these may require urgent evaluation.<\/p>\n\n\n\n<h2 id=\"aioseo-the-bottom-line\" class=\"wp-block-heading has-large-font-size\"><strong>The Bottom Line<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">This large study found that long-term <a href=\"https:\/\/www.onlinegenericmedicine.com\/composition\/tadalafil\" title=\"\">tadalafil<\/a> use for lower urinary tract symptoms was associated with a higher risk of glaucoma and increased eye pressure. However, the findings do not prove that tadalafil causes glaucoma, and the results should not be generalized automatically to occasional or short-term tadalafil use for erectile dysfunction.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Further research is needed to confirm the relationship and understand the underlying mechanism. For now, patients using long-term tadalafil\u2014particularly those with known glaucoma risk factors\u2014may benefit from discussing regular eye monitoring with a qualified healthcare professional.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Disclaimer:<\/strong> This article is for informational purposes only and should not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional regarding medications and changes to your treatment plan.<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>A widely used medication for erectile dysfunction and urinary symptoms associated with an enlarged prostate has been linked to a higher risk of glaucoma in a new multinational study. The medication, tadalafil, is a phosphodiesterase type 5 (PDE5) inhibitor also known by the brand name Cialis. While tadalafil is commonly prescribed for erectile dysfunction, it [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":1185,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"footnotes":""},"categories":[42,4],"tags":[272,328,327,273],"class_list":["post-1184","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-eye-ear-care","category-mens-health","tag-cialis","tag-glaucoma-treatment","tag-medication-for-erectile-dysfunction","tag-tadalafil"],"aioseo_notices":[],"rttpg_featured_image_url":{"full":["https:\/\/www.onlinegenericmedicine.com\/news\/wp-content\/uploads\/2026\/09\/Tadalafil-Linked-to-Higher-Glaucoma-Risk-in-New-Study.png",600,400,false],"landscape":["https:\/\/www.onlinegenericmedicine.com\/news\/wp-content\/uploads\/2026\/09\/Tadalafil-Linked-to-Higher-Glaucoma-Risk-in-New-Study.png",600,400,false],"portraits":["https:\/\/www.onlinegenericmedicine.com\/news\/wp-content\/uploads\/2026\/09\/Tadalafil-Linked-to-Higher-Glaucoma-Risk-in-New-Study.png",600,400,false],"thumbnail":["https:\/\/www.onlinegenericmedicine.com\/news\/wp-content\/uploads\/2026\/09\/Tadalafil-Linked-to-Higher-Glaucoma-Risk-in-New-Study-150x150.png",150,150,true],"medium":["https:\/\/www.onlinegenericmedicine.com\/news\/wp-content\/uploads\/2026\/09\/Tadalafil-Linked-to-Higher-Glaucoma-Risk-in-New-Study-300x200.png",300,200,true],"large":["https:\/\/www.onlinegenericmedicine.com\/news\/wp-content\/uploads\/2026\/09\/Tadalafil-Linked-to-Higher-Glaucoma-Risk-in-New-Study.png",600,400,false],"1536x1536":["https:\/\/www.onlinegenericmedicine.com\/news\/wp-content\/uploads\/2026\/09\/Tadalafil-Linked-to-Higher-Glaucoma-Risk-in-New-Study.png",600,400,false],"2048x2048":["https:\/\/www.onlinegenericmedicine.com\/news\/wp-content\/uploads\/2026\/09\/Tadalafil-Linked-to-Higher-Glaucoma-Risk-in-New-Study.png",600,400,false]},"rttpg_author":{"display_name":"medicine","author_link":"https:\/\/www.onlinegenericmedicine.com\/news\/author\/medicine\/"},"rttpg_comment":0,"rttpg_category":"<a href=\"https:\/\/www.onlinegenericmedicine.com\/news\/category\/eye-ear-care\/\" rel=\"category tag\">Eye &amp; Ear Care<\/a> <a href=\"https:\/\/www.onlinegenericmedicine.com\/news\/category\/mens-health\/\" rel=\"category tag\">Men\u2019s Health<\/a>","rttpg_excerpt":"A widely used medication for erectile dysfunction and urinary symptoms associated with an enlarged prostate has been linked to a higher risk of glaucoma in a new multinational study. The medication, tadalafil, is a phosphodiesterase type 5 (PDE5) inhibitor also known by the brand name Cialis. While tadalafil is commonly prescribed for erectile dysfunction, it&hellip;","_links":{"self":[{"href":"https:\/\/www.onlinegenericmedicine.com\/news\/wp-json\/wp\/v2\/posts\/1184","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.onlinegenericmedicine.com\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.onlinegenericmedicine.com\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.onlinegenericmedicine.com\/news\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.onlinegenericmedicine.com\/news\/wp-json\/wp\/v2\/comments?post=1184"}],"version-history":[{"count":1,"href":"https:\/\/www.onlinegenericmedicine.com\/news\/wp-json\/wp\/v2\/posts\/1184\/revisions"}],"predecessor-version":[{"id":1186,"href":"https:\/\/www.onlinegenericmedicine.com\/news\/wp-json\/wp\/v2\/posts\/1184\/revisions\/1186"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.onlinegenericmedicine.com\/news\/wp-json\/wp\/v2\/media\/1185"}],"wp:attachment":[{"href":"https:\/\/www.onlinegenericmedicine.com\/news\/wp-json\/wp\/v2\/media?parent=1184"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.onlinegenericmedicine.com\/news\/wp-json\/wp\/v2\/categories?post=1184"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.onlinegenericmedicine.com\/news\/wp-json\/wp\/v2\/tags?post=1184"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}